FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Zero differential resistance state of two dimensional electron systems in strong magnetic fields
, 2007 Zero differential resistance state is found in response to direct current applied to 2D electron systems at strong magnetic field and low temperatures. Transition to the state is accompanied by sharp dip of negative differential resistance, which occurs ...
A. A. Bykov +5 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Differential cellular contractility as a mechanism for stiffness sensing
New Journal of Physics, 2019 The ability of cells to sense and respond to the mechanical properties of their environments is fundamental to a range of cellular behaviours, with substrate stiffness increasingly being found to be a key signalling factor.
Carina Dunlop
doaj +1 more source
Integrated Transcriptomic and Metabolomic Analyses Uncover the Differential Mechanism in Saline-Alkaline Tolerance between Indica and Japonica Rice at the Seedling Stage. [PDF]
Int J Mol Sci, 2023 Wang J +6 more
europepmc +1 more source
Dynamics of a deformable self-propelled domain
, 2010 We investigate the dynamical coupling between the motion and the deformation of a single self-propelled domain based on two different model systems in two dimensions.
Alexander G. P. +9 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Study on utility optimization for randomized response mechanism
Tongxin xuebao, 2019 For the study of privacy-utility trade-off in local differential privacy,the utility optimization models of binary generalized random response mechanism for the case of differential privacy and approximate differential privacy were established.By graphic
Yihui ZHOU, Laifeng LU, Zhenqiang WU
doaj +2 more sources
Design of Coaxial Differential Planetary Mechanism Reducer
Jixie chuandong, 2015 In order to study the gear transmission principle of differential planetary mechanism of reducer,the teeth-distributing calculating and the transmission ratio confirming of the differential mechanism are carried out.According to the analysis and ...
Song Qihui, Qi Keqiang, Kong Fankun
doaj
Integrated Metabolomic and Transcriptomic Analysis Reveals Differential Mechanism of Flavonoid Biosynthesis in Two Cultivars of Angelica sinensis. [PDF]
Molecules, 2022 Zhu T +6 more
europepmc +1 more source