“Algal-dromes”: a novel conceptual approach to illness in humans exposed to harmful algal bloom toxins [PDF]
Frontiers in ToxicologyAlthough adverse health effects from harmful algal bloom (HAB) toxins have been described since antiquity, the true worldwide incidence and disease burden has yet to be defined.
Brett Johnson +4 more
doaj +2 more sources
Toxins of Okadaic Acid-Group Increase Malignant Properties in Cells of Colon Cancer [PDF]
Toxins, 2020 Diarrhetic shellfish poisoning (DSP) is a syndrome caused by the intake of shellfish contaminated with a group of lipophilic and thermostable toxins, which consists of okadaic acid (OA), dinophysistoxin-1 (DTX-1) and dinophysistoxin-2 (DTX-2).
Danae Jiménez-Cárcamo +2 more
doaj +2 more sources
Toxicon, 2001 Okadaic acid (OA) homologues in toxic dinoflagellate Dinophysis fortii, scallops Patinopecten yessoensis and mussels Mytilus galloprovincialis collected at the same site in Mutsu Bay, Japan were determined by high-performance liquid chromatography fluorescence detection (HPLC-FLD) as their 9-anthryldiazomethane (ADAM) derivatives.
T Suzuki, T Mitsuya
core +3 more sources
Risk Assessment of Pectenotoxins in New Zealand Bivalve Molluscan Shellfish, 2009–2019
Toxins, 2020 Pectenotoxins (PTXs) are produced by Dinophysis spp., along with okadaic acid, dinophysistoxin 1, and dinophysistoxin 2. The okadaic acid group toxins cause diarrhetic shellfish poisoning (DSP), so are therefore regulated.
Michael J. Boundy +5 more
doaj +2 more sources
Dinophysis acuta in Scottish Coastal Waters and Its Influence on Diarrhetic Shellfish Toxin Profiles
Toxins, 2018 Diarrhetic shellfish toxins produced by the dinoflagellate genus Dinophysis are a major problem for the shellfish industry worldwide. Separate species of the genus have been associated with the production of different analogues of the okadaic acid group ...
Sarah C. Swan +7 more
doaj +2 more sources
Structure–Activity Relationship Studies Using Natural and Synthetic Okadaic Acid/Dinophysistoxin Toxins [PDF]
Marine Drugs, 2016 Okadaic acid (OA) and the closely related dinophysistoxins (DTXs) are algal toxins that accumulate in shellfish and are known serine/threonine protein phosphatase (ser/thr PP) inhibitors.
Michael J. Twiner +5 more
doaj +3 more sources
Quantitation of diarrhetic shellfish poisoning toxins in Chilean Mussel using pyrenyldiazomethane as fluorescent labeling reagent [PDF]
Biological Research, 2003 Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disease caused by lipid soluble polyether toxins produced by dinoflagellates and accumulated in shellfish.
CARLOS GARCÍA +3 more
doaj +2 more sources
First report of diarrheic shellfish toxins in mollusks from Buenos Aires province (Argentina) associated with dinophysis spp.: evidence of okadaic acid, dinophysistoxin-1 and their acylderivatives [PDF]
Boletín de la Sociedad Argentina de Botánica, 2012 In January 2010, the toxin-producing dinoflagellates Dinophysis acuminata and D. caudata (10³ cells·l-1) were detected in Mar Azul during routine plankton monitoring in Buenos Aires Province coastal waters, Argentina.
Eugenia A Sar +6 more
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Occurrence and risk assessment of okadaic acid, dinophysistoxin-1, dinophysistoxin-2, and dinophysistoxin-3 in seafood from South Korea. [PDF]
Environ Sci Pollut Res Int, 2023 AbstractThe okadaic acid (OA)-group toxins, including OA, dinophysistoxin-1 (DTX1), dinophysistoxin-2 (DTX2), and dinophysistoxin-3 (DTX3), cause diarrheic shellfish poisoning in humans. To manage OA-group toxins more strictly, Korean regulations were recently revised to consider OA, DTX1, DTX2, and DTX3 combined.
Park JB +4 more
europepmc +3 more sources
Rapid Communications in Mass Spectrometry, 2012 RATIONALE Most of the liquid chromatography/mass spectrometry (LC/MS) methods that have been developed for the analysis of Diarrhetic Shellfish Poisoning (DSP) toxins in shellfish and algae samples have been unable to differentiate the isomers okadaic ...
O'Halloran, John +5 more
core +6 more sources