Results 71 to 80 of about 41,969,480 (328)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
DIGITAL READING DURING THE PANDEMIC: EXPLORING VOCATIONAL STUDENTS’ PERCEPTIONS
This study was aimed at exploring vocational school students’ perceptions of their digital reading during the pandemic and their utilization of various digital media.
Diana Purwaningrum +11 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
On Reading Reading: Fundamental Problems of “Méta-lecture”
In his essay “Sur la Lecture,” Roland Barthes (1984) expresses his doubts regarding what he calls “Méta-lecture,” or the reading of reading. It is nothing but “un éclat d’idées, de craintes, de désirs, de jouissances, d’oppressions.” My essay ...
Elias Kreuzmair
doaj +1 more source
Younger generations are receiving their first regular digital device access at progressively earlier ages than previous generations on average, whereas disparities in their early digital device access are still being observed globally.
Jie Hu, Jing-Dan Hu
semanticscholar +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Through the analysis of the strategies of Webtoon, a Korean reading platform aimed at capturing the teenage audience as a priority and defined here as a medium, at the crossroads of production and appropriation practices, this article aims to question ...
Florence Rio, Elsa Tadier
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
BACKGROUND Text comprehension is a major obstacle for many Primary school students with special education needs (SEN). Reading episodes bring students opportunities to be exposed to new vocabulary and knowledge, potentially boosting their development of ...
C. Vargas +6 more
semanticscholar +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source

