Results 71 to 80 of about 86,356 (264)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

On Certain Analogues of Noor Integral Operators Associated with Fractional Integrals

Journal of Function Spaces
In this paper, we employ a q-Noor integral operator to perform a q-analogue of certain fractional integral operator defined on an open unit disc. Then, we make use of the Hadamard convolution product to discuss several related results.
Mojtaba Fardi, Ebrahim Amini, Shrideh Al-Omari   +2 more
doaj   +1 more source

Unified study on characteristic spectrum representation of signals and spectral decomposition for stationary random signals

Tongxin xuebao, 2018
The unified relationship between the signal characteristic spectrum representation and the spectral decomposition for the stationary random signal was deeply studied.
Hongyu WANG, Tianshuang QIU
doaj   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The Maximal Regularity of Nonlinear Second-Order Hyperbolic Boundary Differential Equations

Axioms
In this paper, we show the maximal regularity of nonlinear second-order hyperbolic boundary differential equations. We aim to show if the given second-order partial differential operator satisfies the specific ellipticity condition; additionally, if ...
Xingyu Liu
doaj   +1 more source

Study of simply connected convex domain and its geometric properties (II)

Journal of Taibah University for Science, 2019
In this paper, making use of a new integral operator defined in the open unit disk we introduce and study a new class of simply connected convex domain of analytic and univalent functions.
M. I. Faisal
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

BRST operator for quantum Lie algebras and differential calculus on quantum groups [PDF]

, 2001
A. P. Isaev, O. Ogievetsky
openalex   +1 more source

Local solvability and stability of an inverse spectral problem for higher-order differential operators [PDF]

, 2023
Natalia P. Bondarenko
openalex   +1 more source