Results 21 to 30 of about 89,499 (267)
THE PRODUCTION OF DIPHTHERIA TOXIN [PDF]
Journal of Experimental Medicine, 1896 Toxin of sufficient strength to kill a 400-gramme guinea-pig in three days and a half in a dose of 0·cubic centimetre developed in suitable bouillon, contained in ordinary Erlenmeyer flasks, within a period of twenty-four hours. In such boullon the toxin reached its greatest strength in from four to seven days (0·005 cubic centimetre killing a 500 ...
W H, Park, A W, Williams
openaire +2 more sources
Investigation of the Effect of PEG Detoxification on Diphtheria Vaccine [PDF]
Archives of Razi Institute, 2022 Immunization has been considered a successful global health program that saves many persons’ lives each year. The vaccines reduce the risk of getting the disease by building immunity in the body. Therefore, the constant availability of essential vaccines
T Hesari +6 more
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SINGLE CHAIN VARIABLE FRAGMENTS OF ANTIBODIES AGAINST DIPHTHERIA TOXIN B-SUBUNIT ISOLATED FROM PHAGE DISPLAY HUMAN ANTIBODY LIBRARY [PDF]
Biotechnologia Acta, 2014 Diphtheria toxin is an exoantigen of Corynebacterium diphtheriae that inhibits protein synthesis and kills sensitive cells. The aim of this study was to obtain human recombinant single-chain variable fragment (scFv) antibodies against receptor-binding B ...
Oliinyk O. S. +3 more
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METHODS OF CONTROL DIPHTHERIA VACCINE SAFETY [PDF]
Annals of Mechnikov's Institute, 2016 Vaccination success depends not only on the timely coverage of threatened contingents, but also on the quality of vaccines. Every day, the requirements for security guarantees vaccines and their use guarantees of security increases.
Isayenko Ye. Yu +5 more
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The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement [PDF]
, 1980 Lysosomotropic amines, such as ammonium chloride, are known to protect cells from the cytotoxic effects of diphtheria toxin. These drugs are believed to inhibit the transport of the toxin from a receptor at the cell exterior into the cytoplasm where a ...
Draper, Rockford K., Simon, Melvin I.
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Diphtheria: A case series from West Maharashtra, India
Journal of Medical Sciences and Health, 2022 Diphtheria is an acute infectious toxin mediated disease caused by Corynebacterium diphtheriae. Effective vaccination has decreased the incidence of disease globally. However, despite of a full-fledged Universal Immunization Programme, the cases
Snehal Patil +3 more
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Diphtheritic myocarditis: A case series and review of literature
Journal of Family Medicine and Primary Care, 2020 Myocarditis in patients with diphtheria is a toxin-mediated complication that sets in after one week of onset of respiratory illness. Early administration of antidiphtheritic serum in patients with clinical diphtheria before the onset of myocarditis is ...
Sonali Singh, Nitin Gupta, Pallavi Saple
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Genetic characterization of diphtheria tox B to evaluate vaccine efficacy in Indonesia
Iranian Journal of Microbiology, 2022 Background and Objectives: Blocking the attachment of diphtheria toxins to host cells through the intact receptor binding site (tox B) was the initial mechanism of action of the diphtheria vaccine.
Yeva Rosana +2 more
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Retrograde transport pathways utilised by viruses and protein toxins [PDF]
, 2006 A model has been presented for retrograde transport of certain toxins and viruses from the cell surface to the ER that suggests an obligatory interaction with a glycolipid receptor at the cell surface. Here we review studies on the ER trafficking cholera
Easton, A. J. (Andrew J.) +4 more
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Macrophage depletion disrupts immune balance and energy homeostasis. [PDF]
, 2014 Increased macrophage infiltration in tissues including white adipose tissue and skeletal muscle has been recognized as a pro-inflammatory factor that impairs insulin sensitivity in obesity.
Feng, Gen-Sheng +4 more
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