Results 11 to 20 of about 5,561 (207)

Inhaled N, N-dimethyltryptamine diminishes connectivity between the ventral tegmental area and the nucleus accumbens: relevance to pathologies of mesolimbic and mesocortical pathways [PDF]

Scientific Reports
Reward processing is a broad psychological construct that can be parsed into distinct components known as “reinforcement learning” (learning), “reward responsiveness” (liking), and “motivation to obtain a reward” (wanting).
Gisela Lima, Carla Soares, Marta Teixeira, Marta Pais, Célia Cabral, Patrícia Rijo, Miguel Castelo-Branco   +6 more
doaj   +2 more sources

Transient destabilization of whole brain dynamics induced by N,N-Dimethyltryptamine (DMT) [PDF]

Communications Biology
The transition towards the brain state induced by psychedelic drugs is frequently neglected in favor of a static description of their acute effects. We use a time-dependent whole-brain model to reproduce large-scale brain dynamics measured with fMRI from
Juan Ignacio Piccinini, Yonatan Sanz Perl, Carla Pallavicini, Gustavo Deco, Morten Kringelbach, David Nutt, Robin Carhart-Harris, Christopher Timmermann, Enzo Tagliazucchi   +8 more
doaj   +2 more sources

Dimethyltryptamine (DMT): a biochemical Swiss Army knife in neuroinflammation and neuroprotection? [PDF]

Neural Regeneration Research, 2016
Attila Szabo, Ede Frecska
doaj   +5 more sources

Acute Intoxication following Dimethyltryptamine Ingestion [PDF]

Case Reports in Emergency Medicine, 2018
Ayahuasca is a hallucinogenic tea that is most commonly comprised of the vine Banisteriopsis caapi alone or in combination with other plants such as Psychotria viridis. This concoction results in an orally active form of dimethyltryptamine (DMT), a hallucinogenic amine.
Matthew H. Bilhimer, Rachel F. Schult, Kristan V. Higgs, Timothy J. Wiegand, Rachel M. Gorodetsky, Nicole M. Acquisto   +5 more
openaire   +3 more sources

Effects of Ayahuasca on Personality: Results of Two Randomized, Placebo-Controlled Trials in Healthy Volunteers

Frontiers in Psychiatry, 2021
Rationale: Previous studies with the serotonergic hallucinogens LSD and psilocybin showed that these drugs induced changes in personality traits, such as increases in Openness.
Juliana Mendes Rocha, Giordano Novak Rossi, Flávia L. Osório, Flávia L. Osório, José Carlos Bouso Saiz, José Carlos Bouso Saiz, José Carlos Bouso Saiz, Gabriela De Oliveira Silveira, Mauricio Yonamine, Eduardo José Crevelin, Maria Eugênia Queiroz, Maria Eugênia Queiroz, Maria Eugênia Queiroz, Jaime E. Cecílio Hallak, Jaime E. Cecílio Hallak, Rafael Guimarães Dos Santos, Rafael Guimarães Dos Santos, Rafael Guimarães Dos Santos   +17 more
doaj   +1 more source

An Encounter With the Other: A Thematic and Content Analysis of DMT Experiences From a Naturalistic Field Study

Frontiers in Psychology, 2021
Introduction:N,N-dimethyltryptamine (DMT) is an endogenous serotonergic psychedelic capable of producing radical shifts in conscious experience. Increasing trends in its use, as well as new trials administering DMT to patients, indicate the growing ...
Pascal Michael, David Luke, David Luke, Oliver Robinson   +3 more
doaj   +1 more source

Infoveillance and Critical Analysis of the Systematically Reviewed Literature on Dimethyltryptamine and the “God Molecule”

Pharmaceuticals, 2023
Aboriginals of Latin America have used DMT (N,N-dimethyltryptamine) in ritualistic ceremonies for centuries. Nevertheless, there are limited data on web users’ interest concerning DMT.
Ahmed Al-Imam, Marek A. Motyka, Beata Hoffmann, Anita Magowska, Michal Michalak   +4 more
doaj   +1 more source

In Vitro Study of the Bioavailability and Bioaccessibility of the Main Compounds Present in Ayahuasca Beverages

Molecules, 2021
Ayahuasca is a psychoactive beverage that contains the psychoactive compound N,N-dimethyltryptamine and β-carboline alkaloids. This study aims at determining in vitro the bioavailability and bioaccessibility of the main compounds present in decoctions of
Joana Gonçalves, Miguel Castilho, Tiago Rosado, Ângelo Luís, José Restolho, Nicolás Fernández, Eugenia Gallardo, Ana Paula Duarte   +7 more
doaj   +1 more source

N,N‐dimethyltryptamine and Amazonian ayahuasca plant medicine [PDF]

Human Psychopharmacology: Clinical and Experimental, 2022
AbstractObjectiveReports have indicated possible uses of ayahuasca for the treatment of conditions including depression, addictions, post‐traumatic stress disorder, anxiety and specific psychoneuroendocrine immune system pathologies. The article assesses potential ayahuasca and N,N‐dimethyltryptamine (DMT) integration with contemporary healthcare.
Edward James, Joachim Keppler, Thomas L Robertshaw, Ben Sessa   +3 more
openaire   +3 more sources

A Model for the Application of Target-Controlled Intravenous Infusion for a Prolonged Immersive DMT Psychedelic Experience

Frontiers in Pharmacology, 2016
The state of consciousness induced by N,N-dimethyltryptamine (DMT) is one of the most extraordinary of any naturally-occurring psychedelic substance.
Andrew Robert Gallimore, Rick Strassman
doaj   +1 more source