Background: The present study was formulated in order to determine polÂymorphism of dihydropteroate synthetase gene (dhps) of Plasmodium vivax (P. vivax) in Hormozgan Province, southern Iran and mutations at codons 382, 383, 512, 553, and 585 associated ...
Somayeh MAGHSOODLOORAD+7 more
doaj
In order to increase the tissue level of tetrahydrobiopterin (BH4 ) , supplementation with 6R-tetrahydrobiopterin (6RBH4) has been widely employed. In this work, the profile of BH4 accumulation was compared between the liver and the small intestine after
Sawabe Keiko+3 more
doaj +1 more source
Electron Transfer-oxy Radical Mechanism for Anti-cancer Agents: 9-anilinoacridines [PDF]
A possible mode of action involving electron transfer is advanced for the 9- anilinoacridines. The mechanism entails formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R.+2 more
core +1 more source
Folate Reductase and Specific Dihydrofolate Reductase Activities of the Amethopterin-Sensitive Streptococcus faecium var. durans [PDF]
A Albrecht, Dorris J. Hutchison
openalex +1 more source
Short report: molecular markers associated with Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in the Democratic Republic of Congo. [PDF]
Sulfadoxine-pyrimethamine (SP) is the first line antimalarial treatment in the Democratic Republic of Congo. Using polymerase chain reaction, we assessed the prevalence of mutations in the dihydrofolate reductase (dhfr) (codons 108, 51, 59) and ...
Bonnet, M+5 more
core +2 more sources
Dihydrofolate reductase: low-resolution mass-spectrometric analysis of an elastase digest as a sequencing tool [PDF]
Howard R. Morris+5 more
openalex +1 more source
Allosteric regulatory control in dihydrofolate reductase is revealed by dynamic asymmetry. [PDF]
Kazan IC, Mills JH, Ozkan SB.
europepmc +1 more source
Control of synthesis of mRNA's for T4 bacteriophage-specific dihydrofolate reductase and deoxycytidylate hydroxymethylase [PDF]
H Witmer, Anna Baros, D Ende, M Dosmar
openalex +1 more source
Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes. [PDF]
Randal J. Kaufman+2 more
openalex +1 more source