Results 141 to 150 of about 2,043,354 (309)

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Non-targeted metabolomic analysis of non-volatile metabolites in a novel Chinese industrially fermented low-salt kohlrabi

Frontiers in Nutrition
Low-temperature and low-salt fermented Chinese kohlrabi (LSCK) represents a novel approach to producing low-salt kohlrabi without the need for desalination during processing, as compared to traditional techniques. However, the profile of its non-volatile
Xiaohan Jia, Xiaohan Jia, Xinyi Wang, Hongfan Chen, Hongfan Chen, Dayu Liu, Bo Deng, Ling Ao, Jianping Yang, Xin Nie, Zhiping Zhao   +10 more
doaj   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Metabolomic Characteristics of Patients With Non-Small Cell Lung Cancer in Plasma, Tissue and Exhaled Breath Condensate: A Case-Control Study

Technology in Cancer Research & Treatment
Introduction Lung cancer is a malignant tumor with high global incidence and mortality. Early screening and diagnosis can substantially extend patient survival, yet achieving this remains a challenging objective.
Dewei Li, Shuting Yang, Ling Zhang, Lingling Dong, Yueeryeti Sailai, Limin Yao, Chengyu Jin, Xuemei Wei   +7 more
doaj   +1 more source

The differential metabolites in the plasma between G6PDx-FB and G6PDx control mice.

, 2016
The differential metabolites in the plasma between G6PDx-FB and G6PDx control mice.
Guobing Zhong (3178971), Dongjing Yan (3178965), Huazong Zeng (304005), Wangwei Cai (3178968), Guankui Du (3178974), Man Xiao (556153)   +5 more
core   +1 more source

Differential antiangiogenic and anticancer activities of the active metabolites of ginsenoside Rg3

Journal of Ginseng Research
Epimers of ginsenoside Rg3 (Rg3) have a low bioavailability and are prone to deglycosylation, which produces epimers of ginsenoside Rh2 (S-Rh2 and R-Rh2) and protopanaxadiol (S-PPD and R-PPD). The aim of this study was to compare the efficacy and potency of these molecules as anti-cancer agents.Crystal violet staining was used to study the anti ...
Maryam Nakhjavani, Eric Smith, Kenny Yeo, Yoko Tomita, Timothy J. Price, Andrea Yool, Amanda R. Townsend, Jennifer E. Hardingham   +7 more
openaire   +3 more sources

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Differential Selectivity of Human and Mouse ABCC4/Abcc4 for Arsenic Metabolites

Drug Metabolism and Disposition
Millions of people globally are exposed to the proven human carcinogen arsenic at unacceptable levels in drinking water. In contrast, arsenic is a poor rodent carcinogen, requiring >100-fold higher doses for tumor induction, which may be explained by toxicokinetic differences between humans and mice.
Brayden D. Whitlock, Yingze Ma, Gwenaëlle Conseil, Alicia R. O’Brien, Mayukh Banerjee, Diane P. Swanlund, Z. Ping Lin, Yao Wang, X. Chris Le, John D. Schuetz, Susan P.C. Cole, Elaine M. Leslie   +11 more
openaire   +2 more sources

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source