Results 21 to 30 of about 5,561 (207)

Recreational use, analysis and toxicity of tryptamines [PDF]

open access: yes, 2015
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio   +3 more
core   +1 more source

Inhibition of alpha oscillations through serotonin-2A receptor activation underlies the visual effects of ayahuasca in humans [PDF]

open access: yes, 2016
Ayahuasca is an Amazonian psychotropic plant tea typically obtained from two plants, Banisteriopsis caapi and Psychotria viridis. It contains the psychedelic 5-HT2A and sigma-1 agonist N,N-dimethyltryptamine (DMT) plus ß-carboline alkaloids with ...
Alonso, Joan Francesc   +12 more
core   +3 more sources

Psychedelics Promote Structural and Functional Neural Plasticity. [PDF]

open access: yes, 2018
Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the fast ...
Barragan, Eden V   +15 more
core   +2 more sources

Herbal highs: review on psychoactive effects and neuropharmacology [PDF]

open access: yes, 2017
Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S   +5 more
core   +1 more source

Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report

open access: yesBrazilian Journal of Psychiatry, 2015
Objectives: Ayahuasca (AYA), a natural psychedelic brew prepared from Amazonian plants and rich in dimethyltryptamine (DMT) and harmine, causes effects of subjective well-being and may therefore have antidepressant actions.
Flávia de L. Osório   +9 more
doaj   +1 more source

Psychedelics: A new era of treatment?

open access: yesEuropean Psychiatry, 2021
Introduction Psychedelics - including LSD (lysergic acid diethylamide), psilocybin, DMT (N, N-dimethyltryptamine), ayahuasca and mescaline - have an ancient history across various civilizations.
S. Torres
doaj   +1 more source

Toxicological Analysis of Some Drugs of Abuse in Biological Samples [PDF]

open access: yes, 2015
Consumption of drugs of abuse is a scourge of modern world. Abuse, drug addiction and their consequences are one of the major current problems of European society because of the significant repercussions in individual, family, social and economic level ...
Baconi, Daniela Luiza   +5 more
core   +3 more sources

A Review of Aeruginascin and Potential Entourage Effect in Hallucinogenic Mushrooms

open access: yesEuropean Psychiatry, 2022
Introduction The 5-HT2A agonist classic psychedelic, psilocybin (O-phosphoryl-4-hydroxy-N,N-dimethyltryptamine) is a tryptophan, indole-based alkaloid present in up to 2% of certain hallucinogenic “magic” mushroom species; typically Psilocybe azurescens,
P. Chue   +4 more
doaj   +1 more source

The varieties of the psychedelic experience: A preliminary study of the association between the reported subjective effects and the binding affinity profiles of substituted phenethylamines and tryptamines [PDF]

open access: yes, 2018
Classic psychedelics are substances of paramount cultural and neuroscientific importance. A distinctive feature of psychedelic drugs is the wide range of potential subjective effects they can elicit, known to be deeply influenced by the internal state of
Erowid, Earth   +6 more
core   +2 more sources

Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies

open access: yesBrazilian Journal of Psychiatry, 2016
Objective: To conduct a systematic literature review of animal and human studies reporting anxiolytic or antidepressive effects of ayahuasca or some of its isolated alkaloids (dimethyltryptamine, harmine, tetrahydroharmine, and harmaline).
Rafael G. dos Santos   +3 more
doaj   +1 more source

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