Results 131 to 140 of about 3,536,382 (331)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Differential and holomorphic differential operators on noncommutative algebras [PDF]

open access: yesRussian Journal of Mathematical Physics, 2015
31 pages. Comments welcome on the contents or on references that should be added for a possible revised version.
openaire   +4 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Unified study on characteristic spectrum representation of signals and spectral decomposition for stationary random signals

open access: yesTongxin xuebao, 2018
The unified relationship between the signal characteristic spectrum representation and the spectral decomposition for the stationary random signal was deeply studied.
Hongyu WANG, Tianshuang QIU
doaj   +2 more sources

THE SOLUTION OF EULER-CAUCHY EQUATION EXPRESSED BY DIFFERENTIAL OPERATOR USING LAPLACE TRANSFORM

open access: yes, 2013
It is well known fact that the Laplace transform is useful in solving linear ordinary differential equations with constant coefficients such as free/forced oscillations, but in the case of differential equation with variable coefficients is not. In here,
H. Kim
semanticscholar   +1 more source

Limited operators and differentiability

open access: yes, 2016
We characterize the limited operators by differentiability of convex continuous functions. Given Banach spaces $Y$ and $X$ and a linear continuous operator $T: Y \longrightarrow X$, we prove that $T$ is a limited operator if and only if, for every convex continuous function $f: X \longrightarrow \R$ and every point $y\in Y$, $f\circ T$ is Fr chet ...
openaire   +3 more sources

DIFFERENTIAL EQUATIONS AND INTERTWINING OPERATORS [PDF]

open access: yesCommunications in Contemporary Mathematics, 2005
We show that if every module W for a vertex operator algebra V = ∐n∈ℤV(n) satisfies the condition dim W/C1(W)<∞, where C1(W) is the subspace of W spanned by elements of the form u-1w for u ∈ V+ = ∐n>0 V(n) and w ∈ W, then matrix elements of products and iterates of intertwining operators satisfy certain systems of differential equations ...
openaire   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Spectral Expansion for the Asymptotically Spectral Periodic Differential Operators [PDF]

open access: yesarXiv, 2016
In this paper we investigate the spectral expansion for the asymptotically spectral differential operators generated in all real line by ordinary differential expression of arbitrary order with periodic matrix-valued ...
arxiv  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

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