Advanced Science, Volume 11, Issue 11, March 20, 2024.Chronic pain remains the number one public health crisis in the US and around the world. Phenotypic screening assays for identifying novel analgesics are desperately needed. Here, the authors report on the development and characterization of an inflammatory nociception screening assay based on spontaneous and evoked activity from human induced ...
Bryan James Black +5 more
wiley +1 more source
International Journal of Hypertension, Volume 2024, Issue 1, 2024.The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting the management and administration of drugs, as well as treatment and diagnosis.
Preeti +10 more
wiley +1 more source
Paradigm shift for preparing versatile M2+-free gels from unmodified sodium alginate [PDF]
, 2017 This manuscript describes a new route to prepare rapidly Ca2+-free hydrogels from unmodified sodium alginate by simply mixing with small organic molecules such as poly(carboxylic acid) compounds as cross-linker agents instead of classical divalent metal ...
Alemán Llansó, Carlos +5 more
core +2 more sources
Going Natural: Using polymers from nature for gastroresistant applications [PDF]
, 2017 Nutraceuticals provide an additional health or medicinal benefit besides their nutritional value and are therefore marketed for the prevention and treatment of certain conditions.
Barbara Conway +3 more
core +1 more source
Guru pembelajar modul paket keahlian farmasi SMK kelompok kompetensi H: teknik sediaan tablet, steril dan pelayanan farmasi, penilaian pembelajaran [PDF]
, 2016 Modul Guru Pembelajar Mata Pelajaran Farmasi SMK ini terdiri atas 2 materi pokok, yaitu: materi profesional dan materi pedagogik. Masing-masing materi dilengkapi dengan tujuan, indikator pencapaian kompetensi, uraian materi, aktivitas pembelajaran ...
Hartati, Hartati, Nila, Aster
core
Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study [PDF]
, 2017 Overexpression of the efflux pump P-glycoprotein (P-gp) is one of the important mechanisms of multidrug resistance (MDR) in many tumor cells. In this study, 26 novel 5-oxo-hexahydroquinoline derivatives containing different nitrophenyl moieties at C-4 ...
Edraki, N. +7 more
core +1 more source
Novel salted anionic-cationic polymethacrylate polymer blends for sustained release of acidic and basic drugs [PDF]
, 2017 Background: Since a unique matrix tablet formulation that independently controls the release of various drug types is in a great demand, the objective of this research was to develop a sustained release matrix tablet as a universal dosage form using a ...
Al-Jabery, Ahmad +4 more
core +1 more source
One of These Things Is Not Quite the Same: A Comparison of the Patent Doctrine of Equivalents with Suitability for Filing an Abbreviated New Drug Application [PDF]
, 2012 The doctrine of equivalents as applied to chemical patents is compared to the FDA’s findings of bioequivalence in reviewing suitability petitions for filing Abbreviated New Drug Applications (ANDAs).
Halstead, David P.
core
Drug release evaluation of Diltiazem HCl CR preparations [PDF]
Journal of Pharmacy and Pharmacology, 1998 Anurag Sood, Ramesh Panchagnula
openaire +1 more source
Drug-Phospholipid Complex-loaded Matrix Film Formulation for the Enhanced Transdermal Delivery of Quercetin [PDF]
, 2018 A novel quercetin-phospholipid-complex(QPLC)-loaded matrix film for improved transdermal delivery of quercetin was developed. The QPLC formulation, prepared using a solvent-evaporation method, was optimized using a central-composite design. The optimized
Anand, Sridhar +5 more
core +1 more source