Results 61 to 70 of about 6,589 (233)
European Journal of Heart Failure, Volume 27, Issue 7, Page 1224-1233, July 2025.Effects of digitoxin compared to placebo on efficacy and safety in patients with heart failure and reduced ejection fraction (HFrEF). Primary endpoint: time to all‐cause death and first hospitalization for worsening heart failure (whatever occurs first). ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNI, angiotensin
Udo Bavendiek +144 more
wiley +1 more source
Toxic plants and companion animals. [PDF]
, 2009 Poisoning by substances of plant origin is unusual in both dogs and cats, yet it is possible; as many veterinarians do not know which plants can contain toxic active principles, the possibility of intoxication by ornamental plants commonly used to ...
SEVERINO, LORELLA
core +1 more source
Characterisation of Na/K-ATPase, its isoforms, and the inotropic response to ouabain in isolated failing human hearts [PDF]
, 2017 Objective: The aim was to determine whether failing human hearts have increased sensitivity to the inotropic and toxic effects of ouabain, and to examine alterations in Na/K-ATPase that might explain the observed higher ouabain sensitivity.
Gradoux, Nathalie +7 more
core
Prolongation of AV nodal refractoriness by Ruta graveolens in isolated rat hearts [PDF]
, 2008 Objectives: To evaluate concentration-dependent effects of total extract of Rusta graveolens and its purified alkaloid fraction on the nodal basic and functional properties.
Golalipour, M.J. +4 more
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Carbohydrate Synthesis is Entering the Data‐Driven Digital Era
Chemistry – A European Journal, Volume 31, Issue 27, May 14, 2025.The outcome of glycosylations, essential for glycochemistry, is difficult to predict due to its intricate mechanism and the influence of protective groups. Recent advances illustrate that integrating digital tools like automation, computational modelling, and data management drives progress in the carbohydrate synthesis field.
Eric T. Sletten +3 more
wiley +1 more source
BMC Genomics, 2012 Background Digitalis purpurea is an important ornamental and medicinal plant. There is considerable interest in exploring its transcriptome. Results Through high-throughput 454 sequencing and subsequent assembly, we obtained 23532 genes, of which 15626 ...
Wu Bin +7 more
doaj +1 more source
Evaluating the cancer therapeutic potential of cardiac glycosides [PDF]
, 2014 Cardiac glycosides, also known as cardiotonic steroids, are a group of natural products that share a steroid-like structure with an unsaturated lactone ring and the ability to induce cardiotonic effects mediated by a selective inhibition of the Na(+)/K(+)
Burgos Morón, Estefanía +5 more
core +3 more sources
Digitálicos: los resultados del DIG en el siglo XXI [PDF]
, 2010 After the report that there was no statistical significance in the general mortality of the DIG study, the indication of digoxin in the treatment regimens for congestive heart failure (CHF) drastically decreased.
Helber, Izo, Tucci, Paulo José Ferreira
core +4 more sources
eFood, Volume 6, Issue 2, April 2025.The plant's bark is rich in polyphenols, particularly gallic acid and ellagic acid derivatives, which are powerful antioxidants. These antioxidants can protect cells from oxidative stress and may help prevent degenerative diseases. Additionally, Terminalia arjuna contains triterpenoids like arjunolic acid and arjunic acid, which have various ...
Hafsa Tahir +13 more
wiley +1 more source
Medicinal Plants: A Public Resource for Metabolomics and Hypothesis Development
Metabolites, 2012 Specialized compounds from photosynthetic organisms serve as rich resources for drug development. From aspirin to atropine, plant-derived natural products have had a profound impact on human health.
Eve Syrkin Wurtele +10 more
doaj +1 more source