Results 61 to 70 of about 212,627 (263)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Revisiting the Home Literacy Environment in the Digital Age: Insights from a High-SES Context

open access: yesEducation Sciences
Decades of research have documented the critical role of parental practices, beliefs, and resources in shaping children’s literacy development.
Besjanë Krasniqi   +3 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Dampak strategi membaca digital, dialogis, dan tradisional terhadap keterampilan bahasa, pemahaman cerita, dan penalaran kausal: Studi komparatif

open access: yesDiglosia
The purpose of this study was to investigate the comparative impact of three strategies, namely digital reading, dialogic reading, and traditional reading, on students' receptive and expressive language skills, story comprehension, and causal reasoning ...
Ria Candra Dewi
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Digital reading: genealogy of formation and prospects for its development in a digitalized society

open access: yesБиблиосфера, 2019
The theme of digital reading is becoming ever more relevant with a growing understanding of the importance of reading for developing both an individual and society as a whole.
Yu. P. Melentieva
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Digital Reading in the Context of Media-Critical Discourses

open access: yesOn_Culture
With the transformation of media in the context of digitization, reading is once again becoming a highly debated topic. Not only are fears being expressed that the end of the ‘Gutenberg Galaxy’ will set back the spread of reading as a cultural technique,
Susanne Düwell
doaj   +1 more source

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