Results 1 to 10 of about 6,101,774 (389)

Inhibition of MAD2L1 Mediates Pulmonary Fibrosis through Impairment of Mitochondrial Function and Induction of Cell Senescence

open access: yesCanadian Respiratory Journal, 2022
Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading
Lan Wang   +7 more
doaj   +1 more source

Overview of CircRNAs Roles and Mechanisms in Liver Fibrosis

open access: yesBiomolecules, 2023
Liver fibrosis represents the reversible pathological process with the feature of the over-accumulation of extracellular matrix (ECM) proteins within the liver, which results in the deposition of fibrotic tissues and liver dysfunction. Circular noncoding
Gaiping Wang   +6 more
doaj   +1 more source

Point-Substitution of Phenylalanine Residues of 26RFa Neuropeptide: A Structure-Activity Relationship Study

open access: yesMolecules, 2021
26RFa is a neuropeptide that activates the rhodopsin-like G protein-coupled receptor QRFPR/GPR103. This peptidergic system is involved in the regulation of a wide array of physiological processes including feeding behavior and glucose homeostasis. Herein,
Benjamin Lefranc   +12 more
doaj   +1 more source

Mitochondrial Dysfunction and Chronic Liver Disease

open access: yesCurrent Issues in Molecular Biology, 2022
Mitochondria are generally considered the powerhouse of the cell, a small subcellular organelle that produces most of the cellular energy in the form of adenosine triphosphate (ATP). In addition, mitochondria are involved in various biological functions,
Chunyan Zhang   +5 more
doaj   +1 more source

Cryo-derived plants through embryogenesis showed same levels of vinblastine and vincristine (anticancer) in Catharanthus roseus and had normal genome size

open access: yesScientific Reports, 2022
Cryopreservation of rare plant materials is an important approach for preserving germplasms and is a good added concept to tissue banking. The preservation of embryogenic cell suspensions is even more valuable as the tissues facilitate in producing ...
A. Mujib   +2 more
doaj   +1 more source

Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos

open access: yesAnimal Cells and Systems, 2020
Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicated gene regulatory network and genes involved in this ...
Zobia Umair   +9 more
doaj   +1 more source

Generation of High Quality Memory B Cells

open access: yesFrontiers in Immunology, 2022
Protection against pathogen re-infection is mediated, in large part, by two humoral cellular compartments, namely, long-lived plasma cells and memory B cells.
Takeshi Inoue   +4 more
doaj   +1 more source

Differentiation of Schistosoma haematobium from related schistosomes by PCR amplifying an inter-repeat sequence. [PDF]

open access: yes, 2007
Schistosoma haematobium infects nearly 150 million people, primarily in Africa, and is transmitted by select species of local bulinid snails. These snails can host other related trematode species as well, so that effective detection and monitoring of ...
Abbasi, Ibrahim   +5 more
core   +1 more source

DNA methylation dynamics in the rat EGF gene promoter after partial hepatectomy

open access: yesGenetics and Molecular Biology, 2014
Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration.
Deming Li   +3 more
doaj   +1 more source

Delayed Liver Regeneration after Partial Hepatectomy in Aged Nos2 Knockout Mice

open access: yesCell Journal, 2017
Objective Patients over 60 years of age have higher mortality and morbidity after major liver resections. Nitric oxide (NO) derived from the catalytic activity of Nos2 plays a beneficial role in liver regeneration (LR) after partial hepatectomy (PH). In
Deming Li   +6 more
doaj   +1 more source

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