Results 71 to 80 of about 13,535 (197)

National cross-sectional cluster survey of tuberculosis prevalence in Timor-Leste: a study protocol

open access: yesBMJ Open
Introduction Timor-Leste has one of the world’s highest estimated tuberculosis (TB) incidences, yet the data which informs this estimate is limited and the true burden of TB disease is not known.
Joana Dias   +13 more
doaj   +1 more source

Disulfiram‐Induced Hepatotoxicity in a Patient With Alcohol Use Disorder: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Disulfiram can cause severe and potentially fatal hepatotoxicity, particularly in patients with preexisting liver disease. In Bhutan, where alcohol‐related liver disease represents a major public health burden and pharmacological options for relapse prevention remain limited, careful patient selection, hepatic assessment, and early monitoring ...
Sonam Wangchuk   +2 more
wiley   +1 more source

Wild Edible Plants in Angola: Diversity, Traditional Uses, Phytochemical Properties, and Socio‐Economic Potential

open access: yeseFood, Volume 7, Issue 4, August 2026.
Wild edible plants (WEP) in Angola: number of species recorded by family and their distribution ranges; four of the most used WEP: Tamarindus indica (Fabaceae), Carissa spinarum (Apocynaceae), Adansonia digitata (Malvaceae), and Vitex doniana (Lamiaceae).
Claudete Bastos   +4 more
wiley   +1 more source

Integrative GC–MS, FT‐IR, and Molecular Docking Analysis of Drimycarpus racemosus (Roxb.) Hook.f ex Marchand: In Vivo Analgesic and Antidiabetic Potential

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
GC–MS profiling of D. racemosus identified bioactive phytochemicals with promising molecular interactions through docking analysis. The methanolic extract demonstrated significant antinociceptive activity against acetic acid‐ and formalin‐induced pain and exhibited antidiabetic effects in streptozotocin‐induced diabetic Swiss albino mice, supporting ...
Md Sajib Ali   +7 more
wiley   +1 more source

3D Liver Fibrosis Models in Lab: A Novel Modality for Drug Screening

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Liver fibrosis is the common consequence of liver injury caused by a variety of chronic liver disorders. This condition leads to the development of more severe complications, particularly cirrhosis and hepatocellular carcinoma. Despite abundant studies, the fundamental cell and molecular mechanisms of liver fibrosis are still unknown.
Hani Keshavarz Alikhani   +10 more
wiley   +1 more source

Emerging Immune‐Based Therapeutic Strategies in Hepatocellular Carcinoma

open access: yesLiver International, Volume 46, Issue 8, August 2026.
ABSTRACT Hepatocellular carcinoma (HCC) remains a leading cause of cancer‐related mortality worldwide despite recent advances in systemic therapy. The introduction of immune checkpoint inhibitors has substantially expanded treatment options for advanced disease; however, durable responses are observed only in a subset of patients.
Janine Kah   +2 more
wiley   +1 more source

Gut microbiota causally affects drug-induced liver injury via plasma metabolites: a Mendelian randomization study

open access: yesFrontiers in Microbiology
BackgroundThe gut microbiota and plasma metabolites play important roles in the progression of drug-induced liver injury (DILI). We investigated the causal associations between the gut microbiota, plasma metabolome, and DILI.MethodsThe summary data for ...
Haoshuang Fu   +3 more
doaj   +1 more source

InterDILI: interpretable prediction of drug-induced liver injury through permutation feature importance and attention mechanism

open access: yesJournal of Cheminformatics
Safety is one of the important factors constraining the distribution of clinical drugs on the market. Drug-induced liver injury (DILI) is the leading cause of safety problems produced by drug side effects.
Soyeon Lee, Sunyong Yoo
doaj   +1 more source

Gut microbiota and metabolomic profiles of tacrolimus-induced DILI in renal transplant recipients: a population-based case control study

open access: yesBMC Microbiology
Background In clinical practice, cases of drug-induced liver injury (DILI) often occur in renal transplant recipients treated with tacrolimus (Tac) as an immunosuppressive therapy.
Guolin Li   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy