Results 61 to 70 of about 15,827 (239)

Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress

Cell Death and Disease, 2023
Drug-induced liver injury (DILI) is the leading cause of acute liver failure (ALF). Continuous and prolonged hepatic cellular oxidative stress and liver inflammatory stimuli are key signatures of DILI.
Tingting Luo, Suzhen Yang, Tianming Zhao, Hanlong Zhu, Chunyan Chen, Xiaoxiao Shi, Di Chen, Kai Wang, Kang Jiang, Dan Xu, Ming Cheng, Juan Li, Wenting Li, Weijun Xu, Lin Zhou, Mingzuo Jiang, Bing Xu   +16 more
doaj   +1 more source

Hepatic macrophages in drug-induced liver injury

Liver Research, 2019
Drug-induced liver injury (DILI) is a major public health concern. Intrinsic DILI, for example, acetaminophen overdose accounts for half of acute liver failure in the United States.
Zhao Shan, Cynthia Ju
doaj   +1 more source

National cross-sectional cluster survey of tuberculosis prevalence in Timor-Leste: a study protocol

BMJ Open
Introduction Timor-Leste has one of the world’s highest estimated tuberculosis (TB) incidences, yet the data which informs this estimate is limited and the true burden of TB disease is not known.
Joana Dias, Joshua Reginald Francis, Jennifer Yan, Christopher Lowbridge, Nelson Martins, Salvador Amaral, Tessa Oakley, Nevio Sarmento, Endang da Silva, Constantino Lopes, Josefina Clarinha Joao, Rofina Isabel Gusmão dos Santos, Sureshbabu Ramalingam, Lourenco da Costa Ico   +13 more
doaj   +1 more source

"Sılası Yitik" Bir Münzevi Ziya Osman Saba

Mukaddime, 2017
Beyhan Kanter tarafından kaleme alınan “Sılası Yitik” Bir Münzevi Ziya Osman Saba” adlı eser, Edebiyat Ortamı Yayınlarından çıkmıştır. Eser, “Sunuş”, “Hayatı” , “Eserleri” ve “Sonuç” bölümlerinden oluşur.
Şakire Balıkçı
doaj   +1 more source

Dili

, 2021
Dissertação de Mestrado em Arquitetura com a especialização em Arquitetura apresentada na Faculdade de Arquitetura da Universidade de Lisboa para obtenção do grau de Mestre.
openaire   +1 more source

Vanillin Modulates the Sedative Effect of Diazepam, Possibly Through GABAergic Interaction Pathways in Thiopental Sodium‐Induced Sleeping Mice

Food Safety and Health, Volume 4, Issue 1, Page 220-232, January 2026.
Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh, Md. Shimul Bhuia, Raihan Chowdhury, Md. Sakib Al Hasan, Most. Israt Jahan Oni, Imam Hossen Rakib, Mir Imran Alim, Jakia Sultana, Muhammad Torequl Islam   +8 more
wiley   +1 more source

Determination of the Lethal Concentrations of Two Phenolic Acid Derivatives Originated From the Edible Red Marine Macroalga (Bangia fuscopurpurea) Using the In Vivo Zebrafish Eleutheroembryo Model and Their In Silico Structure–Toxicity Relationship Study

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
This study compared the predicted and experimental toxicity of two phenolic acid derivatives (HBP2 and HBP3) from the edible macroalga Bangia fuscopurpurea. HBP2 exhibited greater in vivo safety and lower predicted toxicity risks in silico, whereas HBP3 displayed higher in vitro cytotoxicity in IMR‐32 cells, potentially associated with the ...
Shi‐Ying Huang, Guiling Li, Yi‐Jia Shih, Chang‐Wei Hsieh, Yun‐Sheng Lin, Jingwen Liu, Tao Sun, Chien‐Wei Feng   +7 more
wiley   +1 more source

Replicate Me if You Can: Assessing Measurement Reliability of Individual Differences in Reading Across Measurement Occasions and Methods

Cognitive Science, Volume 50, Issue 1, January 2026.
Abstract Psycholinguistic theories traditionally assume similar cognitive mechanisms across different speakers. However, more recently, researchers have begun to recognize the need to consider individual differences when explaining human cognition. An increasing number of studies have investigated how individual differences influence human sentence ...
Patrick Haller, Cui Ding, Maja Stegenwallner‐Schütz, David R. Reich, Iva Koncic, Silvia Makowski, Lena A. Jäger   +6 more
wiley   +1 more source

Identification and Characterization of Three Novel Biomarkers for Mixed/Cholestatic Drug‐Induced Liver Injury

Hepatology Research, Volume 56, Issue 1, Page 111-124, January 2026.
Three metabolites, pyroglutamylglycine (pyroGluGly), phenylalanine (Phe), and phenylalanyltryptophan (PheTrp), were identified as candidate DILI biomarkers. The serum concentrations of pyroGluGly, Phe, and PheTrp demonstrated a high differentiating ability in patients with mixed and cholestatic DILI compared with those in patients who recovered from ...
Kosuke Saito, Tatehiro Kagawa, Keiji Tsuji, Yuji Kumagai, Ken Sato, Shotaro Sakisaka, Naoya Sakamoto, Mitsuhiko Aiso, Shunji Hirose, Nami Mori, Toshio Uraoka, Kazuhide Takata, Koji Ogawa, Kazuhiko Mori, Motonobu Sato, Takayoshi Nishiya, Kazuhiko Takamatsu, Noriaki Arakawa, Takashi Izumi, Ruri Kikura‐Hanajiri, Yasuo Ohno, Yoshiro Saito, Hajime Takikawa   +22 more
wiley   +1 more source

Clinical Characteristics of Patients with Drug-induced Liver Injury

Chinese Medical Journal, 2017
Background: Drug is an important cause of liver injury and accounts for up to 40% of instances of fulminant hepatic failure. Drug-induced liver injury (DILI) is increasing while the diagnosis becomes more difficult.
Li-Xia Yang, Cheng-Yuan Liu, Lun-Li Zhang, Ling-Ling Lai, Ming Fang, Chong Zhang   +5 more
doaj   +1 more source