Results 181 to 190 of about 14,175 (245)

Impact of Docking Strand Design on Spatial Resolution in DNA‐Points Accumulation for Imaging in Nanoscale Topography

open access: yesChemPhysChem, Volume 27, Issue 5, 13 March 2026.
The design of DNA‐PAINT docking strands critically influences spatial resolution and signal stability. By comparing single (1 × R1) and repetitive (5 × R1) docking architectures on PCNA, we reveal how binding kinetics and localization precision determine the accuracy of sub‐10 nm imaging in protein nanostructures. DNA points accumulation for imaging in
Dominic A. Helmerich   +5 more
wiley   +1 more source

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

open access: yesChemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret   +9 more
wiley   +1 more source

CRK2 modulates flowering in Arabidopsis together with GLYCINE‐RICH RNA‐BINDING PROTEIN 7

open access: yes
New Phytologist, Volume 250, Issue 2, Page 702-707, April 2026.
Francisco J. Colina   +3 more
wiley   +1 more source

Metabolic mechanism of lignin-derived aromatics in white-rot fungi. [PDF]

open access: yesAppl Microbiol Biotechnol
Kato H, Miura D, Kato M, Shimizu M.
europepmc   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard   +8 more
wiley   +1 more source

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