Results 31 to 40 of about 246,439 (294)
Inhibition of methionine sulfoxide reduction by dimethyl sulfoxide
BMB Reports, 2009 Dimethyl sulfoxide (DMSO) is widely used in chemistry and biology as a solvent and as a cryoprotectant. It is also used as a pharmaceutical agent for the treatment of interstitial cystitis and rheumatoid arthritis. Previous reports described DMSO as being reduced by methionine-S-sulfoxide reductase (MsrA).
Kim +3 more
openaire +4 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Acta Crystallographica Section E, 2008 The title compound, [Cu2(C18H19N3O2)2]·2C2H6OS or [Cu2(SalenN3H)2]·2DMSO, where SalenN3H is the multidentate Schiff base 2,2′-[(3-azapentane-1,5-diyl)bis(nitrilomethylidyne)]diphenolate dianion and DMSO is dimethyl sulfoxide, is a ...
Yasmi Reyes-Ortega +4 more
doaj +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Diaqua[(E)-2-(2-oxidobenzylideneamino)-2-phenylacetato]zinc(II) dimethyl sulfoxide monosolvate
Acta Crystallographica Section E, 2009 In the title compound, [Zn(C15H11NO3)(H2O)2]·C2H6OS, the Zn(II) ion is coordinated by two O atoms and one N atom of the deprotonated chelate ligand and two water molecules in a distorted trigonal bipyramidal coordination environment.
Jun You +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
1,5-Bis[(E)-1-(2-hydroxyphenyl)ethylidene]carbonohydrazide dimethyl sulfoxide solvate
Acta Crystallographica Section E, 2009 The title dimethyl sulfoxide (DMSO) solvate, C17H18N4O3·C2H6OS, shows the disubstituted urea derivative to adopt an almost planar geometry (r.m.s.
Julio Zukerman-Schpector +3 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
3-[2-(9H-Carbazol-9-yl)ethyl]-4-phenyl-1H-1,2,4-triazole-5(4H)-thione dimethyl sulfoxide monosolvate
IUCrData, 2016 In the title compound, C22H18N4S·C2H6OS, the central triazolethione ring is inclined to the carbazole ring system by 13.97 (18)° and to the phenyl ring by 66.4 (1)°.
Shaaban K. Mohamed +4 more
doaj +1 more source
IUCrData, 2022 In the structure of the title solvated complex, [Pt(C8H4N2S2)2(C5H6N2)2]·C2H6OS or trans-[Pt(4-ap)2(qdt)2]·dmso (4-ap = 4-aminopyridyl, C5H6N2; qdt = quinoxaline-2,3-dithiolate, C8H4N2S2; dmso = dimethyl sulfoxide, C2H6OS) the centrosymmetric complex ...
Jiandu Hu +2 more
doaj +1 more source