Results 61 to 70 of about 205,289 (220)

Security of the digital transformation

Computers & Security, 2021
© 2021 The Author(s)In the early days of computation the focus was mainly on designing, developing, maintaining, and administering infrastructures and information systems housed in data centers. To this extend, security was traditionally organized around the basic technical components (e.g. data center facilities).
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Vox Populi, Vox ChatGPT: Large Language Models, Education and Democracy

Philosophies
In the era of generative AI and specifically large language models (LLMs), exemplified by ChatGPT, the intersection of artificial intelligence and human reasoning has become a focal point of global attention.
Niina Zuber, Jan Gogoll
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Digital transformation during a lockdown

International Journal of Information Management, 2020
These are indeed exceptional and historic times, a global pandemic and public health emergency sitting side by side with heightened public awareness of the injustices of decades of institutional racism. This article considers the current pandemic and lockdown period through a VUCA lens and offers reflection on how the pandemic revealed the fragility of
Fletcher, G, Griffiths, M
openaire   +3 more sources

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Optimizing Virtual Power Plants with Parallel Simulated Annealing on High-Performance Computing

Smart Cities
This work focuses on optimizing the scheduling of virtual power plants (VPPs)—as implemented in the Portuguese national project New Generation Storage (NGS)—to maximize social welfare and enhance energy trading efficiency within modern energy grids.
Ali Abbasi, Filipe Alves, Rui A. Ribeiro, João L. Sobral, Ricardo Rodrigues   +4 more
doaj   +1 more source

Digital transformation and financial inclusion

SSRN Electronic Journal, 2020
The paper explores some of the main regulatory concerns and market barriers created by the digital transformation of the financial services industry and the implications for a more socially-inclusive financial system, particularly in developing and emerging market countries.
Kern Alexander, Kern Alexander, Xenia Elisa Karametaxas, Xenia Elisa Karametaxas   +3 more
openaire   +4 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

UI/UX design requirements for young stroke survivors: recommendations from the literature

npj Digital Medicine
There is currently no single resource for UI/UX guidelines and design standards that encapsulates all the requirements for young stroke survivors (
Deborah Passey, Hasan Ferdous, Kara Burns, Cecily Gilbert, Emma Power, Tanya Rose, Julie Bernhardt, Vincent Thijs, Daniel Capurro   +8 more
doaj   +1 more source