Acute Intoxication following Dimethyltryptamine Ingestion [PDF]
Ayahuasca is a hallucinogenic tea that is most commonly comprised of the vine Banisteriopsis caapi alone or in combination with other plants such as Psychotria viridis. This concoction results in an orally active form of dimethyltryptamine (DMT), a hallucinogenic amine.
Matthew H. Bilhimer +5 more
core +5 more sources
N,N‐dimethyltryptamine and Amazonian ayahuasca plant medicine [PDF]
AbstractObjectiveReports have indicated possible uses of ayahuasca for the treatment of conditions including depression, addictions, post‐traumatic stress disorder, anxiety and specific psychoneuroendocrine immune system pathologies. The article assesses potential ayahuasca and N,N‐dimethyltryptamine (DMT) integration with contemporary healthcare.
Edward James +3 more
openaire +5 more sources
Psychedelic N,N-dimethyltryptamine and 5-methoxy-N,N-dimethyltryptamine modulate innate and adaptive inflammatory responses through the sigma-1 receptor of human monocyte-derived dendritic cells. [PDF]
The orphan receptor sigma-1 (sigmar-1) is a transmembrane chaperone protein expressed in both the central nervous system and in immune cells. It has been shown to regulate neuronal differentiation and cell survival, and mediates anti-inflammatory ...
Attila Szabo +3 more
doaj +2 more sources
Dimethyltryptamine: hallucinogenic alkaloid on the Central Nervous System [PDF]
Hallucinogenic plants are widely used in rituals and religious cults. Ayahuasca tea and wine black Jurema, both hallucinogenic beverages, present the alkaloid dimethyltryptamine (DMT) responsible for the hallucinogenic effect due to interaction with ...
Darliane Freire Almeida +2 more
doaj +2 more sources
A mystery that has been going on for centuries. The N,N-dimethyltryptamine (DMT) molecule, which is found in every living thing, especially in humans at the time of birth and death, and which some claim to open the door of the parallel universes, is a very harmful hallucinogen for some.
YÜCEL, Kamile
core +3 more sources
Despite many different kinds of substances available for depression treatment, depression itself still appears to be a clinical challenge. Recently, formerly illicit substances came to scientists’ attention, including lysergic acid diethylamide (LSD ...
Gniewko Więckiewicz +4 more
doaj +2 more sources
Transient destabilization of whole brain dynamics induced by N,N-Dimethyltryptamine (DMT) [PDF]
The transition towards the brain state induced by psychedelic drugs is frequently neglected in favor of a static description of their acute effects. We use a time-dependent whole-brain model to reproduce large-scale brain dynamics measured with fMRI from
Juan Ignacio Piccinini +8 more
doaj +2 more sources
Registered Clinical Trials of Ayahuasca and DMT: A Scoping Review. [PDF]
Interest in ayahuasca and its main component, N,N‐Dimethyltryptamine (DMT), has currently moved from historical and experimental use into modern clinical development. Yet, current evidence is fragmented, and systematic mapping of trial methods and design choices remains limited.
Stojanović T +4 more
europepmc +2 more sources
Efficacy of N, N-dimethyltryptamine (DMT) psychedelic therapy for substance misuse: A systematic review and meta-analysis. [PDF]
BACKGROUND: Conventional psychological and pharmacological substance abuse treatments are limited to moderate effect sizes and fail to magnify outcomes when combined.
Wallace LM +5 more
europepmc +2 more sources
Who smokes dimethyltryptamine (DMT)? Characteristics of recreational DMT use
This project is a examination of characteristics of individuals who smoke recreational dimethyltryptamine (DMT)
Mitchell Earleywine, Jamie Parnes
core +1 more source

