Results 71 to 80 of about 5,442 (212)
, 2016 An Australian marine sediment-derived isolate, Nocardiopsis sp. (CMB-M0232), yielded a new class of prenylated diketopiperazine, indicative of the action of a uniquely regioselective diketopiperazine indole prenyltransferase.
Robert J. Capon (210563) +3 more
core +1 more source
Synthesis of Cross-linkable 2,5-Diketopiperazine Derivatives [PDF]
, 2015 Synthesis of cross-linkable diketopiperadine derivatives is described. Cross-linkable a-amino acid methyl esters were subjected to peptide synthesis with Boc-protected glycine or L-tyrosine. No protection of cross-linkable functional groups (catechol and
Hashimoto, Makoto +6 more
core +1 more source
Marine Drugs, 2018 One new bisabolane sesquiterpene, bisabolan-1,10,11-triol (1), one new norbisabolane sesquiterpene, 12-nor-11-acetoxybisabolen-3,6,7-triol (2), two new naturally occurring monoterpenes, (7S)- and (7R)-1-hydroxy-3-p-menthen-9-oic acids (3 and 4), one new ...
Yin-Ping Song +4 more
doaj +1 more source
The Journal of Organic Chemistry, 2017 Aza-diketopiperazines (aza-DKPs) represent an underprivileged motif obtained by scaffold hopping of 2,5-diketopiperazines (2,5-DKPs). Herein, we compare the synthesis and the structural and physicochemical properties of aza-DKP 4 vs 2,5-DKP 7. Thus, X-ray and 1H NMR studies show that aza-DKP 4 is a rigid and nonflat scaffold like the 2,5-DKP 7 ...
Regenass, Pierre +7 more
openaire +5 more sources
Endophytic Fungi Natural Factories of Novel Bioactive Compounds
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev +18 more
wiley +1 more source
Enantioselective synthesis of 2,2,5-Tri- and 2,2,5,5-tetrasubstituted tetrahydrofurans and synthesis of diketopiperazine containing natural products [PDF]
, 2013 textA chiral vinyl sulfoxide has been developed that undergoes highly diastereoselective Diels−Alder cycloadditions with various substituted furans in excellent yield.
Benjamin, Noah Meyer
core
Unsaturated Diketopiperazine Intermediate
, 2016 Unnatural aromatic amino acids are useful tools in drug discovery, since their insertion in bioactive peptide sequences can change the side chains spatial orientation, the backbone conformation and above all, their bioactivity.
Simone Carradori +13 more
core +1 more source
Metabolites, 2019 Actinomycetes are powerhouses of natural product biosynthesis. Full realization of this biosynthetic potential requires approaches for recognizing novel metabolites and determining mediators of metabolite production.
Jordan Carey +5 more
doaj +1 more source
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.Two new asperfurans (1 and 2) and 23 known compounds from marine Aspergillus flavus were characterized by NMR, HRESIMS, DP4+, and ECD. Asperfuran (3) potently inhibited RSL3‐induced ferroptosis (EC50 = 0.81 µM). ABSTRACT Marine microorganisms represent a prolific reservoir of chemically diverse natural products endowed with considerable therapeutic ...
Chun‐Xiu Wang +4 more
wiley +1 more source
Re‐evaluation of salt of aspartame‐acesulfame (E 962) as food additive
EFSA Journal, Volume 24, Issue 9, September 2026.Abstract The present opinion deals with the re‐evaluation of salt of aspartame‐acesulfame (E 962) as a food additive. The Panel considered that upon ingestion, E 962 dissociates into aspartame and acesulfame ions which correspond to those of the authorised sweeteners aspartame (E 951) and acesulfame K (E 950). The Panel therefore assessed the safety of
EFSA Panel on Food Additives and Flavourings (FAF) +34 more
wiley +1 more source