Advanced Science, Volume 11, Issue 11, March 20, 2024.Chronic pain remains the number one public health crisis in the US and around the world. Phenotypic screening assays for identifying novel analgesics are desperately needed. Here, the authors report on the development and characterization of an inflammatory nociception screening assay based on spontaneous and evoked activity from human induced ...
Bryan James Black +5 more
wiley +1 more source
Removal of pharmaceuticals in WWTP effluents by ozone and hydrogen peroxide [PDF]
, 2014 Ozonation to achieve removal of pharmaceuticals from wastewater effluents, with pH values in the upper and lower regions of the typical range for Swedish wastewater, was investigated.
Andersen, H. R. +7 more
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International Journal of Hypertension, Volume 2024, Issue 1, 2024.The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting the management and administration of drugs, as well as treatment and diagnosis.
Preeti +10 more
wiley +1 more source
Fixed combinations in the management of hypertension: Patient perspectives and rationale for development and utility of the olmesartan – amlodipine combination [PDF]
, 2008 Although the awareness and control of hypertension has increased, only 37% of hypertensive patients in the US achieve the conservative goal ...
Pimenta, Eduardo, Oparil, Suzanne
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Paradigm shift for preparing versatile M2+-free gels from unmodified sodium alginate [PDF]
, 2017 This manuscript describes a new route to prepare rapidly Ca2+-free hydrogels from unmodified sodium alginate by simply mixing with small organic molecules such as poly(carboxylic acid) compounds as cross-linker agents instead of classical divalent metal ...
Alemán Llansó, Carlos +5 more
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Drug-Phospholipid Complex-loaded Matrix Film Formulation for the Enhanced Transdermal Delivery of Quercetin [PDF]
, 2018 A novel quercetin-phospholipid-complex(QPLC)-loaded matrix film for improved transdermal delivery of quercetin was developed. The QPLC formulation, prepared using a solvent-evaporation method, was optimized using a central-composite design. The optimized
Anand, Sridhar +5 more
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Going Natural: Using polymers from nature for gastroresistant applications [PDF]
, 2017 Nutraceuticals provide an additional health or medicinal benefit besides their nutritional value and are therefore marketed for the prevention and treatment of certain conditions.
Barbara Conway +3 more
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One of These Things Is Not Quite the Same: A Comparison of the Patent Doctrine of Equivalents with Suitability for Filing an Abbreviated New Drug Application [PDF]
, 2012 The doctrine of equivalents as applied to chemical patents is compared to the FDA’s findings of bioequivalence in reviewing suitability petitions for filing Abbreviated New Drug Applications (ANDAs).
Halstead, David P.
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Novel salted anionic-cationic polymethacrylate polymer blends for sustained release of acidic and basic drugs [PDF]
, 2017 Background: Since a unique matrix tablet formulation that independently controls the release of various drug types is in a great demand, the objective of this research was to develop a sustained release matrix tablet as a universal dosage form using a ...
Al-Jabery, Ahmad +4 more
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Drug release evaluation of Diltiazem HCl CR preparations [PDF]
Journal of Pharmacy and Pharmacology, 1998 Anurag Sood, Ramesh Panchagnula
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