Results 21 to 30 of about 2,551 (177)

Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report

open access: yesBrazilian Journal of Psychiatry, 2015
Objectives: Ayahuasca (AYA), a natural psychedelic brew prepared from Amazonian plants and rich in dimethyltryptamine (DMT) and harmine, causes effects of subjective well-being and may therefore have antidepressant actions.
Flávia de L. Osório   +9 more
doaj   +1 more source

Psychedelics: A new era of treatment?

open access: yesEuropean Psychiatry, 2021
Introduction Psychedelics - including LSD (lysergic acid diethylamide), psilocybin, DMT (N, N-dimethyltryptamine), ayahuasca and mescaline - have an ancient history across various civilizations.
S. Torres
doaj   +1 more source

A Review of Aeruginascin and Potential Entourage Effect in Hallucinogenic Mushrooms

open access: yesEuropean Psychiatry, 2022
Introduction The 5-HT2A agonist classic psychedelic, psilocybin (O-phosphoryl-4-hydroxy-N,N-dimethyltryptamine) is a tryptophan, indole-based alkaloid present in up to 2% of certain hallucinogenic “magic” mushroom species; typically Psilocybe azurescens,
P. Chue   +4 more
doaj   +1 more source

Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies

open access: yesBrazilian Journal of Psychiatry, 2016
Objective: To conduct a systematic literature review of animal and human studies reporting anxiolytic or antidepressive effects of ayahuasca or some of its isolated alkaloids (dimethyltryptamine, harmine, tetrahydroharmine, and harmaline).
Rafael G. dos Santos   +3 more
doaj   +1 more source

N,N‐dimethyltryptamine and Amazonian ayahuasca plant medicine [PDF]

open access: yesHuman Psychopharmacology: Clinical and Experimental, 2022
AbstractObjectiveReports have indicated possible uses of ayahuasca for the treatment of conditions including depression, addictions, post‐traumatic stress disorder, anxiety and specific psychoneuroendocrine immune system pathologies. The article assesses potential ayahuasca and N,N‐dimethyltryptamine (DMT) integration with contemporary healthcare.
Edward James   +3 more
openaire   +3 more sources

1H Nuclear Magnetic Resonance: A Future Approach to the Metabolic Profiling of Psychedelics in Human Biofluids?

open access: yesFrontiers in Psychiatry, 2021
While psychedelics may have therapeutic potential for treating mental health disorders such as depression, further research is needed to better understand their biological effects and mechanisms of action when considering the development of future novel ...
Sylvana Vilca-Melendez   +3 more
doaj   +1 more source

In silico study of dimethyltryptamine analogues against 5-HT1B receptor: Molecular docking, dynamic simulations and ADMET prediction [PDF]

open access: yesJournal of HerbMed Pharmacology, 2022
Introduction: The 5-HT1B receptor has a potential role in various psychiatric disorders such as depression, anxiety, and post-traumatic stress disorder.
Neyder Contreras   +2 more
doaj   +1 more source

Concise Synthesis of -Dimethyltryptamine and 5-Methoxy--dimethyltryptamine Starting with Bufotenine from Brazilian ssp

open access: yesNatural Product Communications, 2015
Bufotenine ( 1 , 5-hydroxy- N,N -dimethyltryptamine) was isolated from seeds of Anadenanthera spp., a tree widespread in the Brazilian cerrado, using an efficient acid-base shakeout protocol. The conversion of bufotenine into N,N -dimethyltryptamine ( 4 )
Leandro A. Moreira   +4 more
doaj   +1 more source

Targeting INMT and interrupting its methylation pathway for the treatment of castration resistant prostate cancer

open access: yesJournal of Experimental & Clinical Cancer Research, 2021
Background Castration-resistant prostate cancer (CRPC) is associated with a very poor prognosis, and the treatment of which remains a serious clinical challenge.
Shangwei Zhong   +7 more
doaj   +1 more source

Rumors of Psychedelics, Psychotropics and Related Derivatives in Vachellia and Senegalia in Contrast with Verified Records in Australian Acacia

open access: yesPlants, 2022
There are almost 1000 species of Acacia sensu stricto in Australia, while the 44 species and 4 subspecies in southern Africa were taxonomically revised in the year 2011 to Senegalia and Vachellia.
Nicholas J. Sadgrove
doaj   +1 more source

Home - About - Disclaimer - Privacy