Results 11 to 20 of about 21,027 (334)

Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase. [PDF]

open access: yesPLoS ONE, 2008
Deoxynucleoside triphosphates (dNTPs) are the normal substrates for DNA synthesis catalyzed by polymerases such as HIV-1 reverse transcriptase (RT). However, substantial amounts of deoxynucleoside diphosphates (dNDPs) are also present in the cell. Use of
Scott J Garforth   +2 more
doaj   +6 more sources

Oritavancin Diphosphate [PDF]

open access: yesHospital Pharmacy, 2014
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing
Dennis J, Cada, Danial E, Baker
openaire   +2 more sources

URIDINE DIPHOSPHATE ACETYLGLUCOSAMINE

open access: yesJournal of Biological Chemistry, 1953
Blanco y ...
Cabib, Enrico   +2 more
openaire   +6 more sources

Nucleoside Diphosphate Prodrugs [PDF]

open access: yesNucleic Acids Symposium Series, 2008
Nucleoside analogs are widely applied in antiviral and antitumor therapy. A severe limitation of these compounds arises from the need of biotransformation to the eventually active nucleoside triphosphates by stepwise addition of phosphate by kinases. This problem can be circumvented by employing reversibly masked nucleotides (prodrugs).
Meier, Chris   +2 more
openaire   +3 more sources

Cloning and characterisation of chlorophyll synthase from Avena sativa [PDF]

open access: yes, 2001
The chlorophyll synthase gene from oat (Avena sativa) was cloned and expressed in Escherichia coli. The deduced amino acid sequence consists of 378 amino acids including a presequence, of 46 amino acids.
Kögel, Julia   +4 more
core   +1 more source

Making Molecules with Clay: Layered Double Hydroxides, Pentopyranose Nucleic Acids and the Origin of Life

open access: yesLife, 2019
A mixture of sugar diphosphates is produced in reactions between small aldehyde phosphates catalysed by layered double hydroxide (LDH) clays under plausibly prebiotic conditions.
Harold S. Bernhardt
doaj   +1 more source

The Heptaprenyl Diphosphate Synthase (Coq1) Is the Target of a Lipophilic Bisphosphonate That Protects Mice against Toxoplasma gondii Infection

open access: yesmBio, 2022
Prenyldiphosphate synthases catalyze the reaction of allylic diphosphates with one or more isopentenyl diphosphate molecules to form compounds such as farnesyl diphosphate, used in, e.g., sterol biosynthesis and protein prenylation, as well as longer ...
Melissa A. Sleda   +9 more
doaj   +1 more source

Transcriptional profile of genes involved in the production of terpenes and glyceollins in response to biotic stresses in soybean [PDF]

open access: yesGenetics and Molecular Biology, 2020
Terpenes produced by plants comprise a diverse range of secondary metabolites, including volatile organic compounds (VOCs). Terpene VOC production may be altered after damage or by biological stimuli such as bacterial, fungal and insects, and subsequent ...
Talitta Regina Parmezan   +9 more
doaj   +1 more source

The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 angstrom resolution [PDF]

open access: yes, 2008
Maturation of tRNA precursors into functional tRNA molecules requires trimming of the primary transcript at both the 5' and 3' ends. Cleavage of nucleotides from the 3' stem of tRNA precursors, releasing nucleotide diphosphates, is accomplished in ...
Blagova, Elena V.   +5 more
core   +2 more sources

In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet [PDF]

open access: yes, 2007
International ...
Croubels, Siska   +6 more
core   +3 more sources

Home - About - Disclaimer - Privacy