Results 141 to 150 of about 2,282 (176)
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[Biotransformation of dimethylnitrosamine].
Journal de toxicologie clinique et experimentale, 1991NDMA, one of the most widely occurring carcinogenic compounds in the environment, is present in human food (meat, vegetables, cheese and alcohol beverages), in drinking water, in drugs, in cosmetics, in tobacco and its smokes. Furthermore NDMA may be synthesized from nitrates and nitrites and endogen or exogen amines.
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The influence of DDT on metabolism of dimethylnitrosamine in rats
Toxicology and Applied Pharmacology, 1978The rate of in vitro metabolism of dimethylnitrosamine (DMNA) in liver cell preparations from rats given ip injections of DDT (50 mg/kg every second day for two, four, or eight doses) or a single ip injection of 3-methylcholanthrene (100 mg/kg) was compared with the rate of preparations obtained from control rats. The activity of O-demethylase in liver
T, Syrowatka, B, Wiadrowska
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Dimethylnitrosamine adducts excreted in rat urine
Chemico-Biological Interactions, 1982Rats were injected with [14C]dimethylnitrosamine and urine was collected up to 5 days after the injection. Urine samples were concentrated and subjected to Sephadex G-10 chromatography. Three peaks of radioactivity (I-III, in the order of elution) were observed for all injection times.
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Effects of dimethylnitrosamine on some actions of testosterone
Toxicology Letters, 1981Using homogenates of mouse kidney and testes, the activities of the enzymes, beta-glucuronidase and beta-galactosidase, were studied as markers of androgen action. The results obtained differed between testes and kidney homogenates. Dimethylnitrosamine (DMN) may cause a competitive inhibition of the anabolic action of testosterone in kidney homogenates
F I, Ikegwuonu, T A, Aire, S O, Ogwuegbu
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PHOTOINDUCED REACTION OF DIMETHYLNITROSAMINE WITH DNA AND POLYNUCLEOTIDES
Photochemistry and Photobiology, 1981Abstract— The interaction between products from dimethylnitrosamine photolytic breakdown and DNA is time‐dependent and the reaction with polyguanylic acid is 36 times higher than that occurring with other polyribonucleotides; such interactions occur only if nucleic acids are present during dimethylnitrosamine photolytic breakdown.
G, Arfellini +3 more
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The evidence for the presence of dimethylnitrosamine in meat products
Food and Cosmetics Toxicology, 1972Summary Trace amounts (approximately 0·01–0·08 ppm) of dimethylnitrosamine were detected in five samples of prepared meat products out of 59 investigated. The identity of the isolated nitrosamine was confirmed by gas—liquid chromatographic (GLC) analysis of the oxidation product (dimethylnitramine) and also by GLC—mass spectrometric analysis of the ...
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Dimethylnitrosamine levels in untreated herring meals
Journal of the Science of Food and Agriculture, 1976AbstractAn investigation has been conducted to determine the levels of dimethylnitrosamine in 13 samples of Canadian herring meals taken from the Atlantic and Pacific coasts. The concentration of dimethylnitrosamine found in these meals, which had not been treated with nitrate or nitrite varied between 0.15 and 1.0 parts/106.
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Toxicity of dimethylnitrosamine for the rat testis
The Journal of Pathology, 1970G C, Hard, W H, Butler
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The hepatotoxic effects of dimethylnitrosamine in the rat
The Journal of Pathology and Bacteriology, 1966S D, Khanna, D, Puri
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