Results 11 to 20 of about 2,930 (198)

Transient destabilization of whole brain dynamics induced by N,N-Dimethyltryptamine (DMT) [PDF]

Communications Biology
The transition towards the brain state induced by psychedelic drugs is frequently neglected in favor of a static description of their acute effects. We use a time-dependent whole-brain model to reproduce large-scale brain dynamics measured with fMRI from
Juan Ignacio Piccinini, Yonatan Sanz Perl, Carla Pallavicini, Gustavo Deco, Morten Kringelbach, David Nutt, Robin Carhart-Harris, Christopher Timmermann, Enzo Tagliazucchi   +8 more
doaj   +2 more sources

Best practices for first psychedelic experiences: harm reduction advice from the psychedelic community [PDF]

Harm Reduction Journal
Background The use of psychedelics is currently increasing in the United States. Awareness of clinical trials investigating the therapeutic applications of psychedelics may result in a record number of people who use psychedelics for the first-time. This
Daniel J. Kruger, Gina Mersereau, Ashley Sullivan, Julie Barron, Moss Herberholz, Niloufar Pouyan, Jacob S. Aday, Kevin F. Boehnke   +7 more
doaj   +2 more sources

The excretion of dimethyltryptamine in psychiatric patients. [PDF]

Proceedings of the Royal Society of Medicine, 1976
Robin Murray, M.C.H. Oon
  +6 more sources

Acute Intoxication following Dimethyltryptamine Ingestion [PDF]

Case Reports in Emergency Medicine, 2018
Ayahuasca is a hallucinogenic tea that is most commonly comprised of the vine Banisteriopsis caapi alone or in combination with other plants such as Psychotria viridis. This concoction results in an orally active form of dimethyltryptamine (DMT), a hallucinogenic amine.
Matthew H. Bilhimer, Rachel F. Schult, Kristan V. Higgs, Timothy J. Wiegand, Rachel M. Gorodetsky, Nicole M. Acquisto   +5 more
openaire   +3 more sources

Global Increases in Brain Glucose Metabolism Following Acute N,N-Dimethyltryptamine and Harmine Administration in Healthy Volunteers: An [¹⁸F]FDG-PET Study [PDF]

Egger K, Bozsak R, Aicher H, Sari H, Poetzsch S, Rominger A, Martin-Soelch C, Dornbierer D, Quednow B, Scheidegger M, Cumming P.   +10 more
europepmc   +2 more sources

Effects of Ayahuasca on Personality: Results of Two Randomized, Placebo-Controlled Trials in Healthy Volunteers

Frontiers in Psychiatry, 2021
Rationale: Previous studies with the serotonergic hallucinogens LSD and psilocybin showed that these drugs induced changes in personality traits, such as increases in Openness.
Juliana Mendes Rocha, Giordano Novak Rossi, Flávia L. Osório, Flávia L. Osório, José Carlos Bouso Saiz, José Carlos Bouso Saiz, José Carlos Bouso Saiz, Gabriela De Oliveira Silveira, Mauricio Yonamine, Eduardo José Crevelin, Maria Eugênia Queiroz, Maria Eugênia Queiroz, Maria Eugênia Queiroz, Jaime E. Cecílio Hallak, Jaime E. Cecílio Hallak, Rafael Guimarães Dos Santos, Rafael Guimarães Dos Santos, Rafael Guimarães Dos Santos   +17 more
doaj   +1 more source

An Encounter With the Other: A Thematic and Content Analysis of DMT Experiences From a Naturalistic Field Study

Frontiers in Psychology, 2021
Introduction:N,N-dimethyltryptamine (DMT) is an endogenous serotonergic psychedelic capable of producing radical shifts in conscious experience. Increasing trends in its use, as well as new trials administering DMT to patients, indicate the growing ...
Pascal Michael, David Luke, David Luke, Oliver Robinson   +3 more
doaj   +1 more source

Infoveillance and Critical Analysis of the Systematically Reviewed Literature on Dimethyltryptamine and the “God Molecule”

Pharmaceuticals, 2023
Aboriginals of Latin America have used DMT (N,N-dimethyltryptamine) in ritualistic ceremonies for centuries. Nevertheless, there are limited data on web users’ interest concerning DMT.
Ahmed Al-Imam, Marek A. Motyka, Beata Hoffmann, Anita Magowska, Michal Michalak   +4 more
doaj   +1 more source

In Vitro Study of the Bioavailability and Bioaccessibility of the Main Compounds Present in Ayahuasca Beverages

Molecules, 2021
Ayahuasca is a psychoactive beverage that contains the psychoactive compound N,N-dimethyltryptamine and β-carboline alkaloids. This study aims at determining in vitro the bioavailability and bioaccessibility of the main compounds present in decoctions of
Joana Gonçalves, Miguel Castilho, Tiago Rosado, Ângelo Luís, José Restolho, Nicolás Fernández, Eugenia Gallardo, Ana Paula Duarte   +7 more
doaj   +1 more source

Novel Psychoactive Substances—Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs

Frontiers in Psychiatry, 2017
A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Zurina Hassan, Oliver G. Bosch, Darshan Singh, Suresh Narayanan, B. Vicknasingam Kasinather, Erich Seifritz, Johannes Kornhuber, Boris B. Quednow, Christian P. Müller   +8 more
doaj   +1 more source