Results 81 to 90 of about 23,235 (228)
New Paths to Spatial Expression from a Digital Humanities Perspective
Redai diliIn the context of the digital age, digital humanities has evolved into a cutting-edge interdisciplinary field that deeply integrates computational and humanistic thinking, representing a fundamental shift in research paradigms driven by data, employing ...
Zhuang Liang, Ye Chao
doaj +1 more source
Interpreters as Vital (Re)Tellers of China's Reform and Opening-Up Meta-Narrative: A Digital Humanities (DH) Approach to Institutional Interpreters' Mediation. [PDF]
Front Psychol, 2022 Gu C.
europepmc +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
A fragment-based approach for computing the long-term visual evolution of historical maps
Humanities & Social Sciences CommunicationsCartography, as a strategic technology, is a historical marker. Maps are tightly connected to the cultural construction of the environment. The increasing availability of digital collections of historical map images provides an unprecedented opportunity ...
Remi Petitpierre +3 more
doaj +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel +5 more
wiley +1 more source
Digital Studies of Culture in Central Europe: Introduction to the Thematic Section
Colloquia HumanisticaThe idea for this issue of the journal, as well as the earlier project Mapping and Boosting Digital Humanities in the Visegrad Region (led by the NGO Centre of the Study of Popular Culture), stemmed from reflections on the growing dependence of the ...
Robert Kulmiński, Ondřej Daniel
doaj +1 more source
Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source