The chemistry and biological activity of the Hyacinthaceae [PDF]
Covering: 1914 to 2012The Hyacinthaceae (sensu APGII), with approximately 900 species in about 70 genera, can be divided into three main subfamilies, the Hyacinthoideae, the Urgineoideae and the Ornithogaloideae, with a small fourth subfamily the ...
Abbas+400 more
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The study examines how environmental factors and dietary diversity influence the gut microbiome of the invasive European buff‐tailed bumblebee (Bombus terrestris) in Tasmania. We found that gut bacterial composition and diversity were significantly affected by annual precipitation, pasture percentage, temperature and interactions between pollen ...
Sabrina Haque+6 more
wiley +1 more source
Predicting and Manipulating Cardiac Drug Inactivation by the Human Gut Bacterium Eggerthella lenta [PDF]
Despite numerous examples of the effects of the human gastrointestinal microbiome on drug efficacy and toxicity, there is often an incomplete understanding of the underlying mechanisms. Here, we dissect the inactivation of the cardiac drug digoxin by the
Balskus, Emily Patricia+5 more
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Preliminary qualitative screening for cancer chemopreventive agents in Telfairia occidentalis Hook.f., Gnetum africanum Welw., Gongronema latifolium Benth. and Ocimum gratissimum L. from Nigeria [PDF]
The leaves of four plant foods commonly consumed in Nigeria namely Gnetum africanum (Igbo name: Ukazi), Gongronema latifolium (Igbo name: Utazi), Telfairia occidentalis (Igbo name: Ugu), Ocimum gratissimum (Igbo name: Nchoanwu), were each screened for ...
Iweala, E. E. J.
core
Stabilisation of Na,K-ATPase structure by the cardiotonic steroid ouabain [PDF]
Cardiotonic steroids such as ouabain bind with high affinity to the membrane-bound cation-transporting P-type Na,K-ATPase, leading to complete inhibition of the enzyme.
Abdul-Gader+30 more
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A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues
A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine
Arturo San Feliciano+2 more
doaj +1 more source
Cardiac Calcitropes, Myotropes, and Mitotropes: JACC Review Topic of the Week. [PDF]
The term "inotrope" is familiar and intimately connected with pharmaceuticals clinically used for treatment of low cardiac output with cardiogenic shock.
Adams, KF+7 more
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Carbohydrate Synthesis is Entering the Data‐Driven Digital Era
The outcome of glycosylations, essential for glycochemistry, is difficult to predict due to its intricate mechanism and the influence of protective groups. Recent advances illustrate that integrating digital tools like automation, computational modelling, and data management drives progress in the carbohydrate synthesis field.
Eric T. Sletten+3 more
wiley +1 more source
Production of cadiotonic glycosides in Digitalis purpurea using temporary immersion systems
Digitalis purpurea, is an example of cardiotonic drug. Digoxin and digitoxin are glycosides produced by this plant which are cardiac stimulants with a wide use in the treatment of heart problems.
Naivy Pérez-Alonso+6 more
doaj
Colored floaters as a manifestation of digoxin toxicity
Purpose: Since its report in one patient more than 70 years ago, digitalis-induced colored muscae volitantes have not surfaced again in the literature. We report here a case of digoxin induced colored floaters. Observations: An 89-year-old man on 0.25 mg
Lynn Shi, Linus D. Sun, Jeffrey G. Odel
doaj +1 more source