Results 31 to 40 of about 386,611 (320)

2-(5-Bromo-1H-indol-3-yl)-4-(4-bromophenyl)-5-(4-chlorobenzoyl)-1H-pyrrole-3-carbonitrile dimethyl sulfoxide monosolvate

IUCrData, 2016
In the title solvated compound, C26H14Br2ClN3O·C2H6OS, the indole ring is inclined to the central pyrrole ring by 25.7 (2)°. The chlorobenzene ring and the bromobenzene rings subtend dihedral angles of 56.5 (2) and 53.4 (2)°, respectively, with the ...
Y. AaminaNaaz, Jayabal Kamalraja, G. Vimala, Paramasivam T. Perumal, A. SubbiahPandi   +4 more
doaj   +1 more source

3-[1-(3-Hydroxybenzyl)-1H-benzimidazol-2-yl]phenol dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2012
Crystals of the title compound were obtained as a 1:1 dimethyl sulfoxide solvate, C20H16N2O2·C2H6O. The molecular conformation of the organic molecule is similar to that in the previously reported unsolvated structure [Eltayeb et al.
Magdalena Quezada-Miriel, Alcives Avila-Sorrosa, Juan Manuel German-Acacio, Reyna Reyes-Martínez, David Morales-Morales   +4 more
doaj   +1 more source

Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia [PDF]

, 2012
This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfluidic approach.
Brognara, Eleonora, Capretto, Lorenzo, Carugo, Dario, Gambari, Roberto, Hill, Martyn, Lampronti, Ilaria, Mazzitelli, Stefania, Nastruzzi, Claudio, Zhang, Xunli   +8 more
core   +2 more sources

(E)-6-Bromo-3-{2-[2-(2-chlorobenzylidene)hydrazinyl]thiazol-5-yl}-2H-chromen-2-one dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2011
In the title compound C19H11N3O2SClBr·C2H6OS, the molecule adopts an E configuration about the central C=N double bond. The chromene ring system and the thiazole ring are approximately planar, with maximum deviations of 0.027 (2) and 0.
Afsheen Arshad, Hasnah Osman, Chan Kit Lam, Madhukar Hemamalini, Hoong-Kun Fun   +4 more
doaj   +1 more source

4-Amino-3-[2-(9H-carbazol-9-yl)ethyl]-1H-1,2,4-triazole-5(4H)-thione dimethyl sulfoxide monosolvate

IUCrData, 2016
In the crystal of the title compound, C16H15N5S·C2H6OS, both the 1,2,4-triazole derivative molecules and the disordered [refined occupancy ratio = 0.604 (1):0.396 (1)] dimethyl sulfoxide solvent molecules form centrosymmetric dimers, by way of pairwise N—
Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Talaat I. El-Emary, Mustafa R. Albayati   +4 more
doaj   +1 more source

A kinetic and theoretical study of the borate catalysed reactions of hydrogen peroxide: the role of dioxaborirane as the catalytic intermediate for a wide range of substrates [PDF]

, 2012
Our recent work has provided new insights into the equilibria and species that exist in aqueous solution at different pHs for the boric acid – hydrogen peroxide system, and the role of these species in oxidation reactions. Most recently, (M. C.
Abel, Adam, Amels, Bennett, Bunton, Chernyshov, Curci, Curci, Curci, D. Martin Davies, Davies, Davies, Davies, Duffin, Durrant, Fortnum, Hansch, Hanson, Hanson, Hoffmann, Hoffmann, Hussain, Ingri, Kamyshny, Lin, Lin, Marcus C. Durrant, Marenich, Maya, Mckillop, McKillop, Michael E. Deary, Mohammad, Muzart, Ogata, Pizer, Salentine, Sawaki, Sawwan, Schubert, Spessard, Wilson, Wilson, Wilson   +43 more
core   +1 more source

Di-μ-oxido-bis({2-[(R,R)-(−)-(2-aminocyclohexyl)iminomethyl]-4-nitrophenolato-κ3N,N′,O}oxidovanadium(V)) dimethyl sulfoxide disolvate

Acta Crystallographica Section E, 2009
The title compound, [V2(C13H16N3O3)2O4]·2C2H6OS, is a centrosymmetric dimeric complex solvated by two dimethyl sulfoxide molecules. Each VV atom is six-coordinated by one oxide group, two N atoms and one O atom from the tridentate Schiff base ligand,
Grzegorz Romanowski, Michał Wera, Artur Sikorski   +2 more
doaj   +1 more source

JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand. [PDF]

, 2009
Background: cJun terminal kinase (JNK) is constitutively activated in most hepatocellular carcinomas (HCCs), yet its exact role in carcinogenesis remains controversial.
Bruns, Christiane, Camaj, Peter, De Toni, Enrico, Eichhorst, Sören T., Gallmeier, Eike, Gerbes, Alexander L., Göke, Burkhard, Kolligs, Frank T., Mucha, Simon R., Rizzani, Antonia, Thasler, Wolfgang E.   +10 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The influence of reaction conditions on the Diels-Alder cycloadditions of 2-thio-3-chloroacrylamides; investigation of thermal, catalytic and microwave conditions [PDF]

, 2010
The Diels-Alder cycloadditions of cyclopentadiene and 2,3-dimethyl-1,3-butadiene to a range of 2-thio-3-chloroacrylamides under thermal, catalytic and microwave conditions is described.
Chopra, Jay, Kissane, Marie, Lawrence, Simon E., Lynch, Denis, Maguire, Anita R.   +4 more
core   +1 more source