Results 21 to 30 of about 4,638,915 (335)

Efficient definitive endoderm induction from mouse embryonic stem cell adherent cultures: A rapid screening model for differentiation studies

open access: yesStem Cell Research, 2014
Definitive endoderm (DE) differentiation from mouse embryonic stem cell (mESC) monolayer cultures has been limited by poor cell survival or low efficiency.
Josué Kunjom Mfopou   +6 more
doaj   +1 more source

Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions

open access: yesJournal of Translational Medicine, 2016
Background In recent years, immunomodulatory mechanisms of mesenchymal stem/stromal cells (MSCs) from bone marrow and other “classic” sources have been described. However, the phenotypic and functional properties of tumor MSCs are poorly understood.
María de Lourdes Mora-García   +10 more
doaj   +1 more source

Overcoming resistance to immune checkpoint therapy in PTEN-null prostate cancer by intermittent anti-PI3Kα/β/δ treatment

open access: yesNature Communications, 2022
Limited response to immune checkpoint inhibitors has been reported in patients with castration-resistant prostate cancer. Here the authors show that intermittent, but not continuous, treatment with an anti-PI3Kα/β/δ-inhibitor promotes anti-tumor immunity
Zhi Qi   +8 more
doaj   +1 more source

Generation of High Quality Memory B Cells

open access: yesFrontiers in Immunology, 2022
Protection against pathogen re-infection is mediated, in large part, by two humoral cellular compartments, namely, long-lived plasma cells and memory B cells.
Takeshi Inoue   +4 more
doaj   +1 more source

Differentiation of Schistosoma haematobium from related schistosomes by PCR amplifying an inter-repeat sequence. [PDF]

open access: yes, 2007
Schistosoma haematobium infects nearly 150 million people, primarily in Africa, and is transmitted by select species of local bulinid snails. These snails can host other related trematode species as well, so that effective detection and monitoring of ...
Abbasi, Ibrahim   +5 more
core   +1 more source

Analyze p53 degradation by 35S p53 Pulse Chase Analysis

open access: yesBio-Protocol, 2012
p53, is known as the guardian of the genome and as such requires exquisite regulation not only of its abundance but also its activity. The abundance of p53 can be modulated at the level of transcription, translation, and also via its degradation.This ...
Megan Astle   +2 more
doaj   +1 more source

Differentiating the differential rotation effect

open access: yesActa Psychologica, 2012
As an observer views a picture from different viewing angles, objects in the picture appear to maintain their orientation relative to the observer. For instance, the eyes of a portrait appear to follow the observer as he or she views the image from different angles. We have explored this rotation effect, often called the Mona Lisa effect.
Evgenia, Boyarskaya, Heiko, Hecht
openaire   +2 more sources

Optimisation of growth conditions for ovine airway epithelial cell differentiation at an air-liquid interface [PDF]

open access: yes, 2018
Respiratory tract infections are of significant concern in the agriculture industry. There is a requirement for the development of well-characterised in vitro epithelial cell culture models in order to dissect the diverse molecular interactions occurring
Berry, Catherine C.   +3 more
core   +2 more sources

Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

open access: yesBMC Genomics, 2018
Background Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants before and after birth.
Guoliang Lyu   +11 more
doaj   +1 more source

Female Farm Workers in Morocco: Between Laborious Working Conditions and Environmental Challenges [PDF]

open access: yesE3S Web of Conferences, 2023
The present paper posits that female labor force in the Moroccan agricultural sector plays a crucial role in production and provides specific expertise, leading to an increasingly visible feminization of the sector.
Jehouani Rachida, Meryem Naji
doaj   +1 more source

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