Results 91 to 100 of about 46,345 (342)

On the uniqueness theorem of Holmgren [PDF]

open access: yes, 2014
We rereview the classical Cauchy-Kovalevskaya theorem and the related uniqueness theorem of Holmgren, in the simple setting of powers of the Laplacian and a smooth curve segment in the plane.
Hedenmalm, Haakan
core  

Flatness-based Deformation Control of an Euler-Bernoulli Beam with In-domain Actuation

open access: yes, 2015
This paper addresses the problem of deformation control of an Euler-Bernoulli beam with in-domain actuation. The proposed control scheme consists in first relating the system model described by an inhomogeneous partial differential equation to a target ...
Badkoubeh, Amir   +2 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Robust multilevel average controller for trajectory tracking in mobile robots powered by solar panels: Integrating actuators and power electronics stage

open access: yesResults in Engineering
This paper addresses the challenge of bidirectional trajectory tracking, for the first time in the literature, in wheeled mobile robots (WMRs) powered by renewable energy by thoroughly considering all involved subsystems.
Erik Reyes-Reyes   +8 more
doaj   +1 more source

Robust Tracking Controller for a DC/DC Buck-Boost Converter–Inverter–DC Motor System

open access: yesEnergies, 2018
This paper has two aims. The first is to develop a robust hierarchical tracking controller for the DC/DC Buck-Boost–inverter–DC motor system.
Eduardo Hernández-Márquez   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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