Results 11 to 20 of about 3,238 (172)

Diffuse Cutaneous Mastocytosis: A Current Understanding of a Rare Disease [PDF]

International Journal of Molecular Sciences
Mastocytosis is a heterogeneous disease characterized by the expansion and accumulation of neoplastic mast cells in various tissues. Diffuse cutaneous mastocytosis (DCM) is a rare and most severe form of cutaneous mastocytosis, which typically occurs in ...
Agnieszka Rydz, Magdalena Lange, Hanna Ługowska-Umer   +2 more
exaly   +3 more sources

When Mast Cells Run Amok: A Comprehensive Review and Case Study on Severe Neonatal Diffuse Cutaneous Mastocytosis [PDF]

Genes, 2023
Neonatal diffuse cutaneous mastocytosis (NDCM) is defined as the infiltration of the epidermis by a clonal proliferation of mast cells, observed at birth, without initial signs of systemic involvement. The typical driver mutation is in the KIT gene.
Gheorghe-Emilian Olteanu, Mihaela Bataneant, Maria Puiu   +2 more
exaly   +3 more sources

Pseudoxanthomatous diffuse cutaneous mastocytosis in a child [PDF]

Journal of Krishna Institute of Medical Sciences University, 2023
Abnormal accumulation of mast cells in the skin is called cutaneous mastocytosis. Diffuse cutaneous mastocytosishas two clinical variants, pseudoxanthomatous/xanthelasmoid and bullous type. Childhood disease is mostly self limiting. This may sometimes be
Ritu Gujarati Vishwanath, Ramesh Vishwanath, Varun Vishwanath   +2 more
doaj   +2 more sources

Childhood cutaneous mastocytosis: Revisited

Indian Journal of Dermatology, 2023
Cutaneous mastocytosis is a neoplasm characterized by the proliferation and accumulation of mast cells in the skin. There can be involvement of other organ systems as well.
Bhavya Swarnkar, Rashmi Sarkar
doaj   +2 more sources

PEDIATRIC MASTOCYTOSIS: AN UPDATE

Mediterranean Journal of Hematology and Infectious Diseases, 2021
Mastocytosis is a rare clonal disorder, characterized by excessive proliferation and accumulation of mast cells (MC) in various organs and tissues. Cutaneous mastocytosis (CM), the most common form in children, is defined when MC infiltration is limited ...
Fiorina Giona
doaj   +3 more sources

Current Challenges in the Diagnosis of Pediatric Cutaneous Mastocytosis

Diagnostics, 2023
Pediatric mastocytosis is mostly a cutaneous disease classified as cutaneous mastocytosis (CM), which is characterized by mast cell (MCs) accumulation in the skin and the absence of extracutaneous involvement.
Hanna Ługowska-Umer, Justyna Czarny, Agnieszka Rydz, Roman J. Nowicki, Magdalena Lange   +4 more
doaj   +2 more sources

Challenges in the Diagnosis of Cutaneous Mastocytosis [PDF]

Diagnostics
Background: Mastocytosis is characterized by an accumulation of clonal mast cells (MCs) in tissues such as the skin. Skin lesions in mastocytosis may be clinically subtle or heterogeneous, and giving the correct diagnosis can be difficult.
Knut Brockow, Rebekka Karolin Bent, Simon Schneider, Sophie Spies, Katja Kranen, Benedikt Hindelang, Zsuzsanna Kurgyis, Sigurd Broesby-Olsen, Tilo Biedermann, Clive E. Grattan   +9 more
doaj   +2 more sources

A widespread blistering eruption: diffuse cutaneous mastocytosis [PDF]

Dermatology Online Journal, 2023
Diffuse cutaneous mastocytosis with bullous formation is a rare childhood disease. We report a 5-month-old male who presented with a 3-week history of cutaneous bullae and pruritus. On examination, he had erythema of the cheeks bilaterally and diffuse slightly hyperpigmented, indurated skin on his trunk and abdomen.
Ewulu, Adaora, Cardis, Michael A, Carter, Melody C, Habeshian, Kaiane A   +3 more
openaire   +5 more sources

Characteristics and Therapeutic Strategies for Diffuse Cutaneous Mastocytosis.

JAMA Dermatol
ImportanceDiffuse cutaneous mastocytosis (DCM) is a rare and severe subtype of pediatric mastocytosis, characterized by extensive skin involvement. Comprehensive studies on the clinical and molecular features of DCM remain limited.ObjectiveTo describe the clinical, molecular, and treatment-related characteristics and outcomes of a cohort of pediatric ...
Pernea P, Méni C, Rossignol J, Aubert H, Barbarot S, Bellon N, Bing-Lecointe AC, Bonigen J, Bursztejn AC, Carré D, Phan A, Puzenat E, Skowron F, Vabres P, Welfringer-Morin A, Drabent P, Fraitag S, Garcelon N, Agopian J, Dubreuil P, Mallet S, Barete S, Arock M, Hermine O, Bodemer C, Polivka L, CEREMAST network, and the.   +27 more
europepmc   +3 more sources

Bullous mastocytosis

Indian Journal of Dermatology, 2007
Mastocytosis is a condition characterized by the disorderly infiltration of mast cells in several tissues and comprises many different clinical situations varying from indolent cutaneous forms to malignant and systemic conditions. Bullous mastocytosis is
Nayak Surajit, Acharjya Basanti, Devi Basanti, Behera Samira   +3 more
doaj   +1 more source