Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. [PDF]
, 2017 The vascular endothelium is critical for induction of appropriate lineage differentiation in organogenesis. In this study, we report that dysfunctional pulmonary endothelium, resulting from the loss of matrix Gla protein (MGP), causes ectopic hepatic ...
Blazquez-Medela, Ana M +9 more
core +2 more sources
Differentiation Requires Continuous Regulation [PDF]
, 1991 An abstract for this item is not ...
Baltimore, David, Blau, Helen M.
core +1 more source
Differential inclusions for differential forms [PDF]
Calculus of Variations and Partial Differential Equations, 2006 We study necessary and sufficient conditions for the existence of solutions in \(W^{1,\infty}_0 (\Omega; \Lambda^{k}(\mathbb{R}^n))\) of the problem \({\rm d}\omega (x)\in E,\quad \text{a.e. in }\Omega\) where \(E\subseteq\Lambda^{k+1}(\mathbb{R}^{n})\) is a given set. Special attention is given to the case of the curl (i.e.
Bandyopadhyay, Saugata +3 more
openaire +4 more sources
Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]
, 2015 We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana +2 more
core +4 more sources
A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells. [PDF]
, 2019 Pancreatic endocrine cell differentiation is orchestrated by the action of transcription factors that operate in a gene regulatory network to activate endocrine lineage genes and repress lineage-inappropriate genes.
Carrano, Andrea C +15 more
core +2 more sources
Palmitate differentially regulates the polarization of differentiating and differentiated macrophages [PDF]
Immunology, 2015 SummaryThe tissue accumulation of M1 macrophages in patients with metabolic diseases such as obesity and type 2 diabetes mellitus has been well‐documented. Interestingly, it is an accumulation of M2 macrophages that is observed in the adipose, liver and lung tissues, as well as in the circulation, of patients who have had major traumas such as a burn ...
Peter Qi +6 more
openaire +3 more sources
MicroRNA-222 regulates muscle alternative splicing through Rbm24 during differentiation of skeletal muscle cells [PDF]
, 2016 A number of microRNAs have been shown to regulate skeletal muscle development and differentiation. MicroRNA-222 is downregulated during myogenic differentiation and its overexpression leads to alteration of muscle differentiation process and specialized ...
Cappella, Marisa +7 more
core +2 more sources
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
FEBS Letters, EarlyView.Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta +3 more
wiley +1 more source
Role of Prion protein-EGFR multimolecular complex during neuronal differentiation of human dental pulp-derived stem cells [PDF]
, 2018 Cellular prion protein (PrPC) is expressed in a wide variety of stem cells in which regulates their self-renewal as well as differentiation potential. In this study we investigated the presence of PrPCin human dental pulp-derived stem cells (hDPSCs) and ...
Manganelli, Valeria +6 more
core +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source