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Bioactive Compounds and Antioxidant Capacity of Wild Edible Asparagus in the Iğdır Plain. [PDF]
Özden E +4 more
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AI-Driven Multiscale Study on the Mechanism of Polygonati Rhizoma in Regulating Immune Function in STAD. [PDF]
Yang P +7 more
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Journal of Pharmaceutical Sciences, 1968
The decomposition of 25α-Δ 5 -spirosten-3β-ol (diosgenin) has been studied by various physical techniques in the solid state, in contact with both 2 N hydrochloric acid and 2 N sodium carbonate solution, and in solution in both chloroform and benzene.
G, Blunden, C T, Rhodes
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The decomposition of 25α-Δ 5 -spirosten-3β-ol (diosgenin) has been studied by various physical techniques in the solid state, in contact with both 2 N hydrochloric acid and 2 N sodium carbonate solution, and in solution in both chloroform and benzene.
G, Blunden, C T, Rhodes
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Effect of diosgenin on cholesterol metabolism
Journal of Atherosclerosis Research, 1962Summary In chickens fed a stock diet with 2 % cholesterol, the addition of 0.2–2.0 % diosgenin ( Δ 5 -22 ɛ -spirosten-3 β -ol) prevented the resulting hypercholesterolemia. Animals were followed up from 22 to 100 days and at the end of the experimental period, serum cholesterol values averaged about 110–180 mg% in control animals, 700–850 mg% in the ...
J, LAGUNA +3 more
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European Journal of Pharmacology, 2020
(25R)-spirost-5-en-3β-ol, also known as diosgenin (DSG), exerts antiproliferative activity on diverse cell lines, induces apoptosis, and acts as a chemopreventative agent. However, the relationship between DSG glycosides and apoptotic, necrotic, and antiproliferative activity remains unclear.
José Misael Vicente, Hernández-Vázquez +8 more
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(25R)-spirost-5-en-3β-ol, also known as diosgenin (DSG), exerts antiproliferative activity on diverse cell lines, induces apoptosis, and acts as a chemopreventative agent. However, the relationship between DSG glycosides and apoptotic, necrotic, and antiproliferative activity remains unclear.
José Misael Vicente, Hernández-Vázquez +8 more
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Microbial modification of diosgenin and hecogenin
Journal of the Chemical Society, Perkin Transactions 1, 1973On incubation with an unidentified bacterium diosgenin [(25R)-spirost-5-en-3β-ol](1) was converted into (25R)-9-oxode-AB-spirostane-8α-propionic acid (3). Incubation with Nocardia globerula produced the same oxo-acid (3) and also a small amount of its 1 7α-hydroxy-derivative.
R, Howe +3 more
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Meiosis activating sterols derived from diosgenin
Bioorganic & Medicinal Chemistry Letters, 2002Continuing research based on the meiosis activation properties of the endogenous sterol FF-MAS is reported. The synthesis and SAR of 16- and 26-substituted sterols are described, utilising diosgenin as starting material. Selected sterols were tested for their ability to induce oocyte maturation in hypoxanthine arrested mouse oocytes in vitro.
Anthony, Murray +3 more
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