Results 11 to 20 of about 6,101,774 (389)

Differentiation of Differentiation [PDF]

open access: yesSSRN Electronic Journal, 2012
Increased global competitiveness, reduced product life cycles, rapid technological advancements, and dynamic customer requirements have drastically altered the nature of competition. Henderson (1989) argues that two firms cannot coexist if they make their livings in identical ways and that’s the reason why firm distinguish from its rivals.
Valentina Ivančić, Lara Jelenc
openaire   +2 more sources

Cell cycle: To differentiate or not to differentiate? [PDF]

open access: yesCurrent Biology, 2000
Developmental regulation of the cell cycle is an important determinant of tissue size and shape. Equally important is regulated withdrawal from the cell cycle to allow cells to differentiate. Recent evidence supports a direct link between transcriptional regulation of the cell cycle machinery and cell differentiation.
Robert J. Duronio, Denise L. Myster
openaire   +2 more sources

Machine learning identifies phenotypic profile alterations of human dopaminergic neurons exposed to bisphenols and perfluoroalkyls

open access: yesScientific Reports, 2023
Parkinson’s disease (PD) is the second most common neurodegenerative disease and is characterized by the loss of midbrain dopaminergic neurons. Endocrine disrupting chemicals (EDCs) are active substances that interfere with hormonal signaling. Among EDCs,
Andrea Di Credico   +6 more
doaj   +1 more source

Rapid generation of secondary fibroblasts through teratoma formation

open access: yesBioTechniques, 2015
The use of secondary or reprogrammable cells in the production of induced pluripotent stem cells (iPSCs) circumvents random infection by various viral particles and random, uncontrollable integrations of the viral genomes into different genomic loci.
Sang Mi Cho   +4 more
doaj   +1 more source

Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification

open access: yesCancer Biology & Therapy, 2023
The possible anticancer activity of combination (M + E + F) of metformin (M), efavirenz (E), and fluoxetine (F) was investigated in normal HDF cells and HCT116 human colon cancer cells.
Beom-Goo Kang   +13 more
doaj   +1 more source

The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis. [PDF]

open access: yes, 2018
Bone marrow mesenchymal stem cells (BMSCs), the important component and regulator of bone marrow microenvironment, give rise to hematopoietic-supporting stromal cells and form hematopoietic niches for hematopoietic stem cells (HSCs).
Li, Shengwen Calvin   +6 more
core   +2 more sources

N-Acetylcysteine Reduces the Pro-Oxidant and Inflammatory Responses during Pancreatitis and Pancreas Tumorigenesis

open access: yesAntioxidants, 2021
Pancreatitis, an inflammation of the pancreas, appears to be a main driver of pancreatic cancer when combined with Kras mutations. In this context, the exact redox mechanisms are not clearly elucidated.
Marie-Albane Minati   +4 more
doaj   +1 more source

Terminal differentiation of adult hippocampal progenitor cells is a step functionally dissociable from proliferation and is controlled by Tis21, Id3 and NeuroD2 [PDF]

open access: yes, 2017
Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Daniele Saraulli   +9 more
core   +2 more sources

Efficient definitive endoderm induction from mouse embryonic stem cell adherent cultures: A rapid screening model for differentiation studies

open access: yesStem Cell Research, 2014
Definitive endoderm (DE) differentiation from mouse embryonic stem cell (mESC) monolayer cultures has been limited by poor cell survival or low efficiency.
Josué Kunjom Mfopou   +6 more
doaj   +1 more source

Evidence for an interplay between cell cycle progression and the initiation of differentiation between life cycle forms of African trypanosomes [PDF]

open access: yes, 1994
Successful transmission of the African trypanosome between the mammalian host blood-stream and the tsetse fly vector involves dramatic alterations in the parasite's morphology and biochemistry.
Gull, K, Matthews, K R
core   +1 more source

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