Malaria is still an endemic disease in Africa, with many imported cases in Europe. The standard treatment is intravenous artesunate for severe malaria and oral artemisinin-based combination therapy (ACT) for uncomplicated malaria.
Marion Louvois +12 more
doaj +1 more source
Efficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium vivax malaria in endemic countries: meta-analysis of randomized controlled studies [PDF]
Background: This study aimed to synthesize available evidence on the efficacy of dihydroartemisinin-piperaquine (DHP) in treating uncomplicated Plasmodium vivax malaria in people living in endemic countries.
Cho Naing (492196) +27 more
core +1 more source
Role of Anopheles stephensi Mosquitoes in Malaria Outbreak, Djibouti, 2019
Anopheles stephensi mosquitoes share urban breeding sites with Aedes aegypti and Culex quinquefasciatus mosquitoes in the Republic of Djibouti. We present evidence that A.
Vincent Pommier de Santi +14 more
doaj +1 more source
Falsified drugs are of serious concern to public health worldwide, particularly for developing countries where quality control of drugs is inefficient.
Moussa Yabré +6 more
doaj +1 more source
Intermittent preventive treatment with dihydroartemisinin-piperaquine (DP) is protective in children against malaria. Here, the authors analyze plasma drug concentration, malaria incidence, and drug resistance markers from a clinical trial in Uganda and ...
Erika Wallender +15 more
doaj +1 more source
Prediction of Improved Antimalarial Chemoprevention with Weekly Dosing of Dihydroartemisinin-Piperaquine [PDF]
ABSTRACT Intermittent preventive treatment (IPT) is used to reduce malaria morbidity and mortality, especially in vulnerable groups such as children and pregnant women. IPT with the fixed dose combination of piperaquine (PQ) and dihydroartemisinin (DHA) is being evaluated as a potential mass treatment to control and eliminate artemisinin ...
Jesmin Permala +5 more
openaire +4 more sources
Tafenoquine co-administered with dihydroartemisinin-piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study. [PDF]
Background: Tafenoquine, co-administered with chloroquine, is approved for the radical cure (prevention of relapse) of Plasmodium vivax malaria. In areas of chloroquine resistance, artemisinin-based combination therapies are used to treat malaria.
Sutanto I +28 more
europepmc +2 more sources
Dihydroartemisinin-piperaquine for treating uncomplicated Plasmodium falciparum malaria [PDF]
The World Health Organization (WHO) recommends Artemisinin-based Combination Therapy (ACT) for treating uncomplicated Plasmodium falciparum malaria. This review aims to assist the decision-making of malaria control programmes by providing an overview of the relative effects of dihydroartemisinin-piperaquine (DHA-P) versus other recommended ACTs.To ...
Zani, Babalwa +4 more
openaire +2 more sources
Prospective observational study to evaluate the clinical safety of the fixed-dose artemisinin-based combination Eurartesim® (dihydroartemisinin/piperaquine), in public health facilities in Burkina Faso, Mozambique, Ghana, and Tanzania. [PDF]
BACKGROUND: The World Health Organization recommends artemisinin-based combination (ACT) for the treatment of uncomplicated malaria. Post-licensure safety data on newly registered ACT is critical for evaluating their risk/benefit profile in malaria ...
Abdulla, Salim +20 more
core +1 more source
Dihydroartemisinin–piperaquine holds promise as an option for malaria prevention in pregnancy [PDF]
Commentary on : Kakuru A, Jagannathan P, Muhindo MK, et al. Dihydroartemisinin-piperaquine for the prevention of malaria in pregnancy. N Engl J Med 2016;374:928–39.[OpenUrl][1][CrossRef][2][PubMed][3] Malaria in pregnancy has devastating consequences for mother and fetus.
Hill, Jenny, ter Kuile, Feiko O
openaire +4 more sources

