Results 31 to 40 of about 20,669 (341)

Harnessing enzyme plasticity for the synthesis of oxygenated sesquiterpenoids

open access: yesBeilstein Journal of Organic Chemistry, 2019
8-Methoxy-γ-humulene, (E)-8-methoxy-β-farnesene, 12-methoxy-β-sesquiphellandrene and 12-methoxyzingiberene can be synthesised in amorphadiene synthase-catalysed reactions from 8- and 12-methoxyfarnesyl diphosphates due to the highly plastic yet tightly ...
Melodi Demiray   +2 more
doaj   +1 more source

Characterisation of a Recombinant Patchoulol Synthase Variant for Biocatalytic Production of Terpenes [PDF]

open access: yes, 2015
The patchoulol synthase (PTS) is a multi-product sesquiterpene synthases which is the central enzyme for biosynthesis of patchouli essential oil in the patchouli plant.
Alemdar, Semra   +6 more
core   +1 more source

Interlinked GTPase cascades provide a motif for both robust switches and oscillators [PDF]

open access: yesJ. R. Soc. Interface 16, 20190198 (2019), 2019
GTPases regulate a wide range of cellular processes, such as intracellular vesicular transport, signal transduction, and protein translation. These hydrolase enzymes operate as biochemical switches by toggling between an active guanosine triphosphate (GTP)-bound state and an inactive guanosine diphosphate (GDP)-bound state.
arxiv   +1 more source

Enzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replication. [PDF]

open access: yesPLoS Computational Biology, 2011
Using a computational model, we simulated mitochondrial deoxynucleotide metabolism and mitochondrial DNA replication. Our results indicate that the output from the mitochondrial salvage enzymes alone is inadequate to support a mitochondrial DNA ...
Vishal V Gandhi, David C Samuels
doaj   +1 more source

Ribonucleotide reductase subunit M2 predicts survival in subgroups of patients with non-small cell lung carcinoma: effects of gender and smoking status.

open access: yesPLoS ONE, 2015
BackgroundRibonucleotide reductase catalyzes the conversion of ribonucleotide diphosphates to deoxyribonucleotide diphosphates. The functional enzyme consists of two subunits - one large (RRM1) and one small (RRM2 or RRM2b) subunit.
Vei Mah   +10 more
doaj   +1 more source

Sites of synthesis and transport of photosynthetic products within the leaf cell [PDF]

open access: yes, 1964
1.1. After illumination of leaves in the presence of 14CO2 for various times and subsequent freeze drying, chloroplasts were isolated using a nonaqueous procedure.
Heber, U., Willenbrink, J.
core   +1 more source

In vitro degradation of guanosine 5'-diphosphate, 3'-diphosphate. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1977
The degradation of guanosine 5'-diphosphate,3'-diphosphate (ppGpp) by the "crude" ribosomal fraction of Escherichia coli CP78 (rel+, spoT+) was demonstrated and characterized. When the 3'-pyrophosphoryl group of ppGpp was hydrolyzed, the primary degradation product was 5'-GDP. Phosphorylation of ppGpp to guanosine 5'-triphosphate,3'-diphosphate (pppGpp)
openaire   +3 more sources

The Product Specificities of Maize Terpene Synthases TPS4 and TPS10 Are Determined Both by Active Site Amino Acids and Residues Adjacent to the Active Site

open access: yesPlants, 2020
Terpene synthases make up a large family of enzymes that convert prenyl diphosphates into an enormous variety of terpene skeletons. Due to their electrophilic reaction mechanism—which involves the formation of carbocations followed by hydride shifts and ...
Tobias G. Köllner   +2 more
doaj   +1 more source

Emulsifiers in ultra-processed foods in the UK food supply

open access: yesPublic Health Nutrition, 2023
Objective: Ultra-processed foods (UPF), including those containing food additive emulsifiers, have received research attention due to evidence implicating them in the pathogenesis of certain diseases.
Alicia Sandall   +3 more
doaj   +1 more source

Interactions between the transmembrane domains of CD39: identification of interacting residues by yeast selection.

open access: yesScienceOpen Research, 2014
Rat CD39, a membrane-bound ectonucleoside triphosphate diphosphohydrolase that hydrolyzes extracellular nucleoside tri- and diphosphates, is anchored to the membrane by two transmembrane domains at the two ends of the molecule.
Guido Guidotti, Sari Paavilainen
doaj   +1 more source

Home - About - Disclaimer - Privacy