Results 91 to 100 of about 25,787 (305)

Strigolactone biosynthesis is evolutionarily conserved, regulated by phosphate starvation and contributes to resistance against phytopathogenic fungi in a moss, Physcomitrella patens [PDF]

, 2017
In seed plants, strigolactones (SLs) regulate architecture and induce mycorrhizal symbiosis in response to environmental cues. SLs are formed by combined activity of the carotenoid cleavage dioxygenases (CCDs) 7 and 8 from 9-cis-β-carotene, leading to ...
Alder, Adrian, Balakrishna, Aparna, Decker, Eva L., Ferguson, Jenny, Hunn, Stefan, Kerres, Klaus L., Lehtonen, Mikko T., Nordzieke, Steffen, Safavi-Rizi, Vajiheh, Scheler, Bjoern, Wiedemann, Gertrud, Ávalos Cordero, Francisco Javier   +11 more
core   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Oncometabolites: tailoring our genes [PDF]

, 2015
Increased glucose metabolism in cancer cells is a phenomenon that has been known for over 90 years, allowing maximal cell growth through faster ATP production and redistribution of carbons towards nucleotide, protein and fatty acid synthesis.
Avril N, Buck AC, Gimm O, Higashi K
core   +1 more source

2-Oxoglutarate-dependent dioxygenases in the biosynthesis of simple coumarins

Frontiers in Plant Science, 2014
Coumarins are natural plant products that have been the subject of extensive phytochemical and pharmacological research studies in the past few decades.
Bun-Ichi eShimizu
doaj   +1 more source

Discovery of a new subgroup of sulfur dioxygenases and characterization of sulfur dioxygenases in the sulfur metabolic network of Acidithiobacillus caldus.

PLoS ONE, 2017
Acidithiobacillus caldus is a chemolithoautotrophic sulfur-oxidizing bacterium that is widely used for bioleaching processes. Acidithiobacillus spp. are suggested to contain sulfur dioxygenases (SDOs) that facilitate sulfur oxidation.
Wei Wu, Xin Pang, Jianqiang Lin, Xiangmei Liu, Rui Wang, Jianqun Lin, Linxu Chen   +6 more
doaj   +1 more source

TT2013 meeting report: the transgenic technology meeting visits Asia for the first time [PDF]

, 2013
The 11th Transgenic Technology meeting was held in Guangzhou, China on 25th–27th February 2013. Over 300 scientists and students from round the world gathered to hear the latest developments in the technologies underpinning the creation of transgenic and
Strathdee, D., Whitelaw, C.B.A.
core   +3 more sources

Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production

Animal Research and One Health, EarlyView.
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu, Samantha Howe, Yang Tian, Alisun N. Watson, Jason E. Farrar, Christopher E. Randolph, Jaime Andrés Ángel Isaza, Álvaro José Uribe, Yan Huang, Michael Looper, Jiangchao Zhao, Tsungcheng Tsai   +11 more
wiley   +1 more source

Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study [PDF]

, 2012
How cells ensure correct metallation of a given protein and whether a degree of promiscuity in metal binding has evolved are largely unanswered questions.
Abbouni, Aguirre, Akana, Altuvia, Andersson, Anjem, Anjem, Archibald, Arciero, Arciero, Aslund, Atkin, Atta, Auling, Balasubramanian, Barnese, Barnese, Bellini, Beyer, Jr, Boal, Boal, Boal, Boldt, Bollinger, Jr, Bollinger, Jr, Bollinger, Jr, Borgstahl, Böck, Changela, Chiancone, Choi, Cotruvo, Jr, Cotruvo, Jr, Cotruvo, Jr, Cotruvo, Jr, Cox, Crona, Cvetkovic, Daly, Daly, Das, Dassama, Dunning Hotopp, Ehrenberg, Emerson, Eriksson, Ezra, Fee, Fielding, Fieschi, Gibello, Golynskiy, Gon, Griepenburg, Guedon, Gunderson, Han, Hatta, Helmann, Hitomi, Hristova, Hu, Huque, Högbom, Högbom, Högbom, Högbom, Högbom, Imlay, Jacobsen, Jang, Jiang, Jiang, Jiang, JoAnne Stubbe, Johnson, Jordan, Jordan, Jordan, Joseph A. Cotruvo, Jr, Kauppi, Kehl-Fie, Kehres, Kehres, Keyer, Kobayashi, Kovaleva, Kovaleva, Krebs, Lah, Larsson, Layer, Leitgeb, Licht, Lill, Lipscomb, Lundin, Maier, Maliekal, Maret, Martin, Massé, Mbughuni, Mbughuni, McHugh, McNaughton, Meier, Miller, Miller, Mills, Miyazawa, Mizuno, Monje-Casas, Mühlenhoff, Nandal, Naranuntarat, Nesbit, Nordlund, Nordlund, O'Halloran, Oka, Okamoto, Outten, Panosa, Papp-Wallace, Park, Passalacqua, Pericone, Peters, Philpott, Pierce, Pierce, Plönzig, Privalle, Que, Jr, Rae, Raimunda, Rajagopalan, Reece, Robinson, Roca, Roos, Rosenzweig, Sawyer, Sazinsky, Schimpff-Weiland, Schwartz, Scott, Sen, Shanmugam, Shi, Shi, Sjöberg, Sjöberg, Sobota, Solomon, Stemmler, Stolle, Stubbe, Stubbe, Stubbe, Tomter, Tong, Torrents, Tottey, Tu, Uhlin, Umback, Uppsten, Vaillancourt, Vance, Varghese, Vassinova, Vetting, Voegtli, Voevodskaya, Voevodskaya, Voevodskaya, Wan, Whittaker, Willing, Wu, Xu, Yun, Yun, Zaharik, Zhang, Zheng, Zhou   +188 more
core   +1 more source

Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale, Monica Chu, Sally Wang, Divya Muthusamy, Eric Wold, Yi Liu, G. F. Payne, Tanya Tschirhart, W. E. Bentley   +8 more
wiley   +1 more source

Substrate specificity of a branch of aromatic dioxygenases determined by three distinct motifs

Nature Communications
The inversion of substrate size specificity is an evolutionary roadblock for proteins. The Duf4243 dioxygenases GedK and BTG13 are known to catalyze the aromatic cleavage of bulky tricyclic hydroquinone.
Chengsen Cui, Lu-Jia Yang, Zi-Wei Liu, Xian Shu, Wei-Wei Zhang, Yuan Gao, Yu-Xuan Wang, Te Wang, Chun-Chi Chen, Rey-Ting Guo, Shu-Shan Gao   +10 more
doaj   +1 more source