Results 21 to 30 of about 375 (147)
Nucleophilic Difluoromethylation of Primary Alkyl Halides Using Difluoromethyl Phenyl Sulfone as a Difluoromethyl Anion Equivalent. [PDF]
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
G K Surya, Prakash +3 more
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Beilstein Journal of Organic Chemistry, 2023 Nitrogen-containing organofluorine derivatives, which are prepared using fluorinated building blocks, are among the most important active fragments in various pharmaceutical and agrochemical products. This review focuses on the reactivity, synthesis, and
Zhang Dongxu
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Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis
Nature Communications, 2020 Heterocycles containing difluoromethyl groups are molecules with potential application in pharmaceutical, agricultural and materials science. Here, the authors show an organophotocatalytic difluoromethylation of heterocycles using O2 as green oxidant and
Wei Zhang +7 more
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New Electrophilic Difluoromethylating Reagent [PDF]
Organic Letters, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
G K Surya, Prakash +3 more
openaire +2 more sources
Visible Light-Induced Radical Cascade Difluoromethylation/Cyclization of Unactivated Alkenes: Access to CF2H‑Substituted Polycyclic Imidazoles [PDF]
ACS OmegaSheng-Nan Lin +7 more
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Nature Communications, 2021 Synthesis of fluorinated organic molecules is of high interest for agrochemistry and pharmaceutics, but efficient and general reagents for introducing -CF2- groups are lacking.
Fei Ye +5 more
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(Sila)Difluoromethylation of Fluorenyllithium with CF3H and CF3TMS
SynOpen, 2018 Difluoromethylation of the C9-H site of the fluorene ring using lithium base and fluoroform (CF3H), which is one of the most cost-effective difluoromethylating reagents, is attained to give difluoromethylated fluorenes with an all-carbon quaternary ...
Kenichi Maruyama +2 more
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Copper-based fluorinated reagents for the synthesis of CF2R-containing molecules (R ≠ F)
Beilstein Journal of Organic Chemistry, 2020 Over the years, the development of new methodologies for the introduction of various fluorinated motifs has gained a significant interest due to the importance of fluorine-containing molecules in the pharmaceutical and agrochemical industries. In a world
Louise Ruyet, Tatiana Besset
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Beilstein Journal of Organic Chemistry, 2008 BackgroundAlthough the nucleophilic difluoromethylation of aldehydes, ketones, and imines has been realized with PhSO2CF2H and related reagents, there are still no reports on the enantioselective nucleophilic reactions.ResultsWith a chiral quaternary ...
Chuanfa Ni, Fang Wang, Jinbo Hu
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Copper-catalyzed carbo-difluoromethylation of alkenes via radical relay
Nature Communications, 2021 Compounds that contain alkyl-difluoromethyl moieties are of interest for medicinal chemistry, but their synthesis is challenging. Here, the authors report a copper-catalyzed radical relay approach for the carbodifluoromethylation of alkenes that ...
Aijie Cai +7 more
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