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Rapid health technology assessment of six non-ergot dopamine-receptor agonists for the treatment of early Parkinson's disease. [PDF]
Lv J +6 more
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EPA-lactone derivative, 5,6-diHETE lactone, improves pulmonary arterial hypertension in a monocrotaline-induced model. [PDF]
Dhananjayan K +5 more
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Exploring patient perspectives on the impact of resuming cost sharing: a qualitative analysis. [PDF]
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Formulation of Sustained-Release Verapamil HCl and Diltiazem HCl Semisolid Matrix Capsules
Pharmaceutical Development and Technology, 2008Semisolid matrix capsule formulations of verapamil HCl and diltiazem HCl prepared by hot-melt capsule filling are an especially appealing and simple way to make sustained-release formulations. Semisolid matrices of Gelucire 50/13 and stearic acid combination eroded and disintegrated at various rates, depending on the combination of waxes, and drug ...
Chien N, Nguyen +2 more
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Liposomal diltiazem HCl as ocular drug delivery system for glaucoma
Drug Development and Industrial Pharmacy, 2013In this study, unilamellar liposomal vesicles of diltiazem HCl (DH) were prepared using either reversed phase evaporation (REV) or proliposome methods. Soya phosphatidylcholine (SPC) was used for preparing the liposomes, and the vesicles were rigidified using cholesterol (Chol) or cetyl alcohol (CA) in different molarities.
Mahmoud, Mokhtar Ibrahim +2 more
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Chronotherapy of Cardiac Diseases using Diltiazem HCl-A Review
Research Journal of Pharmacy and Technology, 2015Hypertension is associated with increased cardio and cerebrovascular morbidity and mortality; antihypertensive drugs have been shown to reduce the risk of adverse cardio and cerebrovascular events. These events tend to be more common during the morning hours, a time when both normo and hypertensives show a circadian peak in blood pressure (BP ...
V. Kamalakkannan +3 more
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Validation of manufacturing process of Diltiazem HCl tablets by NIR spectrophotometry (NIRS)
Journal of Pharmaceutical and Biomedical Analysis, 2007The goal of this study was to apply the Process Analytical Technology FDA's initiative in pharmaceutical tablets manufacturing. Near Infrared Spectrophotometry (NIRS) was used as a non-destructive, very fast technique requiring no sample preparation. Direct compression powder blends containing Diltiazem HCl as a model drug were pressed into tablets for
Bodson, Cédric +5 more
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