Results 91 to 100 of about 14,328 (204)

Targeting a Leukemia‐Relevant Protein–Protein Interface: N‐Aryl Anthranilic Acids as Disruptors of the c‐Myb–CBP/p300 KIX Interaction

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
An integrated virtual screening, MD/MM‐PBSA, and MST workflow identifies N‐aryl anthranilic acids as disruptors of the leukemia‐relevant c‐Myb–CBP/p300 KIX interface. Hit C3 destabilizes the complex and inhibits c‐Myb–KIX binding more potently than Naphthol AS‐E phosphate.
Haifa E. Alfassam, Emadeldin M. Kamel, Sarah I. Othman, Hanan M. Alharbi, Hassan A. Rudayni, Ahmed A. Allam, Al Mokhtar Lamsabhi   +6 more
wiley   +1 more source

BASIN DİLİ ÜZERİNE BAZI DİKKATLER

İletişim Kuram ve Araştırma Dergisi, 2014
Basın dilinin umumî dil içerisinde yazı dili ile konuşma dili arasında kendine mahsus yeri ve işlevi vardır. Bu yazıda basın dilinin ana dil içerisindeki yeri ve kendisi gibi standard dil içerisinde yer alan diğer alt ve üst dil şubeleriyle benzerlik ...
ersin özarslan
doaj   +2 more sources

ESKİ KİLİSE SLAV DİLİNİN (KİLİSE SLAVCASININ) ORTAYA ÇIKIŞI VE ÇAĞDAŞ RUS EDEBÎ DİLİ AÇISINDAN ÖNEMİ

Ankara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Dergisi
Herhangi bir dilin tarihi üzerine yapılan araştırmalar aslında o dili konuşan halklar tarihinin araştırılması anlamına gelmektedir. Bu hususta ‘‘ölü diller’’ olarak adlandırılan dillerin incelenmesi tarih uzmanına etnik ve kültürel özellikler açısından ...
Tülay Akbaba
doaj   +1 more source

Longitudinal metabolomics of human plasma reveal metabolic dynamics and predictive markers of antituberculosis drug-induced liver injury

Respiratory Research
Tuberculosis (TB) remains the second leading cause of death from a single infectious agent and long-term medication could lead to antituberculosis drug-induced liver injury (ATB-DILI).
Mengjiao Li, Dan Zhang, Qingxin Yang, Zhenzhen Zhao, Chunying Zhang, Yanbing Zhou, Yangjuan Bai, Lu Chen, Xiaoyan Tang, Cuihua Liu, Juan Zhou, Xuerong Chen, Binwu Ying   +12 more
doaj   +1 more source

Evaluation of glutamate dehydrogenase (GLDH) as a diagnostic and prognostic marker in drug-induced liver injury

Gastroenterology Review
Omkolsoum Alhaddad, Maha Elsabaawy, Amany Salah, Olfat Hendy, Dalia Elsabaawy, Mohamed Mazaly, Aliaa Sabry   +6 more
doaj   +1 more source

A multiparametric in vitro strategy for small molecule drug-induced liver injury risk mitigation in early drug development. [PDF]

Toxicol Sci
Norona LM, Melnikov F, Kiyota T, Lawson C, Khojasteh C, Liu J, Johnson K, Pourmohamad T, Anger LT, Proctor WR, Fullerton AM.   +10 more
europepmc   +1 more source

Risk of drug-induced liver injury in multiple system atrophy patients treated with KM-819 is potentially associated with the HLA-DPB1*05:01:01:01 allele. [PDF]

Pharmacogenomics J
Han JH, Andrade RJ, Björnsson ES, Lewis JH, Lucena MI, Go S, Stankeviciute S, Aithal GP, Kim K, Lee CS, Barlow C, Kim E.   +11 more
europepmc   +1 more source

Hippocampal NLRP3 Inflammasome Drives Anxiety- and Depressive-Like Behaviors Following Drug-Induced Liver Injury. [PDF]

Int J Biol Sci
Zhang H, Zhuang JL, Ma R, Wang S, Huang J, Yang HX, Hu MM, Wei XL, Shen HY, Fang H, Wu WN, Wang H.   +11 more
europepmc   +1 more source

HLA and non-HLA genetic analyses reveal suggestive variants associated with statin-induced liver injury. [PDF]

Hepatol Commun
Zaborenko CJ, Schwantes-An TH, Li YJ, Dellinger A, Nicoletti P, Daly AK, Aithal G, Chalasani N, Drug-Induced Liver Injury Network.   +8 more
europepmc   +1 more source

Application of metabolomics in drug-induced liver injury: A systematic review. [PDF]

J Transl Int Med
Sun X, Li X, Li X, Jin S, Wang N, He M, Zhou L, Zhang W, Xiong X, Zhao L.   +9 more
europepmc   +1 more source