Results 131 to 140 of about 4,332 (163)

Biosynthesis of diosgenin in Dioscorea tubers

Archives of Biochemistry and Biophysics, 1961
Abstract The incorporation of radioacetate into diosgenin by homogenates of Dioscorea floribunda has been demonstrated by rigorous purification of the isolated sapogenin. Mevalonic acid is not incorporated into diosgenin to any significant extent under these conditions.
E, HEFTMANN, R D, BENNETT, J, BONNER
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Diosgenin saponins from Dioscorea floribunda

Phytochemistry, 1975
Abstract Five spirostanol glycosides and two furostanol glycosides were isolated from Dioscorea floribunda . In addition to the IR spectra of the free glycosides and the MS of the peracetates and permethyl ethers, the most effective method for structural determination proved to be the NMR spectra of the free saponins in pyridine- d 5 .
Georg-Alexander Hoyer, Wolfgang Sucrow, Dieter Winkler   +2 more
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Cardiovascular Effect of Diosgenin in Ovariectomized Rats

Journal of Medicinal Food, 2019
Diosgenin is a phytoestrogen and a constituent of Dioscorea. It has several biological effects, and some of them are anti-inflammatory, antidiabetic, antitumor, and vasodilatory. The present study investigated both the vasorelaxing and antioxidant mechanisms of diosgenin in isolated rat aortic rings.
Ilmara Cecilia Pinheiro de Silva, Morais, Iris Jordânia Luz, Moura, Carla Kelly Barroso, Sabino, Lucas Antonio Duarte, Nicolau, Fabiana de Moura, Souza, José Couras da, Silva-Filho, Rita de Cássia Meneses, Oliveira, Jand Venes Rolim, Medeiros, Sidney Gonçalo de, Lima, Aldeidia Pereira de, Oliveira   +9 more
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Diosgenin aus Yams als Hormonvorstufe

Chemie in unserer Zeit, 2015
AbstractDas Sapogenin Diosgenin ist das Aglykon des Saponins Dioscin. Es kommt in Pflanzen wie Yams vor, aus denen es seit den 1940er Jahren in industriellem Maßstab isoliert wird. Pflanzliches Diosgenin ist Ausgangsstoff für die Synthese menschlicher, und damit tierischer Hormone und “der Pille”, die als hormonelles Verhütungsmittel eine Revolution in
Anna Rudo, Hans‐Ullrich Siehl, Klaus‐Peter Zeller, Stefan Berger, Dieter Sicker   +4 more
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Novel effects of diosgenin on skin aging

Steroids, 2009
Extracts of Dioscorea coomposita or Dioscorea villosa are consumed as supplemental health foods at the time of climacteric. The extracts contain large amounts of the plant steroid, diosgenin. Here, we studied the safety and efficacy of diosgenin against skin aging at the time of climacteric. In vitro, diosgenin enhanced DNA synthesis in a human 3D skin
Yayoi, Tada, Naoko, Kanda, Akinori, Haratake, Megumi, Tobiishi, Hideyo, Uchiwa, Shinichi, Watanabe   +5 more
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Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line

Molecular Biology Reports, 2014
Trigonella foenum-graecum generally known as fenugreek, has been normally cultivated in Asia and Africa for the edible and medicinal values of its seeds. Fenugreek leaves and seeds have been used widely for therapeutic purposes. Fenugreek seed is recognized to show anti-diabetic and anti-nociceptive properties and other things such as ...
Mohammad, Rahmati-Yamchi, Somayyeh, Ghareghomi, Gholamreza, Haddadchi, Morteza, Milani, Mohammad, Aghazadeh, Hasan, Daroushnejad   +5 more
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Diosgenin: Therapeutic Action, Pharmacology and Applications

Science & Technology Journal, 2017
Diosgenin [25R-spriost-5-en-3þ-ol], is an important steroidal metabolite found in various plant species. The discovery of diosgenin has made it one of the most researched and studied herbal product. Moreover, there is excellent opportunity to address whether diosgenin plays a role in chemoprevention versus therapy, or both.
Sanasam Sanjeev, Maibam Sunita Devi, Khushboo Maurya, Vikas Kumar Roy, Guruswami Gurusubramanian   +4 more
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Solubility of diosgenin in different solvents

The Journal of Chemical Thermodynamics, 2012
Abstract The solubility of diosgenin in methanol, ethanol (95%), isopropanol, acetone, acetic ether, and propyl acetate were measured at temperatures from (295.15 to 330.15) K using the synthetic method by a laser monitoring observation technique at atmospheric pressure.
Fei-xiong Chen, Ming-rui Zhao, Bao-zeng Ren, Cai-rong Zhou, Fei-fei Peng   +4 more
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Sterols. C. Diosgenin¹

Journal of the American Chemical Society, 1940
Reactions of diosgenin a sterol isolated from an extract of Dioscorea tokoro are discussed. Diosgenin is known to possess a 56 double bond and 1 nuclear hydroxyl group in the 3-position with the beta configuration appearing as in cholesterol. The compound was subjected to reactions applied to sarsasapogenin and other steroidal sapogenins for the ...
Russell E. Marker, Takeo Tsukamoto, D. L. Turner   +2 more
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Chemodifferentiation of diosgenin in Dioscorea composita

Phytochemistry, 1984
Abstract Diosgenin was isolated from different parts of a three-year-old plant of Dioscorea composite . The amounts (% on a dry wt basis) present were: tubers, 3.6; vine internodes and nodes with their leaves from first 20 nodes from the tubers, 1.6; similarly from intermediate 20 nodes, 0.039 and from upper 20 nodes, 0.03.
S.K. Datta, Karabi Datta
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