Results 61 to 70 of about 5,940 (209)

Role of small colony variants in persistence of Pseudomonas aeruginosa infections in cystic fibrosis lungs [PDF]

, 2015
Jacob G Malone1,21John Innes Centre, Norwich, UK; 2School of Biological Sciences, University of East Anglia, Norwich, UKAbstract: Pseudomonas aeruginosa is an opportunistic pathogen that predominates during the later stages of cystic fibrosis (CF) lung ...
Malone, Jacob
core   +2 more sources

New insights into Legionella pneumophila biofilm regulation by c-di-GMP signaling [PDF]

, 2016
The waterborne pathogen Legionella pneumophila grows as a biofilm, freely or inside amoebae. Cyclic-di-GMP (c-di-GMP), a bacterial second messenger frequently implicated in biofilm formation, is synthesized and degraded by diguanylate cyclases (DGCs) and
Allombert, Julie, Doublet, Patricia, Lajoie Halova, Barbora, Pécastaings, Sophie, Roques, Christine, Vianney, Anne   +5 more
core   +3 more sources

Diguanylate Cyclases Control Magnesium-Dependent Motility ofVibrio fischeri [PDF]

Journal of Bacteriology, 2006
ABSTRACTFlagellar biogenesis and hence motility ofVibrio fischeridepends upon the presence of magnesium. In the absence of magnesium, cells contain few or no flagella and are poorly motile or nonmotile. To dissect the mechanism by which this regulation occurs, we screened transposon insertion mutants for those that could migrate through soft agar ...
Therese M, O'Shea, Adam H, Klein, Kati, Geszvain, Alan J, Wolfe, Karen L, Visick   +4 more
openaire   +2 more sources

The BDSF quorum sensing receptor RpfR regulates Bep exopolysaccharide synthesis in Burkholderia cenocepacia via interaction with the transcriptional regulator BerB

npj Biofilms and Microbiomes, 2022
The polysaccharide Bep is essential for in vitro biofilm formation of the opportunistic pathogen Burkholderia cenocepacia. We found that the Burkholderia diffusible signaling factor (BDSF) quorum sensing receptor RpfR is a negative regulator of the bep ...
Elisabeth Steiner, Rebecca E. Shilling, Anja M. Richter, Nadine Schmid, Mustafa Fazli, Volkhard Kaever, Urs Jenal, Tim Tolker-Nielsen, Leo Eberl   +8 more
doaj   +1 more source

Two-component systems required for virulence in Pseudomonas aeruginosa [PDF]

, 2017
This is the author accepted manuscript. The final version is available from Oxford University Press via the DOI in this record.Pseudomonas aeruginosa is a versatile opportunistic pathogen capable of infecting a broad range of hosts, in addition to ...
Francis, VI, Porter, SL, Stevenson, EC
core   +1 more source

The Diguanylate Cyclase GcbA Facilitates Pseudomonas aeruginosa Biofilm Dispersion by Activating BdlA [PDF]

Journal of Bacteriology, 2014
ABSTRACT Biofilm dispersion is a highly regulated process that allows biofilm bacteria to respond to changing environmental conditions and to disseminate to new locations. The dispersion of biofilms formed by the opportunistic pathogen Pseudomonas aeruginosa is known to ...
Olga Petrova, Kathryn E. Cherny, Karin Sauer   +2 more
openalex   +3 more sources

The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, [PDF]

, 2014
In nature, the Lyme disease spirochete Borrelia burgdorferi cycles between the unrelated environments of the Ixodes tick vector and mammalian host. In order to survive transmission between hosts, B.
Adams, Adams, Albright, Amikam, Andrade, Armitage, Barends, Barrett, Beier, Benach, Berg, Bian, Blevins, Boardman, Bobrov, Boehm, Boylan, Brisson, Brooks, Brown, Burgdorfer, Burtnick, Caimano, Caimano, Caimano, Carroll, Carroll, Casjens, Chae, Chang, Chang, Charon, Chatterjee, Christen, Christen, Christen, Cotter, Duerig, Dunham-Ems, Fang, Fazli, Fisher, Fraser, Freedman, Fries, Galperin, Galperin, Galperin, Girgis, Goldman, Groshong, Habazettl, HajduÅ¡ek, Hammer, He, He, Hengge, Hickman, Hickman, Hyde, Hyde, Hübner, Jenal, Katona, Kazmierczak, Kim, Ko, Kostick, Krasteva, Kuehn, Kulasekara, Lai, Lane, Lee, Levine, Li, Luo, Maes, Massie, Mather, McCarthy, Merighi, Monds, Moriarty, Motaleb, Motaleb, Nickels, Norman, Ojaimi, Ojaimi, Ostfeld, Ouyang, Ouyang, Ouyang, Ouyang, Pappas, Paul, Paul, Pazy, Pesavento, Pitzer, Pratt, Radolf, Revel, Rogers, Ross, Russell, Ryan, Ryan, Ryan, Ryan, Ryan, Ryjenkov, Ryjenkov, Römling, Römling, Römling, Römling, Samuels, Samuels, Schirmer, Schmidt, Schmidt, Seshu, Silversmith, Smith, Sommerfeldt, Sonenshine, Sonenshine, Stelitano, Stock, Sudarsan, Sultan, Sultan, Sze, Sze, Tal, Tam, Tamayo, Tamayo, Tamayo, Tao, Thomas, Tilly, Tokarz, Trappetti, Tsao, Tuckerman, Tuckerman, Vvedenskaya, Weber, West, Wolfe, Xu, Yang, Yang, Yildiz, Yildiz, Zhang, Zorraquino   +159 more
core   +2 more sources

Natural diversity provides a broad spectrum of cyanobacteriochrome-based diguanylate cyclases

Plant Physiology, 2021
Abstract Cyanobacteriochromes (CBCRs) are spectrally diverse photosensors from cyanobacteria distantly related to phytochromes that exploit photoisomerization of linear tetrapyrrole (bilin) chromophores to regulate associated signaling output domains. Unlike phytochromes, a single CBCR domain is sufficient for photoperception.
Matthew Blain-Hartung, Nathan C. Rockwell, J. Clark Lagarias   +2 more
openaire   +2 more sources

Specific Control of Pseudomonas aeruginosa Surface-Associated Behaviors by Two c-di-GMP Diguanylate Cyclases

mBio, 2010
The signaling nucleotide cyclic diguanylate (c-di-GMP) regulates the transition between motile and sessile growth in a wide range of bacteria. Understanding how microbes control c-di-GMP metabolism to activate specific pathways is complicated by the ...
Judith H. Merritt, Dae-Gon Ha, Kimberly N. Cowles, Wenyun Lu, Diana K. Morales, Joshua Rabinowitz, Zemer Gitai, George A. O’Toole   +7 more
doaj   +1 more source

Diguanylate cyclase activity of the Mycobacterium leprae T cell antigen ML1419c. [PDF]

Microbiology (Reading), 2016
The second messenger, bis-(3',5')-cyclic dimeric guanosine monophosphate (cyclic di-GMP), is involved in the control of multiple bacterial phenotypes, including those that impact host-pathogen interactions. Bioinformatics analyses predicted that Mycobacterium leprae, an obligate intracellular bacterium and the causative agent of leprosy, encodes three ...
Rotcheewaphan S, Belisle JT, Webb KJ, Kim HJ, Spencer JS, Borlee BR.   +5 more
europepmc   +3 more sources