Results 181 to 190 of about 34,889 (336)

Identification and localization of 3-phenylcatechol dioxygenase and 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase genes of Pseudomonas putida and expression in Escherichia coli [PDF]

, 1990
Ashraf A. Khan, Sandeep Walia
openalex   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

A new role for PHYHD1 and related dioxygenases: demethylation of 2'-O-methylated nucleosides. [PDF]

Nucleic Acids Res
Stonkus J, Rutkienė R, Meškienė R, Jasiūnienė M, Aučynaitė A, Kalinienė L, Lazutka J, Balčiūnas D, Vilkaitis G, Meškys R.   +9 more
europepmc   +1 more source

Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2,3-dioxygenase (IDO) inhibitors

, 2013
Minoru Tanaka, Xin Li, Hidemasa Hikawa, Takafumi Suzuki, Katsuhiko Tsutsumi, Masashi Sato, Osamu Takikawa, Hideharu Suzuki, Yuusaku Yokoyama   +8 more
openalex   +1 more source

Monovalent mannose‐glycoconjugates of sulforaphane reprogram human dendritic cells via NFATc1 to induce immune tolerance under inflammatory conditions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez, Camila Leiva‐Castro, Ana M. Múnera‐Rodríguez, Macarena Martínez‐Bailén, Ana T. Carmona, Soledad López‐Enríquez, Francisca Palomares   +6 more
wiley   +1 more source

Draft genome sequence of the meloxicam-degrading <i>Gordonia alkanivorans</i> IEGM 1277 strain. [PDF]

Microbiol Resour Announc
Tyan SM, Ivshina IB.
europepmc   +1 more source

Negligible amount of copper in hepatic L-tryptophan 2,3-dioxygenase.

, 1976
Ryu Makino, Yuzuru Ishimura
openalex   +1 more source

Molecular Basis for the Stabilization and Inhibition of 2,3-Dihydroxybiphenyl 1,2-Dioxygenase by t-Butanol [PDF]

, 1998
Frédéric H. Vaillancourt, Seungil Han, Pascal D. Fortin, Jeffrey T. Bolin, Lindsay D. Eltis   +4 more
openalex   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Draft genome sequence of <i>Rhodococcus pyridinivorans</i> IEGM 66, a betulin biotransformer. [PDF]

Microbiol Resour Announc
Plotnitskaya NA, Krivoruchko AV, Ivshina IB.   +2 more
europepmc   +1 more source