Results 61 to 70 of about 100,813 (283)

Combined analysis of 16S rDNA sequencing and metabolomics to find biomarkers of drug-induced liver injury

open access: yesScientific Reports, 2023
Drug induced liver injury (DILI) is a kind of liver dysfunction which caused by drugs, and gut microbiota could affect liver injury. However, the relationship between gut microbiota and its metabolites in DILI patients is not clear.
Kaini He   +4 more
doaj   +1 more source

Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2023
Drug-induced liver injury (DILI) is a liver condition caused by any drug or toxic substance. The spectrum of DILI manifestations can range from asymptomatic elevation of liver enzymes to acute liver failure.
Carina Silva   +4 more
doaj   +1 more source

Quantitative Systems Toxicology Predicts Ivacaftor‐Induced Oxidative Stress Contributes to CFTR Modulator Hepatotoxicity

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cystic fibrosis (CF) is a chronic hereditary disease that affects tens of thousands of people worldwide. The introduction of CFTR modulator therapies such as elexacaftor/tezacaftor/ivacaftor (ETI) has significantly improved the quality of life of people with CF.
Alan Shi   +3 more
wiley   +1 more source

Üniversitelerdeki Türk Dili Derslerinin Dünü, Bugünü, Yarını (Sorunlar-Çözüm Önerileri) Çalıştayı

open access: yesSkad, 2023
Bu yazı Sakarya Üniversitesi Rektörlük-Türk Dili Bölümü tarafından 26 Eylül 2023 tarihinde yapılan "Üniversitelerdeki Türk Dili derslerinin Dünü, Bugünü, Yarını (Sorunlar-Çözüm Önerileri)" adlı çalıştayı konu almaktadır.
Hürdünya Şahan, Özlem Düzlü
doaj  

A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel. [PDF]

open access: yes, 2019
Pexidartinib (PLX3397) is a small molecule tyrosine kinase and colony-stimulating factor-1 inhibitor with FDA breakthrough therapy designation for tenosynovial giant-cell tumor, and currently under study in several other tumor types, including breast ...
Chien, A Jo   +5 more
core  

Adverse drug reaction and organ damage: the liver [PDF]

open access: yes, 2016
Drug-induced liver injury (Dili) is among the most challenging acute or chronic liver conditions to be handled by physicians. Despite its low incidence in the general population, Dili is a frequent cause of acute liver failure.
LICATA, Anna
core   +1 more source

Identification of average molecular weight (AMW) as a useful chemical descriptor to discriminate liver injury-inducing drugs.

open access: yesPLoS ONE, 2021
Drug-induced liver injury (DILI) is one of major causes of discontinuing drug development and withdrawing drugs from the market. In this study, we investigated chemical properties associated with DILI using in silico methods, to identify a ...
Yuki Shimizu   +6 more
doaj   +1 more source

Urine metabolomics and microbiome analyses reveal the mechanism of anti-tuberculosis drug-induced liver injury, as assessed for causality using the updated RUCAM: A prospective study

open access: yesFrontiers in Immunology, 2022
BackgroundAnti-tuberculosis drug-induced liver injury (ATB-DILI) is one of the most common adverse reactions that brings great difficulties to the treatment of tuberculosis. Thus, early identification of individuals at risk for ATB-DILI is urgent.
Ming-Gui Wang   +4 more
doaj   +1 more source

The Web-Based Usability Heuristic Survey Supports User Satisfaction

open access: yesIndonesian Journal of Information Systems, 2020
Competition between companies is now getting stronger strongly related to the company's mechanism in providing the services provided. Companies can build ways that can maintain customer loyalty.
Emanuel Wijayanto   +2 more
doaj   +1 more source

Food and nutrition security in Timor-Leste [PDF]

open access: yes, 2013
This report is a literature review on Food and Nutrition Security in Timor-Leste based on data from surveys conducted by the Timor-Leste National Statistics Directorate, as well as from national and international organizations working in Timor-Leste ...
Andersen, A.B., Pant, J., Thilsted, S.H.
core  

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