Results 41 to 50 of about 5,257 (204)

In situ monitoring of powder blending by non-invasive Raman spectrometry with wide area illumination [PDF]

open access: yes, 2013
A 785 nm diode laser and probe with a 6 mm spot size were used to obtain spectra of stationary powders and powders mixing at 50 rpm in a high shear convective blender.
Allan, Pamela   +5 more
core   +1 more source

Case Report: Oxaliplatin-Induced Third-Degree Atrioventricular Block: First Discovery of an Important Side-Effect

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundThe adverse effects of anticancer therapy in patients with malignancies and cardiovascular diseases are complicated. Oxaliplatin is one of the most commonly used chemotherapy drugs for gastric and colorectal cancers, and oxaliplatin-induced ...
Xi Chen   +6 more
doaj   +1 more source

Niacin-induced clotting factor synthesis deficiency with coagulopathy [PDF]

open access: yes, 1992
Although coagulopathy is a well-known complication of severe niacin- induced hepatotoxic reaction, it is not found in patients with minimal aminotransferase level elevations.
Dearing, Brian D.   +3 more
core   +1 more source

Heart Failure: Epidemiology, Pathophysiology, and Management

open access: yesMedComm, Volume 7, Issue 3, March 2026.
This article takes calcium homeostasis as the point of departure to provide an overview of heart failure from three perspectives—epidemiology, pathophysiological mechanisms, and management strategies—and summarizes the current unmet needs and future directions in the field. ABSTRACT Heart failure (HF) is one of the leading causes of hospitalization and
Yujian Fan   +9 more
wiley   +1 more source

Increase in systolic blood pressure during exercise testing after heart transplantation: correlation with the clinical condition and ventricular function assessed by dobutamine stress echocardiography [PDF]

open access: yes, 2006
OBJECTIVE: Patients who underwent heart transplantation (HTX) experience a reduction in the elevation that is usual in systolic blood pressure during exercise testing. Of unknown origin, this phenomenon varies in frequency and intensity.
Almeida, Dirceu Rodrigues de   +7 more
core   +4 more sources

Anogenital Contact Dermatitis in Spain: A REIDAC Study of Patients Undergoing Patch Testing in 2019–2024

open access: yesContact Dermatitis, Volume 94, Issue 3, Page 272-285, March 2026.
Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez   +29 more
wiley   +1 more source

Development and validation of a stability indicating HPLC method to determine diltiazem hydrochloride in tablets and compounded capsules

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2017
A stability indicating HPLC method to determine diltiazem hydrochloride (DTZ) in tablets and compounded capsules was developed and validated according to Brazilian and the International Conference on Harmonization (ICH) guidelines.
Mateus Araújo Castro e Souza   +3 more
doaj   +1 more source

Improved crystal structure solution from powder diffraction data by the use of conformational information [PDF]

open access: yes, 2017
The effect of introducing conformational information to the DASH implementation of crystal structure determination from powder diffraction data is investigated using 51 crystal structures, with the aim of allowing increasingly complex crystal structures ...
Adrian C. Williams   +56 more
core   +1 more source

A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands

open access: yesChemMedChem, Volume 21, Issue 4, 25 February 2026.
A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova   +15 more
wiley   +1 more source

Aortic Stiffness in L-NAME Treated C57Bl/6 Mice Displays a Shift From Early Endothelial Dysfunction to Late-Term Vascular Smooth Muscle Cell Dysfunction

open access: yesFrontiers in Physiology, 2022
Introduction and Aims: Endothelial dysfunction is recognized as a cardiovascular aging hallmark. Administration of nitric oxide synthase blocker N-Ω-Nitro-L-arginine methyl ester hydrochloride (L-NAME) constitutes a well-known small animal model of ...
Sofie De Moudt   +7 more
doaj   +1 more source

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