Results 51 to 60 of about 13,535 (197)

Clinical Characteristics of Patients with Drug-induced Liver Injury

Chinese Medical Journal, 2017
Background: Drug is an important cause of liver injury and accounts for up to 40% of instances of fulminant hepatic failure. Drug-induced liver injury (DILI) is increasing while the diagnosis becomes more difficult.
Li-Xia Yang, Cheng-Yuan Liu, Lun-Li Zhang, Ling-Ling Lai, Ming Fang, Chong Zhang   +5 more
doaj   +1 more source

Determinants of Early Renal Function Recovery After TIPS in Patients With Portal Hypertension

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal dysfunction frequently occurs in patients with portal hypertension and is linked to unfavorable clinical outcomes. Transjugular intrahepatic portosystemic shunt (TIPS) has the potential to enhance renal perfusion through portal decompression; however, factors predicting early improvement in renal function remain insufficiently defined ...
Meng Jia, Yang Luo, Zhao‐Yang Tan, Xiao‐Ling Zhou, Xi‐You Zhang, Jing‐Ying Sun, Ye Du   +6 more
wiley   +1 more source

Oral GLP‐1RA TERN‐601 for Adults With Obesity/Overweight: Placebo‐Controlled, Multiple‐Ascending‐Dose, Phase 1 and 2 Studies

Obesity, EarlyView.
ABSTRACT Objective The safety, tolerability, pharmacokinetics, and efficacy of TERN‐601, a once‐daily, oral small‐molecule glucagon‐like peptide‐1 (GLP‐1) receptor agonist, were studied in Phase 1 and 2 clinical studies. Methods The Phase 1 (28‐day) and Phase 2 (12‐week), randomized, double‐blind, placebo‐controlled, multiple‐ascending‐dose studies ...
W. Timothy Garvey, Julio Rosenstock, Harold E. Bays, Douglas Denham, Anita Kohli, Melanie Haines, Christopher Jones, Ellen Kwan, Erin Castelloe, Tonya Marmon, Emil Kuriakose, Cara Nelson   +11 more
wiley   +1 more source

Morphological evolution of colonial space in island cities: a case study in the Dili City, Timor-Leste

Journal of Asian Architecture and Building Engineering
Island cities’ spatial form shapes their unique land-sea integrated development model and profoundly influences urban functional layout, resource utilization, and cultural inheritance, with Dili serving as a typical case of colonial planning-influenced ...
Yile Chen, Qingnian Deng, Jingwei Liang, Yuhao Huang, Liang Zheng, Jiaying Fang   +5 more
doaj   +1 more source

Dili

, 2021
Dissertação de Mestrado em Arquitetura com a especialização em Arquitetura apresentada na Faculdade de Arquitetura da Universidade de Lisboa para obtenção do grau de Mestre.
openaire   +1 more source

Head‐to‐Head Comparison of Four Ultrasound Elastography Techniques in Detecting Advanced Fibrosis

Portal Hypertension &Cirrhosis, EarlyView.
Elastography is an important noninvasive method for diagnosing advanced fibrosis (AF); however, evidence remains insufficient, particularly regarding acoustic radiation force impulse (ARFI) techniques. This prospective mulitcenter study concludes that vibration controlled transient elastography (VCTE) demonstrates superior diagnostic performance to ...
Jiahao Han, Lichen Chu, Lixin Yang, Kexin Lou, Guangbin Dou, Huiming Shen, Xiaojun Cheng, Zuowei Bao, Jia Li   +8 more
wiley   +1 more source

Multi-Stakeholder Engagement in Community-Based Tourism Development: Evidence from Pante Makassar, Timor-Leste

International Journal of Home Economics, Hospitality and Allied Research
This study examined the stakeholders' engagement in Community-Based Tourism (CBT) in Pante Makassar, Oe-Cusse, Timor-Leste. The stakeholders included the local community, the private sector, tourists, and the local government.
Cevat Tosun, Nicolao Salvador Marques, Helio Brites da Silva   +2 more
doaj   +1 more source

From politics to economics: The investigation of the determinants of local administrative hierarchy in the Tang–Song transition

Asia‐Pacific Economic History Review, Volume 65, Issue 1, Page 39-78, March 2025.
Abstract This study collects original data to examine the determinants of classification criteria of county hierarchy and its rank variations during the Tang–Song period. The results reveal that the county hierarchy was affected by both economic and political situations, with more emphasis on politics in Tang and economics in Song.
Nan Li, Heqi Cai
wiley   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean C. Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source