Results 1 to 10 of about 3,892 (211)
Pharmaceuticals, 2023 Aboriginals of Latin America have used DMT (N,N-dimethyltryptamine) in ritualistic ceremonies for centuries. Nevertheless, there are limited data on web users’ interest concerning DMT.
Ahmed Al-Imam +4 more
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Dimethyltryptamine: Endogenous Role and Therapeutic Potential [PDF]
Journal of Psychoactive Drugs, 2019 N, N-dimethyltryptamine (DMT) is an indole alkaloid produced by a number of plants and animals, including humans. Its psychoactive effects were first described in 1956 by Stephen Szára, but have been exploited for centuries by South American indigenous populations in the form of ayahuasca. In the present review, we assess the state of the art regarding
Alexandra Vsl, Rodrigues +2 more
exaly +3 more sources
Structural Pharmacology of Bufotenine Derivatives in Activating the 5-HT1A Receptor for Therapeutic Potential in Depression and Anxiety [PDF]
ResearchThe 5-HT1A receptor is a critical target in the treatment of depression and anxiety. Bufotenine derivatives, such as 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), 5-hydroxy-N,N-dimethyltryptamine (5-OH-DMT), and 5-hydroxy-N,N,N-dimethyltryptamine—derived
Shu-jie Li +16 more
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Computational evaluation of aluminum and zinc doped C20 fullerenes as advanced sensors for the detection of the narcotic dimethyltryptamine [PDF]
Scientific ReportsN, N-Dimethyltryptamine (N, N-DMT) is a potent psychedelic substance whose detection is crucial in medical and forensic contexts. In this study, we computationally evaluate the potential of aluminum- and zinc-doped C20 fullerenes (AlC19 and ZnC19) as ...
Saad M. Alshahrani
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In silico insights into the adsorption and detection of dimethyltryptamine on metal doped C20 fullerene [PDF]
Scientific ReportsGiven the psychoactive effects of dimethyltryptamine (DMT), classified as a Schedule I drug, developing diagnostic methods is essential. In this computational study, we investigate the adsorption and sensing behavior of DMT on pristine C20 fullerene and ...
Abdulrahman Sumayli +2 more
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Ayahuasca and Its Main Component N,N-Dimethyltryptamine (DMT) for the Treatment of Mental Disorders: Mechanisms of Action, Clinical Studies, and Tools to Explore the Human Mind [PDF]
BiomedicinesIn recent years, psychopharmacology has experienced a significant challenge, highlighting a renewed and strong scientific interest in psychedelics as breakthrough therapies for mental disorders.
Alice Melani +9 more
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Frontiers in Psychiatry, 2021 Rationale: Previous studies with the serotonergic hallucinogens LSD and psilocybin showed that these drugs induced changes in personality traits, such as increases in Openness.
Juliana Mendes Rocha +17 more
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Frontiers in Psychology, 2021 Introduction:N,N-dimethyltryptamine (DMT) is an endogenous serotonergic psychedelic capable of producing radical shifts in conscious experience. Increasing trends in its use, as well as new trials administering DMT to patients, indicate the growing ...
Pascal Michael +3 more
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Neuropharmacology of N,N-dimethyltryptamine [PDF]
Brain Research Bulletin, 2016 N,N-dimethyltryptamine (DMT) is an indole alkaloid widely found in plants and animals. It is best known for producing brief and intense psychedelic effects when ingested. Increasing evidence suggests that endogenous DMT plays important roles for a number of processes in the periphery and central nervous system, and may act as a neurotransmitter.
Theresa M, Carbonaro, Michael B, Gatch
openaire +2 more sources
Molecules, 2021 Ayahuasca is a psychoactive beverage that contains the psychoactive compound N,N-dimethyltryptamine and β-carboline alkaloids. This study aims at determining in vitro the bioavailability and bioaccessibility of the main compounds present in decoctions of
Joana Gonçalves +7 more
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