Results 1 to 10 of about 117,299 (259)

Digitalis Therapy Is Associated With an Increased Risk of ICD Shock Delivery and Device Revision [PDF]

Annals of Noninvasive Electrocardiology
Background Digitalis glycosides are employed for rate control of atrial fibrillation and treatment of heart failure. Previous studies suggested potential harmful effects of digitalis therapy.
Gerrit Frommeyer, Philipp S. Lange, Thomas Kleemann, Christoph Stellbrink, Hüseyin Ince, Johannes Brachmann, Thorsten Lewalter, Matthias Hochadel, Jochen Senges, Lars Eckardt   +9 more
doaj   +3 more sources

Identification of key genes involved in secondary metabolite biosynthesis in Digitalis purpurea [PDF]

PLoS ONE, 2023
The medicinal plant Digitalis purpurea produces cardiac glycosides that are useful in the pharmaceutical industry. These bioactive compounds are in high demand due to ethnobotany’s application to therapeutic procedures.
Fatemeh Amiri, Ali Moghadam, Ahmad Tahmasebi, Ali Niazi   +3 more
doaj   +4 more sources

Divergent Electrophysiologic Effects of Sacubitril in Digitalis- and Pinacidil-Related Shortened Repolarization: Experimental Evidence for Harmful Effects of Digitalis Glycosides [PDF]

Pharmaceutics
Background: Recent studies reported an abbreviation of cardiac repolarization induced by sacubitril. Thus, the purpose of this study was to evaluate the electrophysiologic effects of sacubitril in the presence of drugs that shorten the QT interval ...
Christian Ellermann, Carlo Mengel, Julian Wolfes, Felix K. Wegner, Benjamin Rath, Florian Reinke, Lars Eckardt, Gerrit Frommeyer   +7 more
doaj   +3 more sources

Chromatographic Separation of Digitalis Glycoside [PDF]

Nature, 1956
SEVERAL of the constituents of Digitalis purpurea have been separated by paper partition chromatography, using ethylene glycol as the stationary phase and chloroform saturated with ethylene glycol as the mobile phase.
G. J. Rigby, D. M. Bellis
openalex   +3 more sources

Selectivity of digitalis glycosides for isoforms of human Na,K-ATPase. [PDF]

J Biol Chem, 2010
There are four isoforms of the α subunit (α1–4) and three isoforms of the β subunit (β1–3) of Na,K-ATPase, with distinct tissue-specific distribution and physiological functions.
Katz A, Lifshitz Y, Bab-Dinitz E, Kapri-Pardes E, Goldshleger R, Tal DM, Karlish SJ.   +6 more
europepmc   +2 more sources

Variation in the chemical profiles of three foxglove species in the central Balkans [PDF]

Frontiers in Plant Science, 2023
The aim of this study was to determine intra- and interspecies variation in the qualitative and quantitative composition of methanol-soluble metabolites in the leaves of three Digitalis species (D. lanata, D. ferruginea, and D.
Uroš Gašić, Tijana Banjanac, Branislav Šiler, Jelena Božunović, Milica Milutinović, Neda Aničić, Slavica Dmitrović, Marijana Skorić, Jasmina Nestorović Živković, Luka Petrović, Miloš Todorović, Suzana Živković, Dragana Matekalo, Biljana Filipović, Tamara Lukić, Danijela Mišić   +15 more
doaj   +2 more sources

"Cardiac glycosides"-quo vaditis?-past, present, and future? [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Up to date, digitalis glycosides, also known as “cardiac glycosides”, are inhibitors of the Na+/K+-ATPase. They have a long-standing history as drugs used in patients suffering from heart failure and atrial fibrillation despite their well-known narrow ...
Fender J, Klöcker J, Boivin-Jahns V, Ravens U, Jahns R, Lorenz K.   +5 more
europepmc   +2 more sources

Genome and Tissue-Specific Transcriptome of the Tropical Milkweed (<i>Asclepias curassavica</i>). [PDF]

Plant Direct
ABSTRACT Tropical milkweed (Asclepias curassavica) serves as a host plant for monarch butterflies (Danaus plexippus) and other insect herbivores that can tolerate the abundant cardiac glycosides that are characteristic of this species. Cardiac glycosides, along with additional specialized metabolites, also contribute to the ethnobotanical uses of A ...
Feng H, Zhang J, Powell AF, Buttelmann GL, Yang L, Yan E, Wang F, Broyles SB, Jander G, Strickler SR.   +9 more
europepmc   +2 more sources

Digitalis and strophanthus---cardiac glycosides [PDF]

Heart, 1998
Digitalis lanata is shown on the 35 dinar Yugoslavian stamp from a set of nine issued in 1957, which includes the deadly nightshade and the meadow saffron. In 1966 Bulgaria also issued a set of flower stamps with the 2 stotinki value showing Digitalis purpurea .
M. K. Davies, A Hollman
openalex   +4 more sources

Clinical observation of esculin and digitalisglycosides eye drops with 0.3% sodium hyaluronate eye drops for dry eye disease: a randomized controlled trial [PDF]

Scientific Reports
Dry eye disease (DED) is a common ocular surface disorder. Esculin and digitalis possess anti-inflammatory and anti-oxidant properties, which may benefit patients with DED.
Yinghui Wang, Jiahao Yuan, Ya Wen, Siyuan Li, Lei Tian, Ying Jie   +5 more
doaj   +2 more sources