Results 21 to 30 of about 4,224,202 (187)
Journal of Translational Medicine, 2016 Background In recent years, immunomodulatory mechanisms of mesenchymal stem/stromal cells (MSCs) from bone marrow and other “classic” sources have been described. However, the phenotypic and functional properties of tumor MSCs are poorly understood.
María de Lourdes Mora-García +10 more
doaj +1 more source
Nature Communications, 2022 Limited response to immune checkpoint inhibitors has been reported in patients with castration-resistant prostate cancer. Here the authors show that intermittent, but not continuous, treatment with an anti-PI3Kα/β/δ-inhibitor promotes anti-tumor immunity
Zhi Qi +8 more
doaj +1 more source
Cannabidiol stimulates AML-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner [PDF]
, 2015 Glioma stem-like cells (GSCs) correspond to a tumor cell subpopulation, involved in glioblastoma multiforme (GBM) tumor ini- tiation and acquired chemoresistance.
Amantini, Consuelo +7 more
core +2 more sources
Generation of High Quality Memory B Cells
Frontiers in Immunology, 2022 Protection against pathogen re-infection is mediated, in large part, by two humoral cellular compartments, namely, long-lived plasma cells and memory B cells.
Takeshi Inoue +4 more
doaj +1 more source
Role of Prion protein-EGFR multimolecular complex during neuronal differentiation of human dental pulp-derived stem cells [PDF]
, 2018 Cellular prion protein (PrPC) is expressed in a wide variety of stem cells in which regulates their self-renewal as well as differentiation potential. In this study we investigated the presence of PrPCin human dental pulp-derived stem cells (hDPSCs) and ...
Manganelli, Valeria +6 more
core +1 more source
Analyze p53 degradation by 35S p53 Pulse Chase Analysis
Bio-Protocol, 2012 p53, is known as the guardian of the genome and as such requires exquisite regulation not only of its abundance but also its activity. The abundance of p53 can be modulated at the level of transcription, translation, and also via its degradation.This ...
Megan Astle +2 more
doaj +1 more source
Population Differentiation In Daphnia Alters Community Assembly In Experimental Ponds [PDF]
, 2011 Most studies of community assembly ignore how genetic differentiation within species affects their colonization and extinction. However, genetic differentiation in ecologically relevant traits may be substantial enough to alter the colonization and ...
Juenger, Thomas E. +2 more
core +1 more source
Differentiating the differential rotation effect
Acta Psychologica, 2012 As an observer views a picture from different viewing angles, objects in the picture appear to maintain their orientation relative to the observer. For instance, the eyes of a portrait appear to follow the observer as he or she views the image from different angles. We have explored this rotation effect, often called the Mona Lisa effect.
Evgenia, Boyarskaya, Heiko, Hecht
openaire +2 more sources
Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease
BMC Genomics, 2018 Background Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants before and after birth.
Guoliang Lyu +11 more
doaj +1 more source
Female Farm Workers in Morocco: Between Laborious Working Conditions and Environmental Challenges [PDF]
E3S Web of Conferences, 2023 The present paper posits that female labor force in the Moroccan agricultural sector plays a crucial role in production and provides specific expertise, leading to an increasingly visible feminization of the sector.
Jehouani Rachida, Meryem Naji
doaj +1 more source