Results 111 to 120 of about 314,031 (226)
Characterization of a transgenic mouse model of chronic conditional platelet depletion
Research and Practice in Thrombosis and Haemostasis, 2019 Background Platelets are widely recognized for their role in maintaining hemostasis. Recently, platelets have become appreciated for their varying roles in immunity, neuroprotection, and other physiological processes.
Leah M. Wuescher +2 more
doaj +1 more source
TOXIN-ANTITOXIN IMMUNIZATION AGAINST DIPHTHERIA
, 1922 The development of antitoxin in the bodies of animals injected with diphtheria toxin is one of the best established of facts. Since von Behring and Roux announced the results of their investigations, large numbers of horses have been injected with toxin ...
W. H. Park
semanticscholar +1 more source
Clinical Cancer Research, 2012 Purpose: The novel fusion protein, DAB389EGF, is composed of both the catalytic and the translocation domains of diphtheria toxin that are fused to the human EGF, providing a targeting and a toxicity component.
Xiaoping Yang +11 more
semanticscholar +1 more source
BMC Microbiology, 2012 BackgroundCorynebacterium ulcerans can cause a diphtheria-like illness, especially when the bacterium is lysogenized with a tox gene-carrying bacteriophage that produces diphtheria toxin.
T. Sekizuka +7 more
semanticscholar +1 more source
Data in Brief, 2022 Corynebacterium diphtheriae (C. diphtheriae) is the causative agent of diphtheria. The main virulence factor of C. diphtheriae is diphtheria toxin, which is encoded by the tox gene and regulated by the dtxR gene.
Vivi Setiawaty +11 more
doaj
Severe diphtheria with neurologic and myocardial involvement in a Swedish patient: a case report
BMC Infectious Diseases, 2018 Background Diphtheria is caused by Corynebacterium diphtheriae. Although waning in incidence diphtheria can cause severe disease as in this rare Swedish case with several complications. Case presentation A 55-year old male presented to the emergency room
Sten Skogmar, Johan Tham
doaj +1 more source
Clinical and Vaccine Immunology, 2011 A nonspecific binding of antibodies to diphtheria toxin, especially in adult serum samples, was observed in our diphtheria-tetanus-pertussis multiplex immunoassay (DTaP4 MIA). This can be significantly reduced by the use of diphtheria toxoid, achieving a
P. V. van Gageldonk +3 more
semanticscholar +1 more source
Development of a diphtheria toxin based antiporcine CD3 recombinant immunotoxin.
Bioconjugate chemistry, 2011 Anti-CD3 immunotoxins, which induce profound but transient T-cell depletion in vivo by inhibiting eukaryotic protein synthesis in CD3+ cells, are effective reagents in large animal models of transplantation tolerance and autoimmune disease therapy.
Zhirui Wang +8 more
semanticscholar +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019 Background and Objectives: Cancer is one of the most deadly diseases in the present age and its conventional therapies have had low success. Toxin therapy of cancer is a new therapeutic approach, which has attracted the attention of pharmaceutical ...
Mohaddeseh Parvand +2 more
doaj
Is Diphtheria Booster Vaccination Still Necessary in Turkey?
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2018 Introduction: Diphtheria is a serious disease that can be prevented by vaccination. The aim of the study was to determine immunity against diphtheria and the necessity of booster doses in the adult population.Materials and Methods: Serum antibody levels ...
Sule Eren CAKAR +5 more
doaj +1 more source