Localized grain-leather plaque in urticaria pigmentosa – An unusual coexistence of dual morphology
Indian Dermatology Online Journal, 2020 Urticaria pigmentosa (UP), the most common variant of cutaneous mastocytosis (CM), is characterized by hyperpigmented, brownish macules and patches, with positive Darier's sign. Diffuse cutaneous mastocytosis (DCM), is a rare variant of CM, characterized
Sanjiv Choudhary +3 more
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Omalizumab for Pediatric Cutaneous Mastocytosis: Case Report and Review. [PDF]
Pediatr DermatolABSTRACT We report an 11‐month‐old boy with diffuse cutaneous mastocytosis whose severe pruritus and steroid dependence resolved following off‐label treatment with omalizumab. A literature review identified five additional pediatric cases in which omalizumab led to complete symptom resolution in an average of 2 months and permitted discontinuation of ...
Chang J, King A, Byrne A, Liy-Wong C.
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CD30 Expression in Neoplastic Mast Cells and the Presence of CD30+, CD3+, and PAX-5+ Tumour-Infiltrating Lymphocytes as Prognostic Markers in Canine Cutaneous Mast Cell Tumours. [PDF]
Vet Comp OncolABSTRACT Canine cutaneous mast cell tumour (MCT) is the most common skin neoplasm in dogs, with histopathology serving as both the diagnostic and primary prognostic tool. However, identifying reliable biomarkers is essential for improving clinical decision‐making.
Ramos FR +6 more
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Childhood Pseudoxanthomatousmastocytosis; Report of two cases
Indian Journal of Dermatopathology and Diagnostic Dermatology, 2018 Cutaneous mastocytosis (CM) is a mast cell proliferative disorder that commonly affects pediatric population. It has various clinical forms such as urticaria pigmentosa, solitary mastocytoma, telangiectasia macularis eruptiva perstans, diffuse CM, and ...
Bhabani S. T. P. Singh +3 more
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Journal of International Medical Research, 2020 Mastocytosis is an accumulation of clonal mast cells within tissues and it is most commonly caused by an activating mutation in the KIT gene. In this study, we report a neonatal case who presented with diffuse cutaneous mastocytosis (CM) at birth.
Yanfang Li +4 more
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Childhood cutaneous mastocytosis: Revisited
Indian Journal of Dermatology, 2023 Cutaneous mastocytosis is a neoplasm characterized by the proliferation and accumulation of mast cells in the skin. There can be involvement of other organ systems as well.
Bhavya Swarnkar, Rashmi Sarkar
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A case report of primary cutaneous marginal zone B-cell lymphoma with mastocytosis
SAGE Open Medical Case Reports, 2021 A 53-year-old man presented with asymptomatic, dusky reddish nodules on his trunk, which had persisted for 7 years. Histological findings showed nodular to diffuse dermal infiltration of lymphocytes with irregular nuclei, eosinophils, plasma cells, and ...
Hyun Yi Lee, Joong Sun Lee, Dae Won Koo
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Characteristics and outcomes of patients with pediatric-onset non-mastocytosis mast cell activation disorders: A CEREMAST study. [PDF]
Pediatr Allergy ImmunolAbstract Background Mast cell (MC) activation (MCA) disorders (MCAD) include diseases in which MCs excessively release mediators leading to recurrent manifestations of MCA. MCAD encompasses MCA syndrome (MCAS) which is defined by (i) documented systemic symptoms of MCA, (ii) a 20% increase in serum tryptase level from the individual's baseline plus 2 ...
Weiss M +25 more
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A 9-month-old Child with Diffuse Cutaneous Bullous Erythema: A Quiz [PDF]
Acta Dermato-VenereologicaShengyuan Hua +3 more
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Current Challenges in the Diagnosis of Pediatric Cutaneous Mastocytosis
Diagnostics, 2023 Pediatric mastocytosis is mostly a cutaneous disease classified as cutaneous mastocytosis (CM), which is characterized by mast cell (MCs) accumulation in the skin and the absence of extracutaneous involvement.
Hanna Ługowska-Umer +4 more
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