Results 21 to 30 of about 2,930 (198)
Frontiers in Pharmacology, 2016 The state of consciousness induced by N,N-dimethyltryptamine (DMT) is one of the most extraordinary of any naturally-occurring psychedelic substance.
Andrew Robert Gallimore, Rick Strassman
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Extraction and Characterization of N,N‑Dimethyltryptamine from Mimosa tenuiflora: A Multivariate Approach [PDF]
ACS OmegaLucas Cordeiro de Oliveira +10 more
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Brazilian Journal of Psychiatry, 2015 Objectives: Ayahuasca (AYA), a natural psychedelic brew prepared from Amazonian plants and rich in dimethyltryptamine (DMT) and harmine, causes effects of subjective well-being and may therefore have antidepressant actions.
Flávia de L. Osório +9 more
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A Review of Aeruginascin and Potential Entourage Effect in Hallucinogenic Mushrooms
European Psychiatry, 2022 Introduction The 5-HT2A agonist classic psychedelic, psilocybin (O-phosphoryl-4-hydroxy-N,N-dimethyltryptamine) is a tryptophan, indole-based alkaloid present in up to 2% of certain hallucinogenic “magic” mushroom species; typically Psilocybe azurescens,
P. Chue +4 more
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Dimethyltryptamine: Endogenous Role and Therapeutic Potential [PDF]
Journal of Psychoactive Drugs, 2019 N, N-dimethyltryptamine (DMT) is an indole alkaloid produced by a number of plants and animals, including humans. Its psychoactive effects were first described in 1956 by Stephen Szára, but have been exploited for centuries by South American indigenous populations in the form of ayahuasca. In the present review, we assess the state of the art regarding
Alexandra Vsl, Rodrigues +2 more
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Psychedelics: A new era of treatment?
European Psychiatry, 2021 Introduction Psychedelics - including LSD (lysergic acid diethylamide), psilocybin, DMT (N, N-dimethyltryptamine), ayahuasca and mescaline - have an ancient history across various civilizations.
S. Torres
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The therapeutic potentials of ayahuasca: possible effects against various diseases of civilization
Frontiers in Pharmacology, 2016 Ayahuasca is an Amazonian psychoactive brew of two main components. Its active agents are β-carboline and tryptamine derivatives. As a sacrament, ayahuasca is still a central element of many healing ceremonies in the Amazon Basin and its ritual ...
Ede eFrecska +2 more
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Brazilian Journal of Psychiatry, 2016 Objective: To conduct a systematic literature review of animal and human studies reporting anxiolytic or antidepressive effects of ayahuasca or some of its isolated alkaloids (dimethyltryptamine, harmine, tetrahydroharmine, and harmaline).
Rafael G. dos Santos +3 more
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Frontiers in Psychiatry, 2021 While psychedelics may have therapeutic potential for treating mental health disorders such as depression, further research is needed to better understand their biological effects and mechanisms of action when considering the development of future novel ...
Sylvana Vilca-Melendez +3 more
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Pharmacokinetics of N,N-dimethyltryptamine in Humans
European Journal of Drug Metabolism and Pharmacokinetics, 2023 N,N-dimethyltryptamine (DMT) is a psychedelic compound under development for the treatment of major depressive disorder (MDD). This study evaluated the preclinical and clinical pharmacokinetics and metabolism of DMT in healthy subjects.The physiochemical properties of DMT were determined using a series of in vitro experiments and its metabolic profile ...
Meghan Good +11 more
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