Chemical Constituents and Anticancer Activities of Marine-Derived Fungus Trichoderma lixii
MoleculesThe fungal genus Trichoderma is a rich source of structurally diverse secondary metabolites with remarkable pharmaceutical properties. The chemical constituents and anticancer activities of the marine-derived fungus Trichoderma lixii have never been ...
Natchanun Sirimangkalakitti +5 more
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A Metabolomic Study of the Variability of the Chemical Composition of Commonly Consumed Coffee Brews
Metabolites, 2019 Coffee drinking has been associated with a lower risk of certain chronic diseases and overall mortality. Its effects on disease risk may vary according to the type of coffee brew consumed and its chemical composition.
Joseph A. Rothwell +6 more
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Nojirimycin Based 2,5-Diketopiperazines
Synthetic Communications, 2019 2,5-Diketopiperazines were prepared and characterized where one of the amino acids is (2S,3R,4R,5S)-3,4,5-trihydroxypipecolic acid. The protected pipecolic acid was synthesized from a selectively protected deoxynojirimycin derivative. The ring closure to give the diketopiperazines, from the dipeptides, was performed by nucleophilic attack of the amino ...
openaire +1 more source
BITTER PEPTIDES, OCCURRENCE AND STRUCTURE [PDF]
, 2017 The bitter taste of many protein rich foods resides in the peptide fraction. 61 bitter tasting peptides, isolated from natural systems, and 145 bitter tasting synthetic peptides are reviewed.
GUIGOZ, Y., SOLMS, J.
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Direct amidation of unprotected amino acids using B(OCH2CF3)3 [PDF]
, 2016 A commercially available borate ester, B(OCH2CF3)3, can be used to achieve protecting-group free direct amidation of α-amino acids with a range of amines in cyclopentyl methyl ether.
Badland, M +6 more
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Radical-mediated Dimerization and Oxidation Reactions for the Synthesis of Complex Alkaloids
CHIMIA, 2012 Concise and general strategies for radical-based dimerization of cyclotryptamine and cyclotryptophan derivatives in addition to radical-based oxidation of structurally complex diketopiperazines are discussed.
Stephen P. Lathrop +2 more
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Sejtadhéziós peptidszármazékok szintézise daganatgátlás céljából = Synthesis of cell adhesion peptide derivatives as potential cytostatic agents [PDF]
, 2007 A sejtadhéziós integrin receptorok általános liganduma az RGD peptidszekvencia, a receptorszelektivitást döntően a molekulában levő savas és bázikus csoport közötti távolság szabja meg.
Mihala, Nikolett +1 more
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Beilstein Journal of Organic Chemistry, 2018 A practical three-step protocol for the assembly of triazolobenzodiazepine-fused diketopiperazines and hydantoins has been developed. The synthesis of these tetracyclic ring systems was initiated by an Ugi reaction, which brought together all necessary ...
Robby Vroemans +7 more
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Antarctic sponge associated microbial chemistry with biomedical relevance– the need for ecologically driven studies [PDF]
, 2016 Sponges are known to be a rich source of structurally diverse bioactive natural products, accounting for approximately one third of the 25,000 novel marine natural products discovered to date.
Buchholz, Holger H. +1 more
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Diastereoselective Hydrogenation in the Preparation of Fine Chemicals [PDF]
, 2018 Heterogeneous catalytic diastereoselective hydrogenation is reviewed with a special emphasis on its application in the preparation of fine ...
Kukula, Pavel, Prins, Roel
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