Results 1 to 10 of about 6,589 (233)

Digitalis Therapy Is Associated With an Increased Risk of ICD Shock Delivery and Device Revision [PDF]

Annals of Noninvasive Electrocardiology
Background Digitalis glycosides are employed for rate control of atrial fibrillation and treatment of heart failure. Previous studies suggested potential harmful effects of digitalis therapy.
Gerrit Frommeyer, Philipp S. Lange, Thomas Kleemann, Christoph Stellbrink, Hüseyin Ince, Johannes Brachmann, Thorsten Lewalter, Matthias Hochadel, Jochen Senges, Lars Eckardt   +9 more
doaj   +3 more sources

Divergent Electrophysiologic Effects of Sacubitril in Digitalis- and Pinacidil-Related Shortened Repolarization: Experimental Evidence for Harmful Effects of Digitalis Glycosides [PDF]

Pharmaceutics
Background: Recent studies reported an abbreviation of cardiac repolarization induced by sacubitril. Thus, the purpose of this study was to evaluate the electrophysiologic effects of sacubitril in the presence of drugs that shorten the QT interval ...
Christian Ellermann, Carlo Mengel, Julian Wolfes, Felix K. Wegner, Benjamin Rath, Florian Reinke, Lars Eckardt, Gerrit Frommeyer   +7 more
doaj   +4 more sources

Variation in the chemical profiles of three foxglove species in the central Balkans [PDF]

Frontiers in Plant Science, 2023
The aim of this study was to determine intra- and interspecies variation in the qualitative and quantitative composition of methanol-soluble metabolites in the leaves of three Digitalis species (D. lanata, D. ferruginea, and D.
Uroš Gašić, Tijana Banjanac, Branislav Šiler, Jelena Božunović, Milica Milutinović, Neda Aničić, Slavica Dmitrović, Marijana Skorić, Jasmina Nestorović Živković, Luka Petrović, Miloš Todorović, Suzana Živković, Dragana Matekalo, Biljana Filipović, Tamara Lukić, Danijela Mišić   +15 more
doaj   +2 more sources

Analysis of Upper Gastrointestinal Adverse Events Associated with Oral Anticoagulants and Potential Drug Interactions with Cardiovascular Drugs: Exploratory Study Using FDA Adverse Event Reporting System [PDF]

Pharmaceuticals
Background: This study aimed to evaluate the risk of upper gastrointestinal (UGI) adverse events (AEs) associated with oral anticoagulants (OACs) and identify potential interactions with cardiovascular (CV) drugs. Methods: Individual case safety reports (
Seunghyun Cheon, Jiyeon Park, Dosol Oh, Young Seo Kim, Jee-Eun Chung   +4 more
doaj   +2 more sources

Clinical observation of esculin and digitalisglycosides eye drops with 0.3% sodium hyaluronate eye drops for dry eye disease: a randomized controlled trial [PDF]

Scientific Reports
Dry eye disease (DED) is a common ocular surface disorder. Esculin and digitalis possess anti-inflammatory and anti-oxidant properties, which may benefit patients with DED.
Yinghui Wang, Jiahao Yuan, Ya Wen, Siyuan Li, Lei Tian, Ying Jie   +5 more
doaj   +2 more sources

Comparative Photosynthetic Induction Reveals Stomatal Limitation and Reduced Efficiency in Digitalis purpurea Versus Cucumis sativus [PDF]

Biology
Digitalis purpurea, valued for its cardiotonic glycosides, remains an important medicinal species. Optimizing cultivation to enhance photosynthetic efficiency is critical for improving both biomass accumulation and metabolite yield.
Yunmin Wei, Xiaohong Xiang, Wei Jin, Haifeng Xiong, Lihong Tan   +4 more
doaj   +2 more sources

Production of cadiotonic glycosides in Digitalis purpurea using temporary immersion systems

Biotecnología Vegetal, 2005
Digitalis purpurea, is an example of cardiotonic drug. Digoxin and digitoxin are glycosides produced by this plant which are cardiac stimulants with a wide use in the treatment of heart problems.
Naivy Pérez-Alonso, Elio Jiménez, Dirk Wilken, André Gerth, Annett Jähn, Horst-Michael Nitzsche, Gerhard Kerns   +6 more
doaj   +1 more source

From WGS to gels: Development and testing of PCR primers targeting toxic <i>Digitalis</i> in support of food safety. [PDF]

Appl Plant Sci
Abstract Premise This study capitalized on a library of single‐nucleotide polymorphisms created via whole genome sequencing (WGS) to develop and test a PCR assay for detecting toxic Digitalis species in food products. Complex foods can be difficult to analyze, but safeguarding consumer well‐being and public health necessitates that products regulated ...
Hunter ES, Fo S, Literman R, Uva RH, Wolny JL, Handy SM.   +5 more
europepmc   +2 more sources

Genome and Tissue-Specific Transcriptome of the Tropical Milkweed (<i>Asclepias curassavica</i>). [PDF]

Plant Direct
ABSTRACT Tropical milkweed (Asclepias curassavica) serves as a host plant for monarch butterflies (Danaus plexippus) and other insect herbivores that can tolerate the abundant cardiac glycosides that are characteristic of this species. Cardiac glycosides, along with additional specialized metabolites, also contribute to the ethnobotanical uses of A ...
Feng H, Zhang J, Powell AF, Buttelmann GL, Yang L, Yan E, Wang F, Broyles SB, Jander G, Strickler SR.   +9 more
europepmc   +2 more sources

Duckweeds: Model organisms for research on plant sterols and steroids. [PDF]

Plant Biol (Stuttg)
Duckweeds (Lemnaceae), the fastest‐growing angiosperms and promising vegan protein source, offer a powerful model to address key questions in plant physiology. This article highlights their potential for dissecting the biosynthesis and function of phytosterols, sterol conjugates, brassinosteroids, and specialized steroidal metabolites, such as ...
Klein J, Appenroth KJ, Sree KS.
europepmc   +2 more sources