Results 61 to 70 of about 1,174,241 (301)

Sliding Mode Control of Quadrotor based on Differential Flatness

open access: yes, 2018
International audienceIn this work, the differential flatness property and the sliding mode controller design are proposed for a quadrotor in order to track a predefined reference trajectory despite the presence of uncertain parameters.
Hadj Brahim, Anis Ben   +4 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Weak factorization systems for S-acts

open access: yes, 2013
The concept of a weak factorization system has been studied extensively in homotopy theory and has recently found an application in one of the proofs of the celebrated flat cover conjecture, categorical versions of which have been presented by a number ...
Renshaw, James   +3 more
core   +1 more source

Accurate Tracking of Agile Trajectories for a Tail-Sitter UAV Under Wind Disturbances Environments

open access: yesDrones
To achieve more robust and accurate tracking control of high maneuvering trajectories for a tail-sitter fixed-wing unmanned aerial vehicle (UAV) operating within its full envelope in outdoor environments, a novel control approach is proposed.
Xu Zou   +3 more
doaj   +1 more source

Spherical Inverted Pendulum on a Quadrotor UAV: A Flatness and Discontinuous Extended State Observer Approach

open access: yesMachines, 2023
This article addresses the problem of balancing an inverted spherical pendulum on a quadrotor. The full dynamic model is obtained via the Euler-Lagrange formalism, where the dynamics of the pendulum is coupled to the dynamics of the quadrotor, taking as ...
Adrian H. Martinez-Vasquez   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Explicit Flatness-Based Guidance in Reentry Phase [PDF]

open access: yesفصلنامه علوم و فناوری فضایی, 2014
An explicit guidance law is developed for a reentry vehicle. Motion is constrained to a three-dimensional Bezier curve. Acceleration commands are derived by solving an inverse problem that combined with differential flatness approach.
R. Esmaelzadeh
doaj  

Analysis of fluid-structure interaction vibration based on the detection principle of SI-FLAT flatness measurement systems

open access: yes工程科学学报, 2017
In order to reveal the mechanical essence of the detecting principle of SI-FLAT flatness measurement systems, the mathematical model of the relationship between amplitude and residual stress was established, based on the theory of fluid-structure ...
LI Nong   +6 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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