Results 141 to 150 of about 4,395,934 (279)

Genomic imprinting defects in the growth disorder Beckwith-Wiedemann syndrome [PDF]

, 2009
The imprinting control region (IC1) of the human IGF2 and H19 genes is represented by a chromatin insulator located between the two genes that prevents the activation of IGF2 and allows the activation of H19 on the maternal chromosome. Deletions removing
Citro, Valentina
core   +1 more source

DNA Imprinting and Differentially Expressed Genes in Longissimus thoracis Muscle of Bos indicus Submitted to Early Weaning Management

Epigenomes
Background/Objectives: Early weaning management followed by energy supplementation can lead to metabolic alterations in the calf that exert long-term effects on the animal’s health and performance.
Gustavo Tinoco, Gustavo Russo, Rogério Curi, Marcelo Vicari, Paloma Melo, Isabella Souza, Juliana Torrecilhas, Philipe Moriel, Welder Baldassini, Luis Chardulo, Otávio Neto, Guilherme Pereira   +11 more
doaj   +1 more source

Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg, Cecilia Fugmann, Juliana Imgenberg‐Kreuz   +2 more
wiley   +1 more source

Heatmap of 15 highly differentially methylated loci.

, 2019
Unsupervised hierarchical clustering of differentially methylated loci (rows) in 8 affected and 10 control samples (columns). These 15 CpG loci are at least either 2.0-fold hypomethylated or 2.0-fold hypermethylated with False Detection Rate < 0.00001 in
Sangeetha Vishweswaraiah (429990), Deepthi Mahishi (6494951), Alosh Baraa (6494948), Ray O. Bahado-Singh (804903), Rouba Ali-Fehmi (345065), Nazia Saiyed (6494954), Samet Albayrak (2734897), Chittibabu Guda (13806), Uppala Radhakrishna (804909), Nitish K. Mishra (589321), Avinash M. Veerappa (429989), Rita Zafra (5746679)   +11 more
core   +1 more source

Grandparent Prenatal Tobacco, Alcohol, Coffee, and Tea Consumption and Autism in the Third Generation

Autism Research, EarlyView.
ABSTRACT Exogenous prenatal exposures may affect neurodevelopment across multiple generations. We investigated grandmother and grandfather smoking, alcohol, coffee, and tea consumption during pregnancy in relation to their grandchildren's risk of autism spectrum disorder (ASD).
Michelle Pearl, Kimberly Berger, Piera M. Cirillo, Nickilou Y. Krigbaum, Victor Poon, Gayle C. Windham, Barbara A. Cohn   +6 more
wiley   +1 more source

Differentially methylated CpGs.

CpG sites significantly differentially methylated between time points of the experiment (FDR week_1_score to week_25_score), unique position of site in Atlantic salmon genome (uniq_pos), chromosome of site (chr), base position on chromosome (locus), log2
Thomas N. Harvey (5015138), Fabian Grammes (502784), Line L. Røsæg (10642951), Jon Olav Vik (9666588), Gareth B. Gillard (10642948), Torgeir R. Hvidsten (262006), Øystein Monsen (10642954), Simen R. Sandve (3265908)   +7 more
core   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Mechanistic Insights Into Sustainable Catalytic Pyrolysis of Biomass‐Derived Ferulic Acid: The Role of Alumina Regeneration

Chemistry – A European Journal, EarlyView.
Surface‐bound ferulate phenolate complexes undergo styrene‐like polymerization on alumina, yielding a polymeric carbonaceous layer that progressively transforms into polyaromatic carbon domains with concomitant release of aromatic products, while parallel surface‐assisted decarboxylation produces 4‐vinylguaiacol. ABSTRACT A fundamental understanding of
Tetiana V. Kulik, Borys B. Palianytsia, Mykola M. Ilchenko, Nataliia S. Nastasiienko, David J. Morgan, Liudmila P. Storozhuk, David J. Willock, Greg Shaw, Duncan F. Wass, Rafael Luque, Philip R. Davies, Mykola T. Kartel   +11 more
wiley   +1 more source

Heatmap of 26 highly differentially methylated loci.

, 2018
DNA methylation profiling based on unsupervised hierarchical clustering identified four unique clusters that have distinct methylation signatures. These 26 targets represent the most highly differentially methylated loci (False Detection Rate < 0.000001).
Sangeetha Vishweswaraiah (429990), Nazia M. Saiyed (5746685), Prajna H. Sitharam (5746682), Samet Albayrak (2734897), Chittibabu Guda (13806), Uppala Radhakrishna (804909), Nitish K. Mishra (589321), Avinash M. Veerappa (429989), Rita Zafra (5746679), Ray Bahado-Singh (5746688)   +9 more
core   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source