Results 71 to 80 of about 46,345 (342)
工程科学学报, 2017 In order to reveal the mechanical essence of the detecting principle of SI-FLAT flatness measurement systems, the mathematical model of the relationship between amplitude and residual stress was established, based on the theory of fluid-structure ...
LI Nong +6 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Non-linear estimation is easy [PDF]
, 2007 Non-linear state estimation and some related topics, like parametric estimation, fault diagnosis, and perturbation attenuation, are tackled here via a new methodology in numerical differentiation.
Fliess, Michel +2 more
core +4 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Accurate Tracking of Agile Trajectories for a Tail-Sitter UAV Under Wind Disturbances Environments
DronesTo achieve more robust and accurate tracking control of high maneuvering trajectories for a tail-sitter fixed-wing unmanned aerial vehicle (UAV) operating within its full envelope in outdoor environments, a novel control approach is proposed.
Xu Zou +3 more
doaj +1 more source
Explicit Flatness-Based Guidance in Reentry Phase [PDF]
فصلنامه علوم و فناوری فضایی, 2014 An explicit guidance law is developed for a reentry vehicle. Motion is constrained to a three-dimensional Bezier curve. Acceleration commands are derived by solving an inverse problem that combined with differential flatness approach.
R. Esmaelzadeh
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Mission Planning and Control of Multi-Aircraft Systems With Signal Temporal Logic Specifications
IEEE Access, 2019 This paper focuses on optimization-based control of multi-aircraft systems that have several mission objectives. Signal Temporal Logic (STL) is used to express the mission specifications that combine temporal and logical constraints.
Baris Baspinar +2 more
doaj +1 more source
Configuration Flatness of Lagrangian Systems Underactuated by One Control [PDF]
, 1996 Lagrangian control systems that are differentially flat with flat outputs that only depend on configuration variables are said to be configuration flat.
Murray, Richard M., Rathinam, Muruhan
core +5 more sources