CdgC, a Cyclic-di-GMP Diguanylate Cyclase of Azospirillum baldaniorum Is Involved in Internalization to Wheat Roots. [PDF]
Sierra Cacho D +5 more
europepmc +2 more sources
Interaction between the type 4 pili machinery and a diguanylate cyclase fine-tune c-di-GMP levels during early biofilm formation. [PDF]
Webster SS +4 more
europepmc +3 more sources
Shigella flexneri Diguanylate Cyclases Regulate Virulence
The intracellular human pathogen Shigella causes dysentery, resulting in as many as one million deaths per year. Currently, there is no approved vaccine for the prevention of shigellosis, and the incidence of antimicrobial resistance among Shigella species is on the rise.
Ruchi Ojha +3 more
openalex +4 more sources
Diguanylate Cyclase Activation: It Takes Two [PDF]
Characterization of an activated diguanylate cyclase reported in this issue of Structure by Wassmann et al. (2007) reveals how phosphorylation promotes dimerization necessary for synthesis of the second messenger c-di-GMP, establishes the catalytic mechanism, and identifies a widely conserved mode of product inhibition.
Ann Stock
openalex +2 more sources
Structural basis for activation of a diguanylate cyclase required for bacterial predation in Bdellovibrio [PDF]
The initiation of prey invasion by the predatory bacterium Bdellovibrio bacteriovorus is governed by the activity of the diguanlylate cyclase DgcB. Here the authors show that the stimulus regulating DgcB activity is a phosphopeptide derived from DgcB ...
Richard W. Meek +3 more
doaj +2 more sources
Comparative analysis of diguanylate cyclase and phosphodiesterase genes in
Background Klebsiella pneumoniae can be found in environmental habitats as well as in hospital settings where it is commonly associated with nosocomial infections.
Cruz Diana P +4 more
doaj +3 more sources
BolA Is Required for the Accurate Regulation of c-di-GMP, a Central Player in Biofilm Formation [PDF]
The bacterial second messenger cyclic dimeric GMP (c-di-GMP) is a nearly ubiquitous intracellular signaling molecule involved in the transition from the motile to the sessile/biofilm state in bacteria.
Ricardo N. Moreira +6 more
doaj +4 more sources
Genomic Island-Encoded Diguanylate Cyclase from Vibrio alginolyticus Regulates Biofilm Formation and Motility in Pseudoalteromonas. [PDF]
Cai T +7 more
europepmc +3 more sources
Kiwifruit bacterial canker (KBC), caused by Pseudomonas syringae pv. actinidiae (Psa), poses a severe threat to the global kiwifruit industry, highlighting the urgent need to elucidate its pathogenic mechanisms. Cyclic diguanylate monophosphate (c-di-GMP)
Yudi Wang +7 more
doaj +2 more sources
Identification of Small-Molecule Modulators of Diguanylate Cyclase by FRET-Based High-Throughput Screening. [PDF]
Christen M +7 more
europepmc +3 more sources

